Abstract: Bioactive peptides and methods for their use for preventing, treating, and/or reducing the incidence and/or symptoms of an autoimmune disease or disorder that may result from chronic inflammation, damage to B-cells of the pancreas, and other conditions that are implicated by the CD40-CD154 dyad. In particular, small peptides that are capable of interacting with CD40, thereby interfering with the ability of CD40 to interact with CD154, which impacts inflammation, autoimmunity, and disease progression. The use of such peptides in reducing diabetes mellitus, and in particular, the autoimmune inflammatory response that may be a driving factor thereof. Methods and materials for preventing and modulating diabetes mellitus and autoimmune diseases especially in dogs, cats, and horses.

Abstract: A method of automatic path planning for at least one robot within a confined configuration space, the robot including an arm having a plurality of joints and an end effector coupled to the arm. The method includes entering a plurality of process points into a computer, each process point being a location wherein the arm is to be positioned to perform a task, calculating one or more inverse kinematic solutions for each process point, clustering the inverse kinematic solutions into a set of clusters, and generating collision free paths between the clusters in the confined configuration space.

Abstract: System for producing an oxygen-rich gas comprising (a) a primary gas mover including a first and a second compressor, wherein the primary gas mover is characterized by a weight Wp; (b) a drive motor adapted to drive the first and second compressors; (c) a rechargeable power supply characterized by a weight, Wb; and (d) a pressure/vacuum swing adsorption unit adapted to separate the pressurized feed air into an oxygen-rich product at a product flow rate Fp and an oxygen-depleted waste gas, wherein the adsorption unit comprises a plurality of adsorber beds containing an adsorbent and characterized by a total adsorbent weight Wa; and wherein the combined weight, Wt, of the adsorbent, the primary gas mover, and the rechargeable power supply is characterized by the expression 0.75 Fp<Wt<2.02 Fp where Fp is in liters per min (at 23° C. and 1 atma pressure), and Wa, Wp, and Wb are in pounds.

Abstract: Portable medical oxygen concentrator comprising an air separation system adapted to recover oxygen from air; a bottom platform and a shell having an outer wall, wherein the shell is detachably connected to the bottom platform, wherein the shell and bottom platform define an enclosed volume when the shell is connected to the bottom platform, and wherein the air separation system is disposed in the enclosed volume; and one or more rechargeable batteries detachably connected to the outer wall of the shell and adapted to provide power to drive the air separation system. The air separation system may comprises a pressure swing adsorption system having two or more adsorbent columns and a rotary valve for directing gas flow sequentially to, from, and among the columns. A base assembly attached to the bottom platform may be adapted to support the two or more adsorbent columns and the rotary valve.

Abstract: Rotary valve comprising (a) a rotor having a rotor face rotatable about an axis perpendicular to the rotor face, a plurality of openings, and at least one passage connecting at least one pair of the plurality of openings; (b) a stator having a stator face in sealing contact with the rotor face to form a planar rotary valve seal with an outer periphery, a plurality of openings in the stator face that are connected to respective passages through the stator, and wherein at least one of the passages through the stator is a stator vacuum passage directly connected to a vacuum pump; (c) a sealed valve chamber having an interior volume contiguous with the outer periphery of the rotary valve seal, which chamber is sealed from the atmosphere surrounding the rotary valve; and (d) a vacuum vent passage connected to the sealed valve chamber.

Abstract: The present invention provides a scroll pump device comprising external and internal scroll members, and wherein the scroll pump device is separated into inner and outer zones. The flow streams in the two zones are kept separate, and each stream may have different chemical compositions and flow rates. The scroll pump system can provide both vacuum and pressure flow streams in a compact lightweight package, and may be used for the separation and concentration of oxygen from atmospheric air, for use, inter alia, in portable medical systems.

Abstract: System for producing an oxygen-rich gas comprising (a) a primary gas mover including a first and a second compressor, wherein the primary gas mover is characterized by a weight Wp; (b) a drive motor adapted to drive the first and second compressors; (c) a rechargeable power supply characterized by a weight, Wb; and (d) a pressure/vacuum swing adsorption unit adapted to separate the pressurized feed air into an oxygen-rich product at a product flow rate Fp and an oxygen-depleted waste gas, wherein the adsorption unit comprises a plurality of adsorber beds containing an adsorbent and characterized by a total adsorbent weight Wa; and wherein the combined weight, Wt, of the adsorbent, the primary gas mover, and the rechargeable power supply is characterized by the expression 0.75 Fp<Wt<2.02 Fp where Fp is in liters per min (at 23° C. and 1 atma pressure), and Wa, Wp, and Wb are in pounds.

Abstract: Oxygen concentrator system comprising a portable oxygen generator unit adapted to generate a non-humidified oxygen-rich gas and a stationary base unit adapted to generate a humidified oxygen-rich gas, wherein the portable oxygen generator unit and the stationary base are adapted for operation in a coupled mode and an uncoupled mode. The portable oxygen generator unit includes a first flow coupling adapted to receive the humidified oxygen-rich gas when operating in the coupled mode, piping means adapted to combine the non-humidified oxygen-rich gas and the humidified oxygen-rich gas to form a humidified oxygen-rich gas product, and an oxygen-rich gas product delivery port. The stationary base unit is adapted to recharge a rechargeable power supply system in the portable oxygen generator unit when the units are coupled.

Abstract: Oxygen generation system comprising a portable oxygen generator unit including a portable air separation device for the generation of an oxygen-rich gas, a primary gas pump including means to supply air to the portable air separation device, a primary motor to drive the gas pump, a rechargeable power supply to drive the motor, connector means adapted to deliver power to the rechargeable power supply, flow coupling means to transfer the oxygen-rich gas from the portable oxygen generator unit, and a first oxygen-rich gas product discharge port. The system also includes a stationary base unit adapted to couple with the portable oxygen generator unit, wherein the stationary base unit comprises a stationary power supply system including connector means adapted to recharge the rechargeable power supply in the portable oxygen generator unit, flow coupling means to receive the oxygen-rich gas from the portable oxygen generator unit, and an optional second oxygen-rich gas product discharge port.

Abstract: A basketball goal and pole is provided of the type permitting the height of the basketball goal above a playing surface to be adjusted. The adjustable basketball goal comprises: a vertical pole having a plurality of rails formed on the outside thereof running along the longitudinal axis of the pole, a crank assembly having a rotatable reel fastened to the pole beneath the rails, a pulley assembly having a grooved wheel fastened to the pole atop the rails, a collar having an interior surface forming trackways slidably mounted on the rails and movable between the crank assembly and the pulley assembly, a basketball goal extending upwardly and outwardly from the collar, and a cable connected to the reel and threaded over the grooved wheel and connected to the collar for moving the collar between the crank assembly and the pulley assembly.