Patents by Inventor Gloria Coruzzi
Gloria Coruzzi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230078124Abstract: Provided are machine learning methods for identifying genes that affect plant properties. Also provided are plant cell sand plants comprising genetic modifications that improve plant nitrogen utilization and increased biomass. Methods of making the modified plant cells and plants are also provided.Type: ApplicationFiled: August 10, 2022Publication date: March 16, 2023Inventors: Gloria Coruzzi, Chia-Yi Cheng
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Publication number: 20190194677Abstract: Plant genes regulated by transcription factors that control the gene network response to an environmental perturbation or signal are described. This class of genes responds to the perturbation of a transcription factor and the signal it transduces, but surprisingly, without stable binding of the transcription factor. These genes represent members of the “dark matter” of metabolic regulatory circuits. The invention involves the transgenic manipulation of these “response genes” and/or the genes encoding their regulatory transcription factors in plants so that their respective gene products are either overexpressed or underexpressed in the plant in order to confer a desired phenotype. The invention also relates to a rapid technique named “TARGET” (Transient Assay Reporting Genome-wide Effects of Transcription factors) for determining such “response genes” and their transcription factors by perturbation of the expression of the transcription factors of interest in protoplasts of any plant species.Type: ApplicationFiled: December 6, 2018Publication date: June 27, 2019Inventors: Gloria Coruzzi, Kenneth Birnbaum, Bastiaan Bargmann, Gabriel Krouk
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Publication number: 20180127769Abstract: Plant genes regulated by transcription factors that control the gene network response to an environmental perturbation or signal are described. This class of genes responds to the perturbation of a transcription factor and the signal it transduces, but surprisingly, without stable binding of the transcription factor. These genes represent members of the “dark matter” of metabolic regulatory circuits. The invention involves the transgenic manipulation of these “response genes” and/or the genes encoding their regulatory transcription factors in plants so that their respective gene products are either overexpressed or underexpressed in the plant in order to confer a desired phenotype. The invention also relates to a rapid technique named “TARGET” (transient assay reporting genome-wide effects of transcription factors) for determining such “response genes” and their transcription factors by perturbation of the expression of the transcription factors of interest in protoplasts of any plant species.Type: ApplicationFiled: February 5, 2016Publication date: May 10, 2018Inventors: Gloria CORUZZI, Kenneth BIRNBAUM, Bastiaan BARGMANN, Gabriel KROUK, Manpreet KATARI, Mariana OBERTELLO
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Publication number: 20170240914Abstract: Provided herein are compositions and methods for producing transgenic plants. In specific embodiments, transgenic plants comprise a construct comprising a polynucleotide encoding CCA1, GLK1 or bZIP1, operably linked to a plant-specific promote, wherein the CCA1, GLK1 or bZIP1 is ectopically overexpressed in the transgenic plants, and wherein the promoter is optionally a constitutive or inducible promoter. In other embodiments, transgenic plants in which express a lower level of CCA1, GLK1 or bZIP1 are provided. Also provided herein are commercial products (e.g., pulp, paper, paper products, or lumber) derived from the transgenic plants (e.g., transgenic trees) produced using the methods provided herein.Type: ApplicationFiled: October 7, 2016Publication date: August 24, 2017Applicant: New York UniversityInventors: Gloria Coruzzi, Rodrigo A. Gutierrez, Damion C. Nero
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Patent number: 9551002Abstract: Provided herein are compositions and methods for producing transgenic plants. In specific embodiments, transgenic plants comprise a construct comprising a polynucleotide encoding microRNA167 (miR167), or precursor thereof, operably linked to a plant pericycle-specific promote, wherein the miR167 is ectopically overexpressed in the transgenic plants, and wherein the promoter is optionally a constitutive or inducible promoter. In some embodiments, the transgenic plant has an improved agronomic or nutritional characteristic when cultivated in nitrogen-rich conditions as compared to a wild type plant cultivated in the same conditions. Also provided herein are commercial products (e.g., pulp, paper, paper products, or lumber) derived from the transgenic plants (e.g., transgenic trees) produced using the methods provided herein.Type: GrantFiled: December 19, 2013Date of Patent: January 24, 2017Assignee: New York UniversityInventors: Gloria Coruzzi, Kenneth D. Birnbaum, Rodrigo A. Gutierrez, Miriam Gifford
