Patents by Inventor Glennda Smithson

Glennda Smithson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Novel proteins and nucleic acids encoding same
    Publication number: 20030216545
    Abstract: Disclosed herein are nucleic acid sequences that encode G-coupled protein-receptor related polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
    Type: Application
    Filed: September 27, 2001
    Publication date: November 20, 2003
    Inventors: Kimberly A. Spytek, Stacie Casman, Muralidhara Padigaru, Kevin S. Dickson, Corine Vernet, Steven K. Spaderna, Suresh G. Shenoy, Valerie Gerlach, Karen Ellerman, Shlomit Edinger, John R. MacDougall, Glennda Smithson, Li Li, Uriel M. Malyankar, Sarah Taylor, Erik Gunther, Velizar T. Tchernev
  • Novel polypeptides and nucleic acids encoding same
    Publication number: 20030216308
    Abstract: The present invention provides novel isolated NOVX polynucleotides and polypeptides encoded by the NOVX polynucleotides. Also provided are the antibodies that immunospecifically bind to a NOVX polypeptide or any derivative, variant, mutant or fragment of the NOVX polypeptide, polynucleotide or antibody. The invention additionally provides methods in which the NOVX polypeptide, polynucleotide and antibody are utilized in the detection and treatment of a broad range of pathological states, as well as to other uses.
    Type: Application
    Filed: June 17, 2002
    Publication date: November 20, 2003
    Inventors: David W. Anderson, Xiaojia (Sasha) Guo, Vladimir Y. Gusev, John L. Herrmann, Li Li, Peter S. Mezes, Muralidhara Padigaru, Meera Patturajan, Carol E. A. Pena, Luca Rastelli, Richard A. Shimkets, Glennda Smithson, Steven K. Spaderna, Raymond J. Taupier, Corine A.M. Vernet
  • Novel proteins and nucleic acids encoding same
    Publication number: 20030216304
    Abstract: Disclosed herein are nucleic acid sequences that encode G-coupled protein-receptor related polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
    Type: Application
    Filed: April 27, 2001
    Publication date: November 20, 2003
    Inventors: Muralidhara Padigaru, Vishnu Mishra, Kimberly A. Spytek, William M. Grosse, Edward S. Szekeres, John P. Alsobrook, Catherine E. Burgess, Stacie J. Casman, Denise M. Lepley, Esha A. Gangolli, John R. MacDougall, Glennda Smithson
  • Proteins and nucleic acids encoding same
    Publication number: 20030212256
    Abstract: Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
    Type: Application
    Filed: October 16, 2001
    Publication date: November 13, 2003
    Inventors: Shlomit R. Edinger, Valerie Gerlach, John R. MacDougall, Uriel M. Malyankar, Glennda Smithson, Isabelle Millet, John A. Peyman, David J. Stone, Erik Gunther, Karen Ellerman, Richard A. Shimkets, Muralidhara Padigaru, Xiaojia Guo, Meera Patturajan, Raymond J. Taupier, Catherine E. Burgess, Bryan D. Zerhusen, Ramesh Kekuda, Kimberly A. Spytek, Esha A. Gangolli, Elma R. Fernandes, Linda Gorman
  • Novel proteins and nucleic acids encoding same
    Publication number: 20030211485
    Abstract: Disclosed herein are nucleic acid sequences that encode G-coupled protein-receptor related polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
    Type: Application
    Filed: May 29, 2002
    Publication date: November 13, 2003
    Inventors: Valerie L. Gerlach, John R. MacDougall, David J. Stone, Glennda Smithson, Muralidhara Padigaru, Catherine Burgess, Corine Vernet, Elma Fernandes, Richard A. Shimkets, Velizar T. Tchernev, Vishnu Mishra, Stacie Casman, Kimberly A. Spytek, Bryan Zerhusen
  • Novel proteins and nucleic acids encoding same
    Publication number: 20030211985
    Abstract: Disclosed herein are nucleic acid sequences that encode G-coupled protein-receptor related polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
    Type: Application
    Filed: July 18, 2001
    Publication date: November 13, 2003
    Inventors: Bryan D. Zerhusen, Muralidhara Padigaru, Li Li, Catherine E. Burgess, Stacie J. Casman, Kimberly A. Spytek, Vishnu S. Mishra, Sarah Taylor, Suresh G. Shenoy, Corine A.M. Vernet, Valerie Gerlach, Karen Ellerman, John R. MacDougall, David J. Stone, Glennda Smithson, William M. Grosse, John P. Alsobrook, Denise M. Lepley, Velizar T. Tchrnev, Bruce E. Taillon
  • Novel proteins and nucleic acids encoding same
    Publication number: 20030212255
    Abstract: Disclosed herein are nucleic acid sequences that encode G-coupled protein-receptor related polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and TRA 1536859v1 antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
    Type: Application
    Filed: July 25, 2001
    Publication date: November 13, 2003
    Inventors: Muralidhara Padigaru, Peter Mezes, Vishnu Mishra, Catherine Burgess, Stacie Casman, William M. Grosse, John P. Alsobrook, Denise M. Lepley, Valerie L. Gerlach, John R. MacDougall, Glennda Smithson
  • Novel human proteins, polynucleotides encoding them and methods of using the same
    Publication number: 20030212257
    Abstract: Disclosed are polypeptides and nucleic acids encoding same. Also disclosed are vectors, host cells, antibodies and recombinant methods for producing the polypeptides and polynucleotides, as well as methods for using same.
