Abstract: An imaging and navigation system is disclosed herein. The imaging and navigation system includes a computer and an ultrasonic imaging device disposed at least partially within an ultrasound catheter. The ultrasonic imaging device is connected to the computer and is adapted to obtain a generally real time three-dimensional image. The imaging and navigation system also includes a tracking system connected to the computer. The tracking system is adapted to estimate a position of a medical instrument. The imaging and navigation system also includes a display connected to the computer. The display is adapted to depict the generally real time three-dimensional image from the ultrasonic imaging device and to graphically convey the estimated position of the medical instrument.

Abstract: A flexible interconnect circuit includes a plurality of substantially flat flex circuits. Each flex circuit has a length substantially greater than its corresponding width. The plurality of flex circuits are folded parallel to their long axes and configured together to provide a layered flex interconnect circuit structure in which at least one ground flex circuit is interposed with one or more signal flex circuits.

Abstract: Migration of air through a flanged connection into piping containing a gas under negative pressure is prevented by disposing concentric inner and outer gaskets between the flange faces, so as to form an annular chamber into which a blanketing gas is introduced at a pressure higher than atmospheric. Air tending to migrate through the outer gasket is blocked by the higher-pressure blanketing gas in the annular chamber. The blanketing gas pressure is maintained at a level higher than atmospheric notwithstanding any fugitive emissions through the outer gasket. The annular chambers of multiple flanged connections may be interconnected to blanket multiple flanged connections using a single source of blanketing gas. The blanketing gas may be the same type as the gas under negative pressure. In sour service applications, an inert blanketing gas may be used to prevent leakage of sour gas to atmosphere through flanged connections.

Abstract: In a system for optimizing natural gas production in response to real-time variations in wellbore parameters, a PLC or other wellsite intelligence technology is used to monitor liquid and gas production from the wellbore under friction-loaded conditions. Using baseline production data obtained during production tests, the PLC determines and initiates the appropriate operating mode for the wellbore to optimize a selected production criterion to suit measured wellbore parameters. The operating mode either a continuous clean-out mode, in which gas is continuously injected into the wellbore to control liquid loading, or an intermittent clean-out, in which liquid loading is regulated by intermittent gas injection. In preferred embodiments, the system uses bladder-type control valves having upstream and downstream solenoids, to control production tubing flow rate within a range between upper and lower set points.

Abstract: Provided herein is an ultrasound probe comprising a probe housing defining a distal end, an ultrasonic transducer array disposed within the probe housing and rotatable within said probe housing, an acoustically neutral structure bonded to a surface of the ultrasonic transducer array by an adhesive, a motor coupled to the ultrasonic transducer array, the motor being configured to rotate the ultrasonic transducer array in order to image a three-dimensional volume; and an acoustic coupling fluid disposed within free volume of the probe housing. Also provided is a method of manufacturing.

Abstract: An ultrasound catheter housing with electromagnetic shielding properties and methods of manufacturing is provided. The ultrasound catheter housing comprises a an inner thin wall polymer tube extruded using an ultrasonically transparent polymer, a thin metalized layer deposited on the outer surface of the inner tube, and an outer thin wall polymer tube, which may be the same or a different ultrasonically transparent material. In another embodiment an ultrasound catheter comprising the ultrasound catheter housing is provided.

Abstract: A transducer assembly is provided including a transducer array comprising a plurality ‘M’ of transducer elements and a sub-aperture processor comprising a plurality ‘P’ of input channels and an output channel. The plurality ‘P’ of input channels is coupled to the ‘M’ transducer elements and a plurality ‘R’ of switching elements in operative association with the output channel of the sub-aperture processor to switchably couple the output channel to at least one of a plurality of ‘N’ system channels.

Abstract: A system for imaging and providing therapy to one or more regions of interest is presented. The system includes an imaging and therapy catheter configured to image an anatomical region to facilitate assessing need for therapy in one or more regions within the anatomical region and delivering therapy to the one or more regions of interest within the anatomical region. The catheter includes a therapy device having a plurality of independently controllable therapy elements. The independence of the therapy elements is exploited when multiple regions are to receive therapy simultaneously or at a given catheter position within a subject.

