Abstract: Various methods for automatically generating a structured clinical report by using a pre-defined template structure and mapping it to the imaging data set of an organ (such as a CT or MR scan) are presented. A template or knowledge structure may describe the general structure of a tube-like organ, and may be based on prior knowledge related to acceptable ranges of measurement or rations for a particular organ or area of interest. The organ of interest may be segmented out from original image slices. In exemplary embodiments of the present invention a corresponding centerline can be calculated and a skeleton of the tube-like organ can be created. Based on the centerline extracted, a knowledge structure (template) can be mapped to the organ data. Since required measurements may be defined in the template, actual measurements can be automatically calculated for the structure.