    Type: Application
    Filed: April 2, 2002
    Publication date: November 13, 2003
    Inventors: Kimberly A. Spytek, Li Li, Shlomit R. Edinger, Karen Ellerman, David J. Stone, Uriel M. Malyankar, Richard A. Shimkets, Xiaojia Sasha Guo, David W. Anderson, Meera Patturajan, Constance Berghs, Valerie Gerlach, Vladimir Y. Gusev, Ramesh Kekuda, Linda Gorman, Bryan D. Zerhusen, Jason C. Baumgartner, Velizar T. Tchernev, Corine A.M. Vernet, Glennda Smithson, Suresh G. Shenoy, Xiaohong Liu, John R. MacDoughall
  • Novel antibodies that bind to antigenic polypeptides, nucleic acids encoding the antigens, and methods of use
    Publication number: 20030208039
    Abstract: Disclosed herein are nucleic acid sequences that encode polypeptides. Also disclosed are antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids, polypeptides, or antibodies, or fragments thereof.
    Type: Application
    Filed: March 8, 2002
    Publication date: November 6, 2003
    Inventors: Muralidhara Padigaru, Suresh G. Shenoy, Remesh Kekuda, Vladimir Gusev, Pascale F-J Pochart, Mei Zhong, Luca Rastelli, Peter D. Mezes, Glennda Smithson, Xiaojia Sasha Guo, Valerie Gerlach, Stacie J. Casman, Ferenc L. Boldog, Li Li, Bryan D. Zerhusen, Velizar T. Tchernev, Esha A. Gangolli, Corine A.M. Vernet, Carol E. A. Pena, Catherine E. Burgess, Xiaohong Liu, Kimberly A. Spytek, Linda Gorman, Steven K. Spaderna, Edward Z. Voss, Uriel M. Malyankar, David W. Anderson, Meera Patturajan, Charles E. Miller, Raymond J. Taupier
  • Proteins and nucleic acids encoding same
    Publication number: 20030203843
    Abstract: Disclosed are polypeptides and nucleic acids encoding same. Also disclosed are vectors, host cells, antibodies and recombinant methods for producing the polypeptides and polynucleotides, as well as methods for using same.
    Type: Application
    Filed: April 11, 2002
    Publication date: October 30, 2003
    Inventors: Carol E. A. Pena, Xiaojia (Sasha) Guo, Richard A. Shimkets, Muralidhara Padigaru, Ramesh Kekuda, Kimberly A. Spytek, Fuad Mehraban, James Newman Topper, Uriel M. Malyankar, Scott Michael Wasserman, Shlomit R. Edinger, Glennda Smithson, Erik Gunther, Laszlo Komuves
  • Novel polypeptides and nucleic acids encoding same
    Publication number: 20030199465
    Abstract: The present invention provides novel isolated NOVX polynucleotides and polypeptides encoded by the NOVX polynucleotides. Also provided are the antibodies that immunospecifically bind to a NOVX polypeptide or any derivative, variant, mutant or fragment of the NOVX polypeptide, polynucleotide or antibody. The invention additionally provides methods in which the NOVX polypeptide, polynucleotide and antibody are utilized in the detection and treatment of a broad range of pathological states, as well as to other uses.