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Patent number: 9464296Abstract: Provided herein are compositions and methods for producing transgenic plants. In specific embodiments, transgenic plants comprise a construct comprising a polynucleotide encoding CCA1, GLK1 or bZIP1, operably linked to a plant-specific promote, wherein the CCA1, GLK1 or bZIP1 is ectopically overexpressed in the transgenic plants, and wherein the promoter is optionally a constitutive or inducible promoter. In other embodiments, transgenic plants in which express a lower level of CCA1, GLK1 or bZIP1 are provided. Also provided herein are commercial products (e.g., pulp, paper, paper products, or lumber) derived from the transgenic plants (e.g., transgenic trees) produced using the methods provided herein.Type: GrantFiled: March 9, 2011Date of Patent: October 11, 2016Assignee: New York UniversityInventors: Gloria Coruzzi, Rodrigo A. Gutierrez, Damion C. Nero
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Publication number: 20150067923Abstract: Plant genes regulated by transcription factors that control the gene network response to an environmental perturbation or signal are described. This class of genes responds to the perturbation of a transcription factor and the signal it transduces, but surprisingly, without stable binding of the transcription factor. These genes represent members of the “dark matter” of metabolic regulatory circuits. The invention involves the transgenic manipulation of these “response genes” and/or the genes encoding their regulatory transcription factors in plants so that their respective gene products are either overexpressed or underexpressed in the plant in order to confer a desired phenotype. The invention also relates to a rapid technique named “TARGET” (Transient Assay Reporting Genome-wide Effects of Transcription factors) for determining such “response genes” and their transcription factors by perturbation of the expression of the transcription factors of interest in protoplasts of any plant species.Type: ApplicationFiled: August 12, 2014Publication date: March 5, 2015Applicant: New York UniversityInventors: Gloria Coruzzi, Kenneth Birnbaum, Bastiaan Bargmann, Gabriel Krouk
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Publication number: 20140283217Abstract: Provided herein are compositions and methods for producing transgenic plants. In specific embodiments, transgenic plants comprise a construct comprising a polynucleotide encoding microRNA167 (miR167), or precursor thereof, operably linked to a plant pericycle-specific promote, wherein the miR167 is ectopically overexpressed in the transgenic plants, and wherein the promoter is optionally a constitutive or inducible promoter. In some embodiments, the transgenic plant has an improved agronomic or nutritional characteristic when cultivated in nitrogen-rich conditions as compared to a wild type plant cultivated in the same conditions. Also provided herein are commercial products (e.g., pu)p, paper, paper products, or lumber) derived from the transgenic plants (e.g., transgenic trees) produced using the methods provided herein.Type: ApplicationFiled: December 19, 2013Publication date: September 18, 2014Applicant: New York UniversityInventors: Gloria Coruzzi, Kenneth D. Birnbaum, Rodrigo A. Gutierrez, Miriam Gifford
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Patent number: 8624084Abstract: Provided herein are compositions and methods for producing transgenic plants. In specific embodiments, transgenic plants comprise a construct comprising a polynucleotide encoding microRNA167 (miR167), or precursor thereof, operably linked to a plant pericycle-specific promote, wherein the miR167 is ectopically overexpressed in the transgenic plants, and wherein the promoter is optionally a constitutive or inducible promoter. In some embodiments, the transgenic plant has an improved agronomic or nutritional characteristic when cultivated in nitrogen-rich conditions as compared to a wild type plant cultivated in the same conditions. Also provided herein are commercial products (e.g., pulp, paper, paper products, or lumber) derived from the transgenic plants (e.g., transgenic trees) produced using the methods provided herein.Type: GrantFiled: March 17, 2008Date of Patent: January 7, 2014Inventors: Gloria Coruzzi, Kenneth D. Birnbaum, Miriam Gifford, Rodrigo A. Gutierrez
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Publication number: 20120151635Abstract: Provided herein are compositions and methods for producing transgenic plants. In specific embodiments, transgenic plants comprise a construct comprising a polynucleotide encoding CCA1, GLK1 or bZIP1, operably linked to a plant-specific promote, wherein the CCA1, GLK1 or bZIP1 is ectopically overexpressed in the transgenic plants, and wherein the promoter is optionally a constitutive or inducible promoter. In other embodiments, transgenic plants in which express a lower level of CCA1, GLK1 or bZIP1 are provided. Also provided herein are commercial products (e.g., pulp, paper, paper products, or lumber) derived from the transgenic plants (e.g., transgenic trees) produced using the methods provided herein.Type: ApplicationFiled: February 10, 2012Publication date: June 14, 2012Inventors: Gloria Coruzzi, Rodrigo A. Gutierrez, Damion C. Nero
