Patents by Inventor Gokul M. Das

Gokul M. Das has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • EXPLOITING ESTROGEN RECEPTOR BETA AND TP53 INTERACTION AS A NEW THERAPEUTIC STRATEGY FOR CANCER
    Publication number: 20220125744
    Abstract: To induce cancer cell death, cancer cells are selected that express estrogen-receptor ? (ER?) and mutant tumor protein 53 (TP53). An agent that increases ER? protein expression is administered to the cells to induce cell death. To treat a subject having a cancer that is characterized by cancer cells expressing ER? and mutant TP53, an agent that increases ER? protein expression is administered to induce cell death in the cancer cells. To increase estrogen receptor ? (ER?) expression levels in a subject having low ER? expression levels, tamoxifen is administered to increase ER? protein levels in the subject. To treat a subject having cancer cells expressing estrogen-receptor ? (ER?) and wildtype tumor protein 53 (TP53), an agent that inhibits ER? and TP53 binding interaction is administered to induce cell death in the cancer cells of the subject.
    Type: Application
    Filed: November 7, 2019
    Publication date: April 28, 2022
    Applicant: Health Research, Inc.
    Inventor: Gokul M. Das