Patents by Inventor Godfrey Jonah RAINEY

Godfrey Jonah RAINEY has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Neutralizing anti-influenza binding molecules and uses thereof
    Patent number: 11926657
    Abstract: Binding molecules, including bispecific antibodies that include at least two anti-influenza binding domains are disclosed, including binding molecules having a first binding domain that specifically binds influenza A virus and a second binding domain that specifically binds influenza B virus.
    Type: Grant
    Filed: November 11, 2022
    Date of Patent: March 12, 2024
    Assignee: MEDIMMUNE, LLC
    Inventors: Nicole Kallewaard-Lelay, Qing Zhu, Godfrey Jonah Rainey, Cuihua Gao, Srinath Kasturirangan, Changshou Gao
  • Bispecific binding molecules that target the tumor microenvironment and an immune checkpoint protein
    Patent number: 11718673
    Abstract: Bispecific binding proteins that bind IL-1? or IL-1R and a checkpoint protein are provided, together with methods of making the proteins. The checkpoint protein may be PD-1 or PD-L1. The binding proteins may have immunoglobulin-like structures that contain human Fab or scFv domains. A novel bispecific antibody format is provided. Methods of making the binding proteins are provided, together with pharmaceutical compositions containing the proteins. The binding proteins and pharmaceutical compositions may be used for treating or preventing diseases such as cancer.
    Type: Grant
    Filed: March 31, 2020
    Date of Patent: August 8, 2023
    Assignee: Immetas Therapeutics, Inc.
    Inventors: Jin Wang, Godfrey Jonah Rainey
  • NEUTRALIZING ANTI-INFLUENZA BINDING MOLECULES AND USES THEREOF
    Publication number: 20230112916
    Abstract: Binding molecules, including bispecific antibodies that include at least two anti-influenza binding domains are disclosed, including binding molecules having a first binding domain that specifically binds influenza A virus and a second binding domain that specifically binds influenza B virus.
    Type: Application
    Filed: November 11, 2022
    Publication date: April 13, 2023
    Inventors: Nicole KALLEWAARD-LELAY, Qing ZHU, Godfrey Jonah RAINEY, Cuihua GAO, Srinath KASTURIRANGAN, Changshou GAO
  • Neutralizing anti-influenza binding molecules and uses thereof
    Patent number: 11524993
    Abstract: Binding molecules, including bispecific antibodies that include at least two anti-influenza binding domains are disclosed, including binding molecules having a first binding domain that specifically binds influenza A virus and a second binding domain that specifically binds influenza B virus.
    Type: Grant
    Filed: December 1, 2020
    Date of Patent: December 13, 2022
    Inventors: Nicole Kallewaard-Lelay, Qing Zhu, Godfrey Jonah Rainey, Cuihua Gao, Srinath Kasturirangan, Changshou Gao
  • NEUTRALIZING ANTI-INFLUENZA BINDING MOLECULES AND USES THEREOF
    Publication number: 20210079069
    Abstract: Binding molecules, including bispecific antibodies that include at least two anti-influenza binding domains are disclosed, including binding molecules having a first binding domain that specifically binds influenza A virus and a second binding domain that specifically binds influenza B virus.
    Type: Application
    Filed: December 1, 2020
    Publication date: March 18, 2021
    Inventors: Nicole KALLEWAARD-LELAY, Qing ZHU, Godfrey Jonah RAINEY, Cuihua GAO, Srinath KASTURIRANGAN, Changshou GAO
  • Neutralizing anti-influenza binding molecules and uses thereof
    Patent number: 10882897
    Abstract: Binding molecules, including bispecific antibodies that include at least two anti-influenza binding domains are disclosed, including binding molecules having a first binding domain that specifically binds influenza A virus and a second binding domain that specifically binds influenza B virus.
    Type: Grant
    Filed: September 4, 2019
    Date of Patent: January 5, 2021
    Assignee: MEDIMMUNE, LLC
    Inventors: Nicole Kallewaard-Lelay, Qing Zhu, Godfrey Jonah Rainey, Cuihua Gao, Srinath Kasturirangan, Changshou Gao
  • Bispecific Binding Molecules That Target the Tumor Microenvironment and an Immune Checkpoint Protein
    Publication number: 20200308285
    Abstract: Bispecific binding proteins that bind IL-1? or IL-1R and a checkpoint protein are provided, together with methods of making the proteins. The checkpoint protein may be PD-1 or PD-L1. The binding proteins may have immunoglobulin-like structures that contain human Fab or scFv domains. A novel bispecific antibody format is provided. Methods of making the binding proteins are provided, together with pharmaceutical compositions containing the proteins. The binding proteins and pharmaceutical compositions may be used for treating or preventing diseases such as cancer.
    Type: Application
    Filed: March 31, 2020
    Publication date: October 1, 2020
    Inventors: Jin WANG, Godfrey Jonah RAINEY
  • NEUTRALIZING ANTI-INFLUENZA BINDING MOLECULES AND USES THEREOF
    Publication number: 20200109187
    Abstract: Binding molecules, including bispecific antibodies that include at least two anti-influenza binding domains are disclosed, including binding molecules having a first binding domain that specifically binds influenza A virus and a second binding domain that specifically binds influenza B virus.
    Type: Application
    Filed: September 4, 2019
    Publication date: April 9, 2020
    Inventors: Nicole KALLEWAARD-LELAY, Qing ZHU, Godfrey Jonah RAINEY, Cuihua GAO, Srinath KASTURIRANGAN, Changshou GAO
  • Neutralizing anti-influenza binding molecules and uses thereof
    Patent number: 10442854
    Abstract: Binding molecules, including bispecific antibodies that include at least two anti-influenza binding domains are disclosed, including binding molecules having a first binding domain that specifically binds influenza A virus and a second binding domain that specifically binds influenza B virus.
    Type: Grant
    Filed: May 31, 2016
    Date of Patent: October 15, 2019
    Assignee: MEDIMMUNE, LLC
    Inventors: Nicole Kallewaard-Lelay, Qing Zhu, Godfrey Jonah Rainey, Cuihua Gao, Srinath Kasturirangan, Changshou Gao
  • BISPECIFIC FUSION POLYPEPTIDES AND METHODS OF USE THEREOF
    Publication number: 20190241659
    Abstract: Provided herein are bispecific fusion proteins and methods of using the bispecific fusion proteins for treating cancer.
    Type: Application
    Filed: November 8, 2018
    Publication date: August 8, 2019
    Inventors: JOHN MUMM, YUE WANG, RYAN GILBRETH, RONALD HERBST, SCOTT HAMMOND, MICHAEL OBERST, GODFREY JONAH RAINEY, SIMON DOVEDI, JONATHAN SEAMAN, MICHELLE TURNHAM
  • NEUTRALIZING ANTI-INFLUENZA BINDING MOLECULES AND USES THEREOF
    Publication number: 20180155413
    Abstract: Binding molecules, including bispecific antibodies that include at least two anti-influenza binding domains are disclosed, including binding molecules having a first binding domain that specifically binds influenza A virus and a second binding domain that specifically binds influenza B virus.
    Type: Application
    Filed: May 31, 2016
    Publication date: June 7, 2018
    Inventors: Nicole KALLEWAARD-LELAY, Qing ZHU, Godfrey Jonah RAINEY, Cuihua GAO, Srinath KASTURIRANGAN, Changshou GAO