Abstract: An optical connector system for reversible optical connection between two optical fibers (102, 104) with their end parts inside respective ferrules. A receptacle arrangement has a receiving body (105) for receiving at least one of the ferrules (103). An optical element (106) of the receptacle arrangement serves to provide optical connection between the two optical fibers in a connected state of the optical connector system, and at the same time, the optical element (106) serves as a sterility barrier between the two optical fibers. The optical element (106) can be an optical waveguide, e.g. a piece of optical fiber similar to the two optical fibers (102, 104), and arranged within the receiving body (105). Alternatively, the optical element may be a thin flexible membrane (207, 307) which is optically transparent.

Abstract: A cartridge includes an inlet portion that is connected to an assay chamber and a suction reservoir. The inlet portion is configured to allow a direct uptake of sample medium. During this uptake, air is trapped in the assay chamber, which prevents a premature entrance of the sample medium into the assay chamber. The transfer of the sample medium from the inlet portion to the assay chamber is thus controllably initiated at a later time, for example by opening a vent port connected to the assay chamber.

Abstract: An optical connector system for reversible optical connection between two optical fibers (102, 104) with their end parts inside respective ferrules. A receptacle arrangement has a receiving body (105) for receiving at least one of the ferrules (103). An optical element (106) of the receptacle arrangement serves to provide optical connection between the two optical fibers in a connected state of the optical connector system, and at the same time, the optical element (106) serves as a sterility barrier between the two optical fibers. The optical element (106) can be an optical waveguide, e.g. a piece of optical fiber similar to the two optical fibers (102, 104), and arranged within the receiving body (105). Alternatively, the optical element may be a thin flexible membrane (207, 307) which is optically transparent.

Abstract: An optical connector system for reversible optical connection between two optical fibers (102, 104) with their end parts inside respective ferrules. A receptacle arrangement has a receiving body (105) for receiving at least one of the ferrules (103). An optical element (106) of the receptacle arrangement serves to provide optical connection between the two optical fibers in a connected state of the optical connector system, and at the same time, the optical element (106) serves as a sterility barrier between the two optical fibers. The optical element (106) can be an optical waveguide, e.g. a piece of optical fiber similar to the two optical fibers (102, 104), and arranged within the receiving body (105). Alternatively, the optical element may be a thin flexible membrane (207, 307) which is optically transparent.

Abstract: The invention relates to a cartridge (10) for processing of a liquid sample, for example for the detection of components in a sample of blood. The cartridge comprises a fluidic system with an intake port (12) leading via an intake capillary channel (13) to a storage chamber (14). Moreover, a feeding capillary channel (15) leads from the storage chamber (14) to a detection chamber (16). The design of the cartridge (10) is such that the intake capillary channel (13) that connects the intake port (12) to the storage chamber (14), has a capillary suction pressure sufficiently high to drive some sample from the intake port to the storage chamber without need of any additional pressure. Furthermore the cartridge a flow control element (18, 20) adapted to be externally controllable such that the sample can be drawn from the storage chamber (14) towards the processing chamber (16) without any active pumping.

Abstract: The invention provides a process for the production of a (particulate) luminescent material comprising particles, especially substantially spherical particles, having a porous inorganic material core with pores, especially macro pores, which are at least partly filled with a polymeric material with luminescent quantum dots embedded therein, wherein the process comprises (i) impregnating the particles of a particulate porous inorganic material with pores with a first liquid (“ink”) comprising the luminescent quantum dots and a curable or polymerizable precursor of the polymeric material, to provide pores that are at least partly filled with said luminescent quantum dots and curable or polymerizable precursor; and (ii) curing or polymerizing the curable or polymerizable precursor within pores of the porous material, as well as a product obtainable thereby.

Abstract: The invention provides a process for the production of a (particulate) luminescent material comprising particles, especially substantially spherical particles, having a porous inorganic material core with pores, especially macro pores, which are at least partly filled with a polymeric material with luminescent quantum dots embedded therein, wherein the process comprises (i) impregnating the particles of a particulate porous inorganic material with pores with a first liquid (“ink”) comprising the luminescent quantum dots and a curable or polymerizable precursor of the polymeric material, to provide pores that are at least partly filled with said luminescent quantum dots and curable or polymerizable precursor; and (ii) curing or polymerizing the curable or polymerizable precursor within pores of the porous material, as well as a product obtainable thereby.

Abstract: An embodiment of the invention relates to a fluidic system (200) in which a first channel (210) and a second channel (230) are separated by a fluidic stop (220), for example a region with a hydrophobic coating and/or a structure (220) with non-capillary internal dimensions. Moreover, it comprises a flexible element (240) that is deformable to enable a flow of a medium across the fluidic stop.

Abstract: A luminescent product 100, a lamp and a light source are provided for converting light of a first color into light of a second color. The luminescent product 100 comprises a matrix polymer 108 and another material 106. The matrix polymer 108 comprises a luminescent material which converts light of a first color into light of a second color. The another material 106 is light transmitting. The luminescent product 100 is at least partially light transmitting and the matrix polymer has a three dimensional structure which has multiple surfaces being an interface between the matrix polymer and the another material to allow, in use, a light beam 104, which impinges on a side 102 of the luminescent product 100, to pass at least four times an interface between the matrix polymer 108 and the another material 106 before at least a part of the light beam 104 leaves the luminescent product 100 at another side 110 of the luminescent product 100.

