Patents by Inventor Gloria Astrid Limb

Gloria Astrid Limb has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHOD FOR THE PRODUCTION OF MÜLLER CELLS AND CELL PRODUCT
    Publication number: 20220370504
    Abstract: The present invention relates to a novel process of producing therapeutic GMP grade Müller cells and Miller cells obtainable therefrom, derived from stem cells using products that are free of animal-derived components. The Müller cells are suitable for treatment of eye disease, including glaucoma. There is also provided a cell culture medium.
    Type: Application
    Filed: October 30, 2020
    Publication date: November 24, 2022
    Inventors: Gloria Astrid LIMB, Peng Tee KHAW, Karen EASTLAKE, Celia MURRAY-DUNNING, Carla Patricia PINTO DE CARVALHO
  • Transplantation of cells expressing markers for photoreceptor cells and retinal ganglion cells induced from Müller stem cells
    Patent number: 8691207
    Abstract: A method for the production of retinal cells, useful in transplantation therapy, comprises: (i) obtaining one or more mammalian adult Müller cells; and (ii) culturing the cells in the presence of an extracellular matrix protein and a growth factor to thereby induce dedifferentiation of the Müller cells into a progenitor phenotype.
    Type: Grant
    Filed: December 30, 2011
    Date of Patent: April 8, 2014
    Assignee: The Institute of Ophthalmology
    Inventors: Gloria Astrid Limb, Peng Tee Khaw
  • Muller cells de-differentiated to cells expressing markers of neural cell progenitors
    Patent number: 8173426
    Abstract: A method for the production of retinal cells, useful in transplantation therapy, comprises: (i) obtaining one or more mammalian adult Müller cells; and (ii) culturing the cells in the presence of an extracellular matrix protein and a growth factor to thereby induce dedifferentiation of the Müller cells into a progenitor phenotype.
    Type: Grant
    Filed: December 3, 2004
    Date of Patent: May 8, 2012
    Assignee: The Institute of Ophthalmology
    Inventors: Gloria Astrid Limb, Peng Tee Khaw
  • MULLER STEM CELLS
    Publication number: 20120100215
    Abstract: A method for the production of retinal cells, useful in transplantation therapy, comprises: (i) obtaining one or more mammalian adult Müller cells; and (ii) culturing the cells in the presence of an extracellular matrix protein and a growth factor to thereby induce dedifferentiation of the Müller cells into a progenitor phenotype.
    Type: Application
    Filed: December 30, 2011
    Publication date: April 26, 2012
    Applicant: THE INSTITUTE OF OPHTHALMOLOGY
    Inventors: GLORIA ASTRID LIMB, Peng Tee Khaw