    Type: Application
    Filed: April 22, 2002
    Publication date: October 23, 2003
    Inventors: Uriel M. Malyankar, Velizar T. Tchernev, Muralidhara Padigaru, Raymond J. Taupier, Kimberly A. Spytek, Xiaojia (Sasha) Guo, Steven K. Spaderna, Ferenc L. Boldog, Valerie Gerlach, Karen Ellerman, John R. MacDougall, Glennda Smithson
  • Noval human proteins, polynucleotides encoding them and methods of using the same
    Publication number: 20030198958
    Abstract: The invention provides polypeptides, designated herein as POLYX polypeptides, as well as polynucleotides encoding POLYX polypeptides, and antibodies that immunospecifically-bind to POLYX polypeptide or polynucleotide, or derivatives, variants, mutants, or fragments thereof. The invention additionally provides methods in which the POLYX polypeptide, polynucleotide, and antibody are used in the detection, prevention, and treatment of a broad range of pathological states.
    Type: Application
    Filed: March 13, 2002
    Publication date: October 23, 2003
    Inventors: Richard A. Shimkets, Elma Fernandes, John L. Herrmann, Xiaohong Liu, Meijia Yang, Ferenc L. Boldog, Glennda Smithson, Luca Rastelli
  • Novel proteins and nucleic acids encoding same
    Publication number: 20030198955
    Abstract: Disclosed herein are nucleic acid sequences that encode G-coupled protein-receptor related polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
    Type: Application
    Filed: December 19, 2001
    Publication date: October 23, 2003
    Inventors: Li Li, Muralidhara Padigaru, Robert A. Ballinger, Ramesh Kekuda, Steven D. Colman, Kimberly A. Spytek, Stacie J. Casman, Shlomit R. Edinger, Valerie Gerlach, Paul Sciore, Glennda Smithson, John A. Peyman, John R. MacDougall, David J. Stone, Corine A.M. Vernet, Suresh G. Shenoy, Erik Gunther, Isabelle Millet, Velizar T. Tchernev, David W. Anderson, Vladimir Y. Gusev, Uriel M. Malyankar, Haihong Zhong, Karen Ellerman, Adam R. Wolenc
  • Novel proteins and nucleic acids encoding same
    Publication number: 20030195335
    Abstract: Disclosed herein are nucleic acid sequences that encode G-coupled protein-receptor related polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
    Type: Application
    Filed: January 11, 2002
    Publication date: October 16, 2003
    Inventors: William M. Grosse, Edward S. Szekeres, Stacie Casman, John P. Alsobrook, Catherine E. Burgess, Muralidhara Padigaru, Sarah Taylor, Velizar T. Tchernev, Kimberly A. Spytek, Li Li, Suresh Shenoy, Ramesh Kekuda, Esha A. Gangolli, David J. Stone, Glennda Smithson, John R. MacDougall
  • Novel antibodies that bind to antigenic polypeptides, nucleic acids encoding the antigens, and methods of use
    Publication number: 20030185815
    Abstract: Disclosed herein are nucleic acid sequences that encode polypeptides. Also disclosed are antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids, polypeptides, or antibodies, or fragments thereof.
    Type: Application
    Filed: April 2, 2002
    Publication date: October 2, 2003
    Inventors: Muralidhara Padigaru, Suresh G. Shenoy, Ramesh Kekuda, Luca Rastelli, Peter D. Mezes, Glennda Smithson, Xiaojia Guo, Valerie Gerlach, Stacie J. Casman, Ferenc L. Boldog, Li Li, Bryan D. Zerhusen, Velizar T. Tchernev, Esha A. Gangolli, Corine A. M. Vernet, Kimberly A. Spytek, Uriel M. Malyankar, Meera Patturajan, Charles E. Miller, Raymond J. Taupier, Melvyn P. Heyes, Jingfang Ju, John A. Peyman, Elina Catterton, John R. MacDougall, Shlomit R. Edinger, David J. Stone, Ann Mazur
  • Antisense modulation of protein expression
    Publication number: 20030176385
    Abstract: Antisense compounds, compositions and methods are provided for modulating the expression of H-Ras, WNT-7B, acetylglucosaminyltransferase, voltage-gated K channel, IL-8, ion transport, Map3K8 and Thymidine kinase. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding H-Ras, WNT-7B, acetylglucosaminyltransferase, voltage-gated K channel, IL-8, ion transport, Map3K8 and Thymidine kinase. Methods of using these compounds for modulation of H-Ras, WNT-7B, acetylglucosaminyltransferase, voltage-gated K channel, IL-8, ion transport, Map3K8 and Thymidine kinase.expression and for treatment of diseases associated with expression of H-Ras, WNT-7B, acetylglucosaminyltransferase, voltage-gated K channel, 1L-8, ion transport, Map3KS and Thymidine kinase are provided.