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Patent number: 8153863Abstract: Provided herein are compositions and methods for producing transgenic plants. In specific embodiments, transgenic plants comprise a construct comprising a polynucleotide encoding CCA1, GLK1 or bZIP1, operably linked to a plant-specific promote, wherein the CCA1, GLK1 or bZIP1 is ectopically overexpressed in the transgenic plants, and wherein the promoter is optionally a constitutive or inducible promoter. In other embodiments, transgenic plants in which express a lower level of CCA1, GLK1 or bZIP1 are provided. Also provided herein are commercial products (e.g., pulp, paper, paper products, or lumber) derived from the transgenic plants (e.g., transgenic trees) produced using the methods provided herein.Type: GrantFiled: March 24, 2008Date of Patent: April 10, 2012Assignee: New York UniversityInventors: Gloria Coruzzi, Rodrigo A. Gutierrez, Damion C. Nero
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Patent number: 8062996Abstract: The present invention relates to a family of GluR in plants, including ionotropic (iGluR), metabotropic (mGluR) and other glutamate-like plant receptors. The plant GluRs of the invention may function as signal transducers involved in the regulation of plant growth. The invention also relates to the identification of compounds that modulate the activity of the plant GluR, and the use of such compounds as plant growth regulators, including herbicides.Type: GrantFiled: August 16, 2002Date of Patent: November 22, 2011Assignee: New York UniversityInventors: Gloria Coruzzi, Igor Oliveira, Hon-Ming Lam, Ming-Hsiun Hsieh
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Publication number: 20110179519Abstract: Provided herein are compositions and methods for producing transgenic plants. In specific embodiments, transgenic plants comprise a construct comprising a polynucleotide encoding CCA1, GLK1 or bZIP1, operably linked to a plant-specific promote, wherein the CCA1, GLK1 or bZIP1 is ectopically overexpressed in the transgenic plants, and wherein the promoter is optionally a constitutive or inducible promoter. In other embodiments, transgenic plants in which express a lower level of CCA1, GLK1 or bZIP1 are provided. Also provided herein are commercial products (e.g., pulp, paper, paper products, or lumber) derived from the transgenic plants (e.g., transgenic trees) produced using the methods provided herein.Type: ApplicationFiled: March 9, 2011Publication date: July 21, 2011Inventors: Gloria Coruzzi, Rodrigo A. Gutierrez, Damion C. Nero
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Patent number: 7805703Abstract: The invention relates to a system and method for visually representing the interactions of input variables and output variables using a visualization field. The method comprises generating a visualization field on a display device, generating input variable indicators representative of the input variables, positioning the input variable indicators relative to the visualization field, generating interaction indicators, which are indicators of the input variables, positioning the interaction indicators relative to the visualization field, and adjusting the appearance of the interaction indicators to reflect the values of the output variables. The interaction indicators may also comprise association indicators that identify the input variables associated with the interaction indicators.Type: GrantFiled: December 16, 2005Date of Patent: September 28, 2010Assignee: New York UniversityInventors: Dennis Shasha, Rodrigo Gutierrez, W. Bradford Paley, Christopher Poultney, Gloria Coruzzi
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System and process of determining a biological pathway based on a treatment of a biological specimen
Patent number: 7739053Abstract: Provided herein is a system and method for analyzing microarray data (transcriptome profiles), metabolite data (metabolome profiles), protein level data (proteome profiles), or any combination thereof to determine the biochemical pathways affected by a treatment. The system and method can be used to generate biochemical pathway information for any organism for which metabolic profile data can be obtained. The system and method may allow users to query the pathways generated and to filter the results of queries based on the -omic profile data, pathways involving molecules of interest, notions of biochemical importance, milestone molecules, and other factors. The system and method may also be suitable for discovery of regulatory sequences in genes.Type: GrantFiled: January 14, 2005Date of Patent: June 15, 2010Assignee: New York UniversityInventors: Peter Palenchar, Dennis Shasha, Michael Chou, Marc Rejali, Yair Dorsett, Andrei Kouranov, Gloria Coruzzi -
