Abstract: Tropomyosin-related kinase inhibitors (Trk inhibitors) are small molecule compounds useful in the treatment of disease. Trk inhibitors can be used as pharmaceutical agents and in pharmaceutical compositions. Trk inhibitors are useful in the treatment of inflammatory diseases, autoimmune disease, defects of bone metabolism and/or cancer, and are particularly useful in the treatment of osteoarthritis (OA), pain, and pain associated with OA. Trk inhibitors are also useful for inhibiting tropomyosin-related kinase A (TrkA), tropomyosin-related kinase B (TrkB), tropomyosin-related kinase C (TrkC), and/or c-FMS (the cellular receptor for colony stimulating factor-1 (CSF-1)).

Abstract: An example electronic device includes a display; a communication circuit; a memory storing one or instructions; and a processor for executing the one or more instructions to configure the processor to control the electronic device to: display, on the display, a message compose screen; receive message compose inputs to the message compose screen for composing a message; receive a message send input for sending the message via the communication circuit; set a timer; and send the message, via the communication circuit, after expiration of the timer.

Abstract: The following disclosure presents a wearable reusable shell, configured to hold an absorbent article, for use particularly in economically disadvantaged communities and/or communities with a water shortage. The wearable reusable shell comprises a base having a pair of wings extending from a center portion, an inner layer positioned along the center portion of the base, and an outer layer positioned along the center portion of the base and on top of the inner layer. Extending over the outer layer is at least one band configured to hold an disposable absorbent article in place. The present disclosure also presents a hybrid sanitary napkin (and a kit therefor) and methods of making and using a wearable reusable shell.

Abstract: A condiment package includes a front panel and a rear panel in facing relation to the front panel. Side seals are used to seal the front and rear panels to each other along sides thereof and top and bottom seals are used to seal the front and rear panels to each other a top of the package and at a bottom of the package. Indicia printed on the front or rear panel indicates, at a minimum, the contents of the package and advertising indicia on other of the front or rear panel represents a person or entity other than that represented by the contents indicia. An advertising medium is also disclosed.