Patents by Inventor Goffe Sytse ELSINGA

Goffe Sytse ELSINGA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9944694
    Abstract: The invention relates to the field of immunology and vaccine development. In particular, it relates to antibodies and fragments thereof against Staphylococcus aureus and to therapeutic and diagnostic uses thereof. Provided is an isolated antibody or a functional fragment thereof, which binds to an epitope of the Immunodominant Staphylococcal antigen A (IsaA), wherein said antibody comprises at least four Isa A epitope-binding CDR sequences selected from the group consisting of SEQ ID NO: 1; SEQ ID NO: 2; SEQ ID NO: 3; SEQ ID NO: 4; SEQ ID NO: 5; SEQ ID NO: 6, and functional equivalents thereof having an amino acid sequence that is at least 85% identical to an amino acid sequence of SEQ ID NO: 1-6.
    Type: Grant
    Filed: December 12, 2014
    Date of Patent: April 17, 2018
    Assignees: Rijksuniversiteit Groningen, Academisch Ziekenhuis Groningen
    Inventors: Jan Maarten Van Dijl, Girbe Buist, Hendrik Petrus Jozef Bonarius, Neeltje Margaretha Kooi, Goffe Sytse Elsinga, Herman Groen
  • Publication number: 20170002063
    Abstract: The invention relates to the field of immunology and vaccine development. In particular, it relates to antibodies and fragments thereof against Staphylococcus aureus and to therapeutic and diagnostic uses thereof. Provided is an isolated antibody or a functional fragment thereof, which binds to an epitope of the Immunodominant Staphylococcal antigen A (IsaA), wherein said antibody comprises at least four Isa A epitope-binding CDR sequences selected from the group consisting of SEQ ID NO: 1; SEQ ID NO: 2; SEQ ID NO: 3; SEQ ID NO: 4; SEQ ID NO: 5; SEQ ID NO: 6, and functional equivalents thereof having an amino acid sequence that is at least 85% identical to an amino acid sequence of SEQ ID NO: 1-6.
    Type: Application
    Filed: December 12, 2014
    Publication date: January 5, 2017
    Inventors: Jan Maarten VAN DIJL, Girbe BUIST, Hendrik Petrus Jozef BONARIUS, Neeltje Margaretha KOOI, Goffe Sytse ELSINGA, Herman GROEN