Abstract: The present invention relates to the field of biomedicine, particularly to double-stranded RNA molecules targeting CKIP-1 and uses thereof, particularly to use of the double-stranded RNA molecules for the treatment of inflammatory diseases such as arthritis, particularly rheumatoid arthritis.

Abstract: A P2X3 and/or P2X2/3 receptor antagonist of formula (I), a pharmaceutical composition comprising the same, and a use thereof in preparing a drug for preventing or treating a disease mediated by the P2X3 and/or P2X2/3 receptor antagonist.

Abstract: The present invention discloses a receptor inhibitor of formula (I), a composition comprising the same and the usage thereof.

Abstract: A method for estimating resistivity and dielectric constant values of a multi-layer subterranean formation acquiring electromagnetic propagation measurements of the subterranean formation and processing the measurements via inversion to compute the resistivity and dielectric constant values. A one-dimensional formation model is utilized including a plurality of formation layers in which each of the formation layers includes a resistivity value and a dielectric constant value.

Abstract: A network learning system includes a host being coupled to a first user end and a second user end. A processor of the host end is configured to perform the following steps of: storing original lesson information being sent from the first user end in which the original lesson information has a plurality of content sections; selecting the content sections to form adaptive lesson information based on a learning condition of the second user end; sending the adaptive lesson information to the second user end so that an output device of the second user end outputs the adaptive lesson information based on a view of a simulated space; when the output device of the second user end outputs the adaptive lesson information, recording a value from an input device of the second user end.

Abstract: Properties of a geological formation, such as dielectric constant and conductivity, may be determined by a propagation well log data acquired by a propagation well logging tool based at least in part on a relative longitudinal position of two or more receivers of the propagation well logging tool. In some embodiments, the relative longitudinal position of the at least two receivers is based at least in part on a first distance between a first receiver of the at least two receivers and a transmitter of the propagation well logging tool and a second distance between a second receiver of the at least two receivers and the transmitter.

Abstract: The present invention relates to a Rho-associated protein kinase inhibitor of formula (I), a pharmaceutical composition comprising the same, a preparation method thereof, and a use of the same in preventing or treating a disease mediated by Rho-associated protein kinase (ROCK).

Abstract: A P2X3 and/or P2X2/3 receptor antagonist of formula (I), a pharmaceutical composition comprising the same, and a use thereof in preparing a drug for preventing or treating a disease mediated by the P2X3 and/or P2X2/3 receptor antagonist.

Abstract: A P2X3 and/or P2X2/3 receptor antagonist of formula (I), a pharmaceutical composition comprising the same, and a use thereof in preparing a drag for preventing or treating a disease mediated by the P2X3 and/or P2X2/3 receptor antagonist.

Abstract: The present disclosure relates to a data analysis method and a data analysis system thereof. The data analysis method includes steps of: receiving a first learning content data, and adding multiple first segmentation marks to the first learning content data to divide multiple first learning sections on the first learning content data. The first learning sections are arranged according to a time axis. Searching a first keyword string corresponding to each first learning section from the first learning sections. Receiving a analysis command, and analyzing the analysis command with the first keyword string of each of the first learning content data to obtain multiple first similarities, corresponding to the analysis command and each of the first learning sections. Finally, searching for the first learning section with the highest similarity.

Abstract: The present invention relates to a Rho-associated protein kinase inhibitor of formula (I), a pharmaceutical composition comprising the same, a preparation method thereof, and a use of the same in preventing or treating a disease mediated by Rho-associated protein kinase (ROCK).

Abstract: Methods and systems are provided that use resistivity log data to estimate water saturation of formation rock and/or other useful formation parameters (such as CEC) in a manner that accounts for one or more electrically conductive mineral components contained in the formation rock.

Abstract: The present invention relates to the field of biomedicine, particularly to double-stranded RNA molecules targeting CKIP-1 and uses thereof, particularly to use of the double-stranded RNA molecules for the treatment of inflammatory diseases such as arthritis, particularly rheumatoid arthritis.

Abstract: A Rho-associated protein kinase (ROCK) inhibitor represented by formula (I), a pharmaceutical composition comprising same, and a use thereof for preventing or treating ROCK-mediated diseases.

Abstract: The present invention discloses a receptor inhibitor of formula (I), a composition comprising the same and the usage thereof.

Abstract: Properties of a geological formation, such as vertical resistivity values, horizontal resistivity values, dip, and azimuth may be determined by inverting electromagnetic (EM) well log data based at least in part on an anisotropic formation model and a cost function. The cost function may include a data misfit term, a smoothness term, and an entropy term. In some embodiments, one or more of the data misfit term, the smoothness term, and the entropy term may be represented as functions of vertical conductivity and horizontal conductivity. The cost function may include one or more regularization parameters that are based at least in part on the data misfit term. Further, the cost function may include one or more relaxation factors that are based at least in part on a ratio of the Hessians of the smoothness term and the data misfit term.

Abstract: The present invention relates to the field of biomedicine, particularly to double-stranded RNA molecules targeting CKIP-1 and uses thereof, particularly to use of the double-stranded RNA molecules for the treatment of inflammatory diseases such as arthritis, particularly rheumatoid arthritis.

Abstract: The highly valuable properties of resistivity and dielectric constant of a geological formation may be determined using an induction measurement, even for a geological formation with bed boundary or dipping effects, using a one-dimensional (1D) formation model. Induction measurements may be obtained in a wellbore through the geological formation using one or more downhole tools. One or more processors may be used to perform an inversion to estimate resistivity and dielectric constant values of the geological formation. The inversion may be performed using the induction measurements and a one-dimensional model that includes a number of geological layers.

Abstract: The present invention relates to a Rho-associated protein kinase inhibitor of formula (I), a pharmaceutical composition comprising the same, a preparation method thereof, and a use of the same in preventing or treating a disease mediated by Rho-associated protein kinase (ROCK).

Abstract: A formation characterization system can include a processor; memory accessibly by the processor; instructions stored in the memory and executable by the processor to instruct the system to: acquire induction measurements in a borehole in a formation using an induction tool; determine dielectric properties of the formation using the induction measurements; and generate a log that characterizes particles in the formation based on the dielectric properties.