Abstract: A computing device system and method for detecting cell death in a biological sample is provided. A plurality of optical coherence tomography (OCT) data sets are received, each representative of OCT backscatter data collected from the biological sample and comprising respective signal fluctuation as a function of time at different respective times over a given time period. Respective indications of respective signal decorrelation rates are determined for each of the plurality of OCT data sets at each of the different respective time.