Abstract: Kits for a drug delivery device or system include a housing having compartments, components to be secured within the compartments, and an instruction manual providing a series of steps. In some kits, a page of the instruction manual providing a step associated with a component does not overlay the compartment in which the associated component is to be secured, whereas all preceding pages do overlay the compartment, such that the step and the associated component are first displayed together. In some kits, a color is displayed with a compartment and with a step associated with the component to be secured in the compartment. In some kits, the housing includes two chambers, each chamber having the compartments in which components associated with a first subset of steps and a second subset of steps, respectively are secured.

Abstract: Transfer devices with vial adapter and/or an infusion set for reducing overdosing/underdosing of an infusion bag are provided. The transfer device provides user-controlled fluid transferring between an infusion liquid container and a drug-containing container. In one aspect, the transfer device provides user-controlled venting that can be used during liquid transfer between the infusion liquid container and a drug-containing container.

Abstract: Examples relate to fluid collection devices, and related systems and methods. In some embodiments, a fluid collection device includes a fluid impermeable barrier and an elongated body that is at least partially fluid permeable. The fluid impermeable barrier has a distal end region and a proximal end region defining an aperture sized and dimensioned to have urine drawn therethrough by a vacuum source. The elongated body has a portion of the body that is free from being covered by the fluid impermeable barrier between the distal end region and the proximal end region and positioned on the fluid collection device to receive urine discharged from a urethra at least proximate to the portion of the body. The fluid collection device includes at least one of the fluid impermeable barrier being an injection molded fluid impermeable barrier or the body includes at least an extruded support.

Abstract: Examples relate to fluid collection devices, and related systems and methods. In some embodiments, a fluid collection device includes an elongated fluid impermeable barrier and an elongated body. The fluid collection device includes at least one of the fluid impermeable barrier being an injection molded fluid impermeable barrier, the body including at least an extruded support, the fluid impermeable barrier including one or more regions of film welded together, the fluid impermeable barrier including a die cut foam fluid impermeable barrier, or the fluid impermeable barrier including a plastic tube welded at the proximal end region and the distal end region.

Abstract: Microfluidic devices for cell sorting or cell fractionation are disclosed. A microfluidic device can comprise one or more inlets, a first wall and a second wall, and two or more outlets. The first and second walls can be substantially planar to each other and the first wall having can have a plurality of ridges protruding from the first wall and defining a compression gap between the ridge and a surface of the second wall. The microfluidic device can also be a cell sorting device for sorting a plurality of cells based on one or more biophysical cellular properties including size, elasticity, viscosity, and/or viscoelasticity wherein the cells are subjected to one or more compressions due to the compression gap. Also disclosed are methods for cell sorting based on a variety of biophysical cellular properties.

Abstract: A system configured to create a self-contained negative pressure environment (SCONE) to remove airborne particulates emitted from a patient. The system prevents exposure to pathogenic biological airborne particulates during triage, transportation, and treatment, including aerosol generating procedures (AGPs) and end of life care. This system is directed to a collapsible device having a flexible cover covering two support members, with openings in the flexible cover such that medical professionals can reach in and operate within. The present invention is further adaptable to patients and operating environments of various sizes.

Abstract: Transfer devices with vial adapter and/or an infusion set for reducing overdosing/underdosing of an infusion bag are provided. The transfer device provides user- controlled fluid transferring between an infusion liquid container and a drug-containing container. In one aspect, the transfer device provides user-controlled venting that can be used during liquid transfer between the infusion liquid container and a drug-containing container.

Abstract: A system configured to create a self-contained negative pressure environment (SCONE) to remove airborne particulates emitted from a patient. The system prevents exposure to pathogenic biological airborne particulates during triage, transportation, and treatment, including aerosol generating procedures (AGPs) and end of life care. This system is directed to a collapsible device having a flexible cover covering two support members, with openings in the flexible cover such that medical professionals can reach in and operate within. The present invention is further adaptable to patients and operating environments of various sizes.

Abstract: A system directed to providing a self-contained negative pressure environment (SCONE) to remove airborne particulates emitted from a patient. The system prevents exposure to pathogenic biological airborne particulates during triage, transportation, and treatment, including aerosol generating procedures (AGPs) and end of life care. This system is directed to a collapsible device having a flexible cover covering two support members, with openings in the flexible cover such that medical professionals can reach in and operate within. The present invention is further adaptable to patients and operating environments of various sizes.