Abstract: A device and a method for sealing a micromotor with an optional associated gearbox are disclosed where, in one aspect of the present invention, a catheter tip comprises: a micromotor; an ultrasound imaging transducer; a gearbox mechanically coupled to the micromotor, the gearbox having a rotatable portion mechanically coupled to the ultrasound imaging transducer array; and a moisture barrier disposed so as to reduce or prevent acoustic coupling fluid from entering both the gearbox and the micromotor.

Abstract: An cable connector system is provided. A receptacle for the connector system includes a pair of opposing compression plates and at least one rotatable member configured to move the opposing compression plates as the rotatable member rotates. The compression plates cause contact with a portion of the plug inserted therebetween.

Abstract: A composite structure of a backing material with enhanced conductivity for use in a transducer is presented. The composite structure includes a plurality of layers of backing material alternatingly arranged with a plurality of thermal conductive elements, wherein the plurality of thermal conductive elements are configured to transfer heat from a center of the transducer to a plurality of points on the composite structure of backing material.

Abstract: An cable connector system is provided. A receptacle for the connector system includes a pair of opposing compression plates and at least one rotatable member configured to move the opposing compression plates as the rotatable member rotates. The compression plates cause contact with a portion of the plug inserted therebetween.

Abstract: A composite structure of a z-axis interconnect is presented. The composite structure includes a plurality of layers of backing material alternatingly arranged between a plurality of interconnect layers, where the plurality of interconnect layers is configured to facilitate coupling the composite structure of the z-axis interconnect to a transducer array, where the composite structure of z-axis interconnect is configured for use in an invasive probe.

Abstract: An ultrasonic imaging system and method for acquiring three-dimensional (3D) image data sets are provided. The system comprises a transducer array with a given range of motion adapted to obtain a plurality of 3D image data sets of a region of interest and a processor coupled to the transducer array adapted to receive image data sets from the transducer array and to correct for spatially varying errors induced by motion of the transducer array.

Abstract: A sub-aperture transceiver system for an ultrasound probe includes a signal processor, receive signal connections connecting the signal processor to a receive aperture comprising acoustic transceiver elements, and transmit signal connections coupled to a transmit aperture that includes at least one acoustic transceiver element multiplexed with the receive aperture.

Abstract: A system for imaging and providing therapy to one or more regions of interest is presented. The system includes an imaging and therapy catheter configured to image an anatomical region to facilitate assessing need for therapy in one or more regions within the anatomical region and delivering therapy to the one or more regions of interest within the anatomical region. In addition, the system includes a medical imaging system operationally coupled to the catheter and having a display area and a user interface area, wherein the medical imaging system is configured to facilitate defining a therapy pathway to facilitate delivering therapy to the one or more regions of interest.

Abstract: The present invention relates to a method for making an integrated sensor comprising providing a sensor array fabricated on a top surface of a bulk silicon wafer having a top surface and a bottom surface, and comprising a plurality of sensors fabricated on the top surface of the bulk silicon wafer. The method further comprises coupling an SOI wafer to the top surface of the bulk silicon wafer, thinning the back surface of the bulk silicon wafer, coupling a plurality of integrated circuit die to the back surface of the bulk silicon wafer, and removing the SOI wafer from the top surface of the bulk silicon wafer.

Abstract: A method for implementing an imaging and navigation system to perform a medical procedure such as cardiac ablation is disclosed herein. The a method includes implementing an ultrasonic imaging device to provide a generally real time three-dimensional patient image, identifying a target site on the generally real time three-dimensional patient image, directing a medical instrument to the target site using a tracking system, and performing a medical procedure at the target site.

Abstract: An imaging catheter assembly is presented. The imaging catheter assembly includes an imaging catheter which includes an imaging catheter tip. Further, the imaging catheter assembly includes a fluid reservoir connected to the imaging catheter and configured to deliver fluid through a proximal end of the imaging catheter tip. The imaging catheter assembly also includes a release mechanism configured to cause delivery of the fluid to the imaging catheter tip when activated.

Abstract: An imaging and navigation system is disclosed herein. The imaging and navigation system includes a computer and an ultrasonic imaging device disposed at least partially within an ultrasound catheter. The ultrasonic imaging device is connected to the computer and is adapted to obtain a generally real time three-dimensional image. The imaging and navigation system also includes a tracking system connected to the computer. The tracking system is adapted to estimate a position of a medical instrument. The imaging and navigation system also includes a display connected to the computer. The display is adapted to depict the generally real time three-dimensional image from the ultrasonic imaging device and to graphically convey the estimated position of the medical instrument.