Abstract: The invention relates to a cartridge (10) for processing of a liquid sample, for example for the detection of components in a sample of blood. The cartridge comprises a fluidic system with an intake port (12) leading via an intake capillary channel (13) to a storage chamber (14). Moreover, a feeding capillary channel (15) leads from the storage chamber (14) to a detection chamber (16). The design of the cartridge (10) is such that the intake capillary channel (13) that connects the intake port (12) to the storage chamber (14), has a capillary suction pressure sufficiently high to drive some sample from the intake port to the storage chamber without need of any additional pressure. Furthermore the cartridge a flow control element (18, 20) adapted to be externally controllable such that the sample can be drawn from the storage chamber (14) towards the processing chamber (16) without any active pumping.

Abstract: An optical connector system for reversible optical connection between two optical fibers (102, 104) with their end parts inside respective ferrules. A receptacle arrangement has a receiving body (105) for receiving at least one of the ferrules (103). An optical element (106) of the receptacle arrangement serves to provide optical connection between the two optical fibers in a connected state of the optical connector system, and at the same time, the optical element (106) serves as a sterility barrier between the two optical fibers. The optical element (106) can be an optical waveguide, e.g. a piece of optical fiber similar to the two optical fibers (102, 104), and arranged within the receiving body (105). Alternatively, the optical element may be a thin flexible membrane (207, 307) which is optically transparent.

Abstract: The invention provides a process for the production of a (particulate) luminescent material comprising particles, especially substantially spherical particles, having a porous inorganic material core with pores, especially macro pores, which are at least partly filled with a polymeric material with luminescent quantum dots embedded therein, wherein the process comprises (i) impregnating the particles of a particulate porous inorganic material with pores with a first liquid (“ink”) comprising the luminescent quantum dots and a curable or polymerizable precursor of the polymeric material, to provide pores that are at least partly filled with said luminescent quantum dots and curable or polymerizable precursor; and (ii) curing or polymerizing the curable or polymerizable precursor within pores of the porous material, as well as a product obtainable thereby.

Abstract: The invention relates to a cartridge (100) with an inlet portion (110) that is connected to an assay chamber (120) and a suction reservoir (140). The inlet portion (110) is designed for a direct uptake of sample medium, for example of blood from a patient. During this uptake, air is trapped in the assay chamber (120), which prevents a premature entrance of the medium into the assay chamber (120). The transfer of the medium to the assay chamber (120) can thus controllably be initiated at a later time, for example by opening a vent port (121) connected to the assay chamber (120).

Abstract: An embodiment of the invention relates to a fluidic system (200) in which a first channel (210) and a second channel (230) are separated by a fluidic stop (220), for example a region with a hydrophobic coating and/or a structure (220) with non-capillary internal dimensions. Moreover, it comprises a flexible element (240) that is deformable to enable a flow of a medium across the fluidic stop.

Abstract: A sensor device for sensing particles of a sample, the sensor device including a sensing unit adapted for sensing a detection signal indicative of the presence of the particles, a viscosity measurement unit adapted for measuring the viscosity of the sample, and a correction unit adapted for correcting the detection signal based on the measured viscosity.

Abstract: A luminescent product 100, a lamp and a light source are provided for converting light of a first color into light of a second color. The luminescent product 100 comprises a matrix polymer 108 and another material 106. The matrix polymer 108 comprises a luminescent material which converts light of a first color into light of a second color. The another material 106 is light transmitting. The luminescent product 100 is at least partially light transmitting and the matrix polymer has a three dimensional structure which has multiple surfaces being an interface between the matrix polymer and the another material to allow, in use, a light beam 104, which impinges on a side 102 of the luminescent product 100, to pass at least four times an interface between the matrix polymer 108 and the another material 106 before at least a part of the light beam 104 leaves the luminescent product 100 at another side 110 of the luminescent product 100.

Abstract: The invention relates to microfluidic systems, and more specifically to a microfluidic system comprising a capillary channel (14) and an inlet (12) for receiving a fluid, as well as a method of filling a capillary channel (14). Provided is a microfluidic system, having an inlet (12) for receiving a fluid, a capillary channel (14), an outlet (20) for letting excess fluid out, and a reservoir (10) for interfacing the inlet (12) to the capillary channel (14). The reservoir (10) forms a first passage from the inlet (12) to the outlet (20), and a second passage from the inlet (12) to an entrance (22) of the capillary channel (14). A hydraulic resistance of the first passage is sufficiently low in order to effect a pressure reduction at the entrance (22) of the capillary channel (14) when a fluid is received under pressure at the inlet (12).

Abstract: A microfluidic reactor arrangement (100) for use in detecting an analyte in a fluid sample (106) is described. The reactor arrangement is provided with a reagent providing means such that the reagent can be introduced after assembly of the reactor arrangement. The latter can be performed by introducing the reagent in the form of a solution or a dispersion and fixing it on a holding means (118) by removal of the liquid, i.e. by drying, the holding means comprising the reagent in a solid version in the detector chamber. Prior to the introduction of the reagent, components of the reactor arrangement already present, such as the sample inlet can be hydrophilised by a wetting hydrophilising technique. The invention relates to a manufacturing technique as well as to the resulting product. The invention furthermore relates to functionalizing of the reactor arrangement with a particular reagent for particular applications.

Abstract: A sensor device (50) for sensing particles (15) of a sample, the sensor device (50) comprising a sensing unit (11, 20) adapted for sensing a detection signal indicative of the presence of the particles (15), a viscosity measurement unit (11, 17, 20) adapted for measuring the viscosity of the sample, and a correction unit (20, 30) adapted for correcting the detection signal based on the measured viscosity.

Abstract: A LED is covered with an electroconductive layer, and a luminescent layer is deposited on the electroconductive layer by electrophoresis. The conductivity of the electroconductive layer is chosen to be such that the layer can be used as one of the electrodes during the electrophoresis, while the LED is not short-circuited by the electroconductive layer during normal operation.