Patents by Inventor Godefridus Franciscus Bernardus Hulshof

Godefridus Franciscus Bernardus Hulshof has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230380976
    Abstract: An object for altering cell behavior includes a surface part provided with at least one topography configured to modulate at least one of morphology, proliferation, biochemical functioning, differentiation, attachment, migration, signaling, or cell death of a cell population by physical stimulation, where the at least one topography includes a surface and multiple protrusions protruding from the surface, where the protrusions define multiple valleys between adjacent protrusions such that the adjacent protrusions do not touch, where each protrusion includes at least one protrusion element, where the top surface area of the at least one protrusion element has a complex shape comprising a combination of basic shapes, interconnected by one or more overlapping portions, the basic shapes including at least one of a circle, oval, triangle, square, rectangle, trapezoid, pentagon, hexagon, heptagon or octagon.
    Type: Application
    Filed: June 7, 2023
    Publication date: November 30, 2023
    Inventors: Jan de Boer, Berendien Jacoba Papenburg, Godefridus Franciscus Bernardus Hulshof
  • Patent number: 11744708
    Abstract: The invention pertains to surface topographies which can be used to modulate the morphology, proliferation, biochemical functioning, differentiation, attachment, migration, signaling, and/or cell death of a cell population by physical stimulation. Such topographies can be applied in vitro and in vivo to modulate cell behavior. Specific examples include implants provided with a topography of the invention which regulates the immune response, or an implant which increases osteogenesis. The invention furthermore pertains to objects which are used in vitro to modulate cell behavior.
    Type: Grant
    Filed: February 16, 2017
    Date of Patent: September 5, 2023
    Assignee: Koninklijke Philips N.V.
    Inventors: Jan de Boer, Berendien Jacoba Papenburg, Godefridus Franciscus Bernardus Hulshof