Publication number: 20090094711Abstract: Provided herein are compositions and methods for producing transgenic plants. In specific embodiments, transgenic plants comprise a construct comprising a polynucleotide encoding microRNA167 (miR167), or precursor thereof, operably linked to a plant pericycle-specific promote, wherein the miR167 is ectopically overexpressed in the transgenic plants, and wherein the promoter is optionally a constitutive or inducible promoter. In some embodiments, the transgenic plant has an improved agronomic or nutritional characteristic when cultivated in nitrogen-rich conditions as compared to a wild type plant cultivated in the same conditions. Also provided herein are commercial products (e.g., pulp, paper, paper products, or lumber) derived from the transgenic plants (e.g., transgenic trees) produced using the methods provided herein.Type: ApplicationFiled: March 17, 2008Publication date: April 9, 2009Inventors: Gloria Coruzzi, Kenneth D. Birnbaum, Miriam Gifford, Rodrigo A. Gutierrez
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Publication number: 20090083876Abstract: Provided herein are compositions and methods for producing transgenic plants. In specific embodiments, transgenic plants comprise a construct comprising a polynucleotide encoding CCA1, GLK1 or bZIP1, operably linked to a plant-specific promote, wherein the CCA1, GLK1 or bZIP1 is ectopically overexpressed in the transgenic plants, and wherein the promoter is optionally a constitutive or inducible promoter. In other embodiments, transgenic plants in which express a lower level of CCA1, GLK1 or bZIP1 are provided. Also provided herein are commercial products (e.g., pulp, paper, paper products, or lumber) derived from the transgenic plants (e.g., transgenic trees) produced using the methods provided herein.Type: ApplicationFiled: March 24, 2008Publication date: March 26, 2009Inventors: Gloria Coruzzi, Rodrigo A. Gutierrez, Damion C. Nero
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Publication number: 20060286541Abstract: The invention relates to a system and method for visually representing the interactions of a plurality of input variables and at least one output variable, the method comprising the steps of generating a visualization field on a display device, generating on the display device at least one input variable indicator representative of at least one of the plurality of input variables, positioning each of the input variable indicators relative to the visualization field, generating on the display device at least one interaction indicator, the interaction indicator being an indicator of a combination of at least one input variable, positioning each of the interaction indicators relative to the visualization field, and adjusting the appearance of the interaction indicators on the display device to reflect at least one value of the output variables.Type: ApplicationFiled: December 16, 2005Publication date: December 21, 2006Inventors: Dennis Shasha, Rodrigo Gutierrez, W. Bradford Paley, Christopher Poultney, Gloria Coruzzi
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System and process of determining a biological pathway based on a treatment of a biological specimen
Publication number: 20050260615Abstract: Provided herein is a system and method for analyzing microarray data (transcriptome profiles), metabolite data (metabolome profiles), protein level data (proteome profiles), or any combination thereof to determine the biochemical pathways affected by a treatment. The system and method can be used to generate biochemical pathway information for any organism for which metabolic profile data can be obtained. The system and method may allow users to query the pathways generated and to filter the results of queries based on the -omic profile data, pathways involving molecules of interest, notions of biochemical importance, milestone molecules, and other factors. The system and method may also be suitable for discovery of regulatory sequences in genes.Type: ApplicationFiled: January 14, 2005Publication date: November 24, 2005Inventors: Peter Palenchar, Dennis Shasha, Michael Chou, Marc Rejali, Yair Dorsett, Andrei Kouranov, Gloria Coruzzi -
Publication number: 20030022305Abstract: The present invention relates to a family of GluR in plants, including ionotropic (iGluR), metabotropic (mGluR) and other glutamate-like plant receptors. The plant GluRs of the invention may function as signal transducers involved in the regulation of plant growth. The invention also relates to the identification of compounds that modulate the activity of the plant GluR, and the use of such compounds as plant growth regulators, including herbicides.Type: ApplicationFiled: August 16, 2002Publication date: January 30, 2003Applicant: New York University.Inventors: Gloria Coruzzi, Igor Oliveira, Hon-Ming Lam, Ming-Hsiun Hsieh