Abstract: A system for assisting patients in sorting and dispensing medication supplies comprises a storage tray having a number of storage compartments, and a communication system to identify a medication to be provided from a pill bottle and, based upon the identification and a known regime, automatically identify which compartments of the storage tray are to be filled with the identified medication from the pill bottle and perform the filling of the storage tray. In doing so, a patient can simply open and present any number of pill bottles to the system, and then allow the system to arrange the medication in the storage tray according to the known regimen. The regimen and regimen updates are communicated to the system by means of a wired or wireless transmission to the system from a remote location (e.g. pharmacy or doctor's office), by direct user input, or by reading such information from a barcode or similar information carrier affixed to the pill bottles.

Abstract: A system for assisting patients in sorting and dispensing medication supplies comprises a storage tray having a number of storage compartments, and a communication system to identify a medication to be provided from a pill bottle and, based upon the identification and a known regime, automatically identify which compartments of the storage tray are to be filled with the identified medication from the pill bottle and perform the filling of the storage tray. In doing so, a patient can simply open and present any number of pill bottles to the system, and then allow the system to arrange the medication in the storage tray according to the known regimen. The regimen and regimen updates are communicated to the system by means of a wired or wireless transmission to the system from a remote location (e.g. pharmacy or doctor's office), by direct user input, or by reading such information from a barcode or similar information carrier affixed to the pill bottles.

Abstract: A system comprising a medication tray (10) and a docking station (20) for facilitating effective self-management of medication treatment by patients is provided. The medication tray (10) accepts medication filled containers (30) and mates with the docking station (20). The medication tray (10) receives prescription data at the time the medication tray (10) accepts the medication filled containers (30), which is then downloaded to the docking station (20). The docking station (20) monitors and reports to third parties, via a network (160), a patient's compliance with various medication treatment regimens. Medication containers (30) are provided with low bit tags (35) that provide container presence information to the docking station (20). The docking station (20) provides visual and/or audio signals regarding prescription data to a patient. The docking station (20) can query patients and appliances regarding patient's medication usage and health status.

Abstract: The invention relates to devices for continuously measuring the concentrations of more than one target analyte. Specifically, the devices comprise a plurality of analyte binding domains, with each domain being capable of specifically and reversibly binding to at least one of the target analytes. The devices further comprise a membrane surrounding these binding domains that is permeable to the target analytes. The devices convey binding information to a detector. The invention also relates to methods of using the devices, including monitoring chronic disease states in an individual.

Abstract: The invention relates to methods and devices for measuring blood glucose levels in a subject, where the methods and devices are designed for exposing a sensing mechanism to interstitial fluid in the subject.

Abstract: A system comprising a medication tray (10) and a docking station (20) for facilitating effective self-management of medication treatment by patients is provided. The medication tray (10) accepts medication filled containers (30) and mates with the docking station (20). The medication tray (10) receives prescription data at the time the medication tray (10) accepts the medication filled containers (30), which is then downloaded to the docking station (20). The docking station (20) monitors and reports to third parties, via a network (160), a patient's compliance with various medication treatment regimens. Medication containers (30) are provided with low bit tags (35) that provide container presence information to the docking station (20). The docking station (20) provides visual and/or audio signals regarding prescription data to a patient. The docking station (20) can query patients and appliances regarding patient's medication usage and health status.

Abstract: An electronic health care management system is provided which collects both subjective and objective information regarding a patient into a clinical patient record, and uses the record to determine evidence-based recommendations. A healthcare provider may decide to implement certain recommendations, and/or provide additional interventions which are collectively implemented using automated support tools. Often, a plan can include follow-up activities which may be automatically scheduled by the electronic health care management system, and may include external scheduling programs and corresponding application-programming interfaces (APIs).

Abstract: A closed loop therapy system for controlling a concentration of a substance, such as blood glucose concentration, in the body of a user. The system and method employ a sensor system that measures a glucose level in the body, a controller that uses the measured glucose levels to generate an output that can be used to automatically or manually control an intradermal insulin infusion system to set a constant or time-varying profile of target blood glucose concentrations in a user, and then infuse an appropriate amount of insulin into the body of the user so as to reach and maintain the target values of the blood glucose concentration.

Abstract: The invention relates to devices for continuously measuring the concentrations of more than one target analyte. Specifically, the devices comprise a plurality of analyte binding domains, with each domain being capable of specifically and reversibly binding to at least one of the target analytes. The devices further comprise a membrane surrounding these binding domains that is permeable to the target analytes. The devices convey binding information to a detector. The invention also relates to methods of using the devices, including monitoring chronic disease states in an individual.

Abstract: A system comprising a medication tray (10) and a docking station (20) for facilitating effective self-management of medication treatment by patients is provided. The medication tray (10) accepts medication filled containers (30) and mates with the docking station (20). The medication tray (10) receives prescription data at the time the medication tray (10) accepts the medication filled containers (30), which is then downloaded to the docking station (20). The docking station (20) monitors and reports to third parties, via a network (160), a patient's compliance with various medication treatment regimens. Medication containers (30) are provided with low bit tags (35) that provide container presence information to the docking station (20). The docking station (20) provides visual and/or audio signals regarding prescription data to a patient. The docking station (20) can query patients and appliances regarding patient's medication usage and health status.

Abstract: The present invention relates to methods and devices for delivering one or more biologically active agents, particularly therapeutic agents, to the intradermal compartment of a subject's skin. The present invention provides an improved method of delivery of biologically active agents, such as therapeutic agents, through lymphatic vasculature accessed by intradermal delivery. Therapeutic agents to be delivered in accordance with the present invention include, but are not limited to, antineoplastic agents, chemotherapeutic agents, antibodies, antibiotics, anti-angiogenesis agents, anti-inflammatory agents, and immunotherapeutic agents. Therapeutic agents delivered in accordance with the present invention have improved bioavailability, including improved systemic distribution and improved delivery to particular tissues.

Abstract: The present invention relates to methods and devices for delivering one or more biologically active agents, particularly a diagnostic agent to the intradermal compartment of a subject's skin. The present invention provides an improved method of delivery of biologically active agents in that it provides among other benefits, rapid uptake into the local lymphatics, improved targeting to a particular tissue, improved bioavailability, improved tissue bioavailability, improved tissue specific kinetics, improved deposition of a pre-selected volume of the agent to be administered, and rapid biological and pharmacodynamics and biological and pharmacokinetics. This invention provides methods for rapid transport of agents through lymphatic vasculature accessed by intradermal delivery of the agent. Methods of the invention are particularly useful for delivery of diagnostic agents.

Abstract: A closed loop therapy system for controlling a concentration of a substance, such as blood glucose concentration, in the body of a user. The system and method employ a sensor system that measures a glucose level in the body, a controller that uses the measured glucose levels to generate an output that can be used to automatically or manually control an intradermal insulin infusion system to set a constant or time-varying profile of target blood glucose concentrations in a user, and then infuse an appropriate amount of insulin into the body of the user so as to reach and maintain the target values of the blood glucose concentration.