Patents by Inventor Gloria Guohong ZHANG

Gloria Guohong ZHANG has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ANTI-PD-1/CD47 BISPECIFIC ANTIBODY AND USE THEREOF
    Publication number: 20240084012
    Abstract: An isolated bispecific antibody or antigen-binding portion thereof includes a first chain which specifically binds to human PD-1(hPD-1) and blocks the interaction between hPD-1 and PD-L1, and a second chain which specifically binds to human CD47 and inhibits its interaction with SIRP-alpha, where the first chain and the second chain are coupled in a knob-in-hole format through their respective CH3 domain.
    Type: Application
    Filed: December 31, 2021
    Publication date: March 14, 2024
    Inventors: Chun-Jen LIN, Cheng-Chi CHAO, Chang-Hsin Chen, Gloria Guohong ZHANG, Guochen YAN