Patents by Inventor Golfo Skokotas

Golfo Skokotas has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Propargylic and allenic sulfones
    Patent number: 5237101
    Abstract: Propargylic and allenic sulfones are disclosed having the ability to selectively cleave nucleic acids, especially deoxyribonucleic acid. Such compositions are capable of being synthetically modified to effect cleavage at selected, sequenced sites on nucleic acids.
    Type: Grant
    Filed: January 26, 1990
    Date of Patent: August 17, 1993
    Assignee: The Trustees of the Univ. of Penna.
    Inventors: K. C. Nicolaou, Guido Zaccarello, Golfo Skokotas, Peter Maligres
  • Golfomycin derivatives: fused ring cyclodecadiyne derivatives having DNA-cleaving properties and antitumor activity
    Patent number: 5136099
    Abstract: 5-Hydroxy-benzo-(1',2')-cyclodeca-2,7-diyne-1-one and derivatives thereof and related fused ring diyneone macrocyclic compounds are disclosed. The compounds possess DNA-cleaving, antibiotic and tumor growth-inhibiting properties. Methods of making and using the same are also disclosed.
    Type: Grant
    Filed: August 1, 1990
    Date of Patent: August 4, 1992
    Assignee: Scripps Clinic and Research Foundation
    Inventors: Golfo Skokotas, Kyriacos C. Nicolaou