    Type: Application
    Filed: November 27, 2002
    Publication date: September 18, 2003
    Inventors: Jingfang Ju, Chunli Huang, Haihong Zhong, Jan Fredrik Simons, Bruce E. Taillon, John S. Chant, John A. Peyman, Glennda Smithson, Isabelle Millet
  • Novel polynucleotides and polypeptides encoded thereby
    Publication number: 20030170838
    Abstract: Disclosed herein are nucleic acid sequences that encode Wnt, zinc transporter, mitsugumin29, slit-3, LRR/GPCR, major histocompatability complex enhancer protein MAD3, interleukin 9, 5-hydroxytryptamine receptor, and thioredoxin related polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
    Type: Application
    Filed: September 17, 2001
    Publication date: September 11, 2003
    Inventors: Vishnu S. Mishra, Kimberly Ann Spytek, Raymond J. Taupier, Corine A. Vernet, Steven D. Colman, Linda Gorman, Velizar T. Tchernev, Uriel M. Malyankar, Suresh Shenoy, Muralidhara Padigaru, Valerie L. Gerlach, John R. MacDougall, Glennda Smithson, Isabelle Millet, John Peyman, David Stone, Erik Gunther, Karen Ellerman, Li Li, Luca Rastelli, Bryan Zerhusen
  • Proteins and nucleic acids encoding same
    Publication number: 20030170630
    Abstract: Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
    Type: Application
    Filed: December 21, 2001
    Publication date: September 11, 2003
    Inventors: John P. Alsobrook, Velizar T. Tchernev, Xiaohong Liu, Kimberly A. Spytek, Bryan D. Zerhusen, Meera Patturajan, Denise M. Lepley, Catherine E. Burgess, Richard A. Shimkets, William M. Grosse, Edward S. Szekeres, Corine A.M. Vernet, Li Li, Stacie J. Casman, Ference L. Boldog, Linda Gorman, Esha A. Gangolli, Elma R. Fernandes, Danier K. Rieger, Shlomit R. Edinger, Erik Gunther, Isabelle Millet, Paul Sciore, Karen Ellerman, John R. MacDougall, Glennda Smithson
  • Novel GPCR-like proteins and nucleic acids encoding same
    Publication number: 20030165858
    Abstract: Disclosed herein are nucleic acid sequences that encode G-coupled protein-receptor related polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
    Type: Application
    Filed: December 18, 2001
    Publication date: September 4, 2003
    Inventors: Muralidhara Padigaru, Valerie L. Gerlach, Glennda Smithson, David Stone, Ruey Bing-Yang, Pamela B. Conley, Matthew Hart, James E. Tomlinson, James Newman Topper, Ramesh Kekuda, Stacie J. Casman, John R. MacDougall, Shlomit R. Edinger
  • Novel secreted proteins and polynucleotides encoding them
    Publication number: 20030152939
    Abstract: The present invention provides novel isolated polypeptides, a fragment of any of them, polynucleotides encoding them and antibodies that immunospecifically bind to them. The invention additionally provides several methods in which these proteins, polynucleotides and antibodies are used in methods of detection and methods of treatment are also disclosed. These methods of detection and treatment are directed to a broad range of pathological states.
    Type: Application
    Filed: April 9, 2002
    Publication date: August 14, 2003
    Inventors: Glennda Smithson, Bryan D. Zerhusen, Mei Zhong, Nikolai V. Khramtsov, Li Li, Vladimir Y. Gusev, Muralidhara Padigaru, David W. Anderson, Richard A. Shimkets