Abstract: A compound having the structures: or a pharmaceutically acceptable salt thereof, or a pharmaceutically acceptable solvate of said compound or pharmaceutically acceptable salt, wherein; R selected from the group consisting of H, C1-C6 alkyl, C1-C6 alkoxy and —(CH2)m—W, where W is C3-C8 cycloalkyl, bicycloalkyl, bridged bicycloalkyl, phenyl, 5- or 6-membered heteroaryl or heterocyclic containing one, two or three heteroatoms selected from the group consisting of N, S and O atoms; wherein each of said alkyl, cycloalkyl, alkoxy, heterocyclic, phenyl, naphthyl or heteroaryl may be unsubstituted or substituted by phenyl, halo, cyano, deuterium, hydroxy, C1-C6 alkyl, C1-C6 alkoxy, —SO2—R?, —CONR?R?, NR?COR?, —NR?CONR?R?, —NR?CO2R?, —(CH2)n—SO2—R?, —NHSO2—R?, —NR?SO2—R?, —SO2NR?R?, NR?R? or SR? where R? and R? are independently H, C1-C6 alkyl or C3-C8 cycloalkyl; R1 selected from the group consisting of phenyl, naphthyl, 5- or 6-membered heteroaryl or heterocyclic containing one, two, three or four heteroatoms se

Abstract: The invention relates to a nucleic acid sequence that improves resistance to biotrophic pathogens, in particular to Pseudomonas syringae, without affecting susceptibility to necrotrophs, in particular Botrytis cinerea. The present invention also relates to a plant that comprises the nucleic acid of the invention and a method to generate plants resistant to biotrophic pathogens and necrotrophs.

Abstract: A method for making a nanocatalyst includes the steps of forming a mixture of a catalyst precursor, and a crude oil media, wherein the catalyst precursor is insoluble in the oil media, then heating the mixture in the presence of a stability agent, thereby liberating the catalyst particles from the precursor while the stabilizing agent prevents growth of the catalyst particle so that nanocatalyst particles form and are maintained in the oil media. The resulting catalyst composition as well as a hydroconversion process using the catalyst are also disclosed.

Abstract: Film and sheet materials, and articles made therefrom, such as bags, pouches, trays, etc., comprise one or more layers of a thermoplastic, homogeneous alpha-olefin/vinyl aromatic copolymer, preferably an ethylene/styrene copolymer. The alpha-olefin/vinyl aromatic copolymer has properties which can can provide a desired performance characteristics such as impact resistance, printability, RF sealability, free shrink, optics, as well as many others. The homogeneous alpha-olefin/vinyl aromatic copolymer may be present in a monolayer film, either alone or in a blend, or may be included in one or more layers of a multilayer film. Also included is a multilayer thermoformable article comprising a web having a film of such alpha-olefin/vinyl aromatic copolymers therto. Finally, also included is an RF-sealable film comprising such copolymers.

Abstract: Film and sheet materials, and articles made therefrom, such as bags, pouches, trays, etc., comprise one or more layers of a thermoplastic, homogeneous alpha-olefin/vinyl aromatic copolymer, preferably an ethylene/styrene copolymer. The alpha-olefin/vinyl aromatic copolymer has properties which can can provide a desired performance characteristics such as impact resistance, printability, RF sealability, free shrink, optics, as well as many others. The homogeneous alpha-olefin-vinyl aromatic copolymer may be present in a mono-layer film, either alone or in a blend, or may be included in one or more layers of a multilayer film. Also included is a multilayer thermoformable article comprising a web having a film of such alpha-olefin/vinyl aromatic copolymers thereto. Finally, also included is an RF-sealable film comprising such copolymers.