Patents by Inventor Goerge D. Cimino

Goerge D. Cimino has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Activation compounds and methods of synthesis of activation compounds
    Patent number: 5139940
    Abstract: The invention is directed to isopsoralen compound compositions that contain a variety of substitutions which yet permit their binding to nucleic acid polymers. Reaction conditions that activate these bound isopsoralens results in covalent crosslinking to the nucleic acid polymers. The resultant complex is inhibited from being a template for the template-directed enzymatic synthesis of a complementary nucleic acid polymer. Beside the isopsoralens compositions, the invention includes their synthesis, the nucleic acid complex production and detection, and the above inhibitory method of use of the isopsoralens.
    Type: Grant
    Filed: October 26, 1989
    Date of Patent: August 18, 1992
    Inventors: Stephen T. Isaacs, Goerge D. Cimino, Kenneth C. Metchette, John W. Tessman