Abstract: Microfluidic devices for cell sorting or cell fractionation are disclosed. A microfluidic device can comprise one or more inlets, a first wall and a second wall, and two or more outlets. The first and second walls can be substantially planar to each other and the first wall having can have a plurality of ridges protruding from the first wall and defining a compression gap between the ridge and a surface of the second wall. The microfluidic device can also be a cell sorting device for sorting a plurality of cells based on one or more biophysical cellular properties including size, elasticity, viscosity, and/or viscoelasticity wherein the cells are subjected to one or more compressions due to the compression gap. Also disclosed are methods for cell sorting based on a variety of biophysical cellular properties.

Abstract: Microfluidic devices for cell sorting or cell fractionation are disclosed. A microfluidic device can comprise one or more inlets, a first wall and a second wall, and two or more outlets. The first and second walls can be substantially planar to each other and the first wall having can have a plurality of ridges protruding from the first wall and defining a compression gap between the ridge and a surface of the second wall. The microfluidic device can also be a cell sorting device for sorting a plurality of cells based on one or more biophysical cellular properties including size, elasticity, viscosity, and/or viscoelasticity wherein the cells are subjected to one or more compressions due to the compression gap. Also disclosed are methods for cell sorting based on a variety of biophysical cellular properties.

Abstract: A blood separation device adapted to receive a blood sample having a whole blood portion and a plasma portion is disclosed. The blood separation device includes a housing defining a first chamber, a second chamber, and a separation member disposed therebetween. The blood separation device also includes an actuator, wherein actuation of the actuator draws the blood sample into the first chamber and the separation member is adapted to allow the plasma portion to pass through the separation member to the second chamber. The blood separation device matches the plasma chamber volume, the blood chamber volume, and the applied single pressure source so that the correct trans-membrane pressure and shear rate is obtained.

Abstract: Microfluidic devices for cell sorting or cell fractionation are disclosed. A microfluidic device can comprise one or more inlets, a first wall and a second wall, and two or more outlets. The first and second walls can be substantially planar to each other and the first wall having can have a plurality of ridges protruding from the first wall and defining a compression gap between the ridge and a surface of the second wall. The microfluidic device can also be a cell sorting device for sorting a plurality of cells based on one or more biophysical cellular properties including size, elasticity, viscosity, and/or viscoelasticity wherein the cells are subjected to one or more compressions due to the compression gap. Also disclosed are methods for cell sorting based on a variety of biophysical cellular properties.

Abstract: A blood separation device adapted to receive a blood sample having a whole blood portion and a plasma portion is disclosed. The blood separation device includes a housing defining a first chamber, a second chamber, and a separation member disposed therebetween. The blood separation device also includes an actuator, wherein actuation of the actuator draws the blood sample into the first chamber and the separation member is adapted to allow the plasma portion to pass through the separation member to the second chamber. The blood separation device matches the plasma chamber volume, the blood chamber volume, and the applied single pressure source so that the correct trans-membrane pressure and shear rate is obtained.

Abstract: An apparatus for separating particles includes a first planar wall and a spaced apart second planar wall parallel to the first planar wall. The first planar wall and the second planar wall define a passage therebetween, which is disposed along a fluid flow axis. A first plurality of spaced apart elongated ridges extends into the passage from the first planar wall. The first plurality of spaced apart elongated ridges is disposed along a diagonal direction relative to the fluid flow axis. When a fluid is moved through the passage in a direction corresponding to the fluid flow axis, particles of a first type will tend to move in a first direction that is diagonally away from the fluid flow axis and particles of a second type, different from the first type, will tend to move in a second direction that is different from the first direction.

Abstract: An apparatus for separating particles includes a first planar wall and a spaced apart second planar wall parallel to the first planar wall. The first planar wall and the second planar wall define a passage therebetween, which is disposed along a fluid flow axis. A first plurality of spaced apart elongated ridges extends into the passage from the first planar wall. The first plurality of spaced apart elongated ridges is disposed along a diagonal direction relative to the fluid flow axis. When a fluid is moved through the passage in a direction corresponding to the fluid flow axis, particles of a first type will tend to move in a first direction that is diagonally away from the fluid flow axis and particles of a second type, different from the first type, will tend to move in a second direction that is different from the first direction.