Patents by Inventor Gonul Vardar

Gonul Vardar has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Directed evolution of recombinant monooxygenase nucleic acids and related polypeptides and methods of use
    Patent number: 7723498
    Abstract: The present invention relates to novel monooxygenase nucleic acids and polypeptides created using mutagenesis, DNA shuffling, or both, in a single iteration or multiple iterations, and methods for their creation and use. The monooxygenase enzymes of the present disclosure have particular utility as biocatalysts in industrial chemical redox reactions, such as the oxidation of aromatic hydrocarbons, for example, toluene, benzene, or nitrobenzene, into industrially desirable products. The systems and processes of the present invention are especially useful for the coupled synthesis and recovery of catechols, methylcatechols, resorcinols, methylresorcinols, hydroquinones, methylhydroquinones, hydroxybenzenes, cresols, nitrobenzenes, and nitrohydroxyquinones.
    Type: Grant
    Filed: June 3, 2005
    Date of Patent: May 25, 2010
    Assignee: University of Connecticut
    Inventors: Thomas K. Wood, Gonul Vardar
  • Directed evolution of recombinant monooxygenase nucleic acids and related polypeptides and methods of use
    Publication number: 20060051782
    Abstract: The present invention relates to novel monooxygenase nucleic acids and polypeptides created using mutagenesis, DNA shuffling, or both, in a single iteration or multiple iterations, and methods for their creation and use. The monooxygenase enzymes of the present disclosure have particular utility as biocatalysts in industrial chemical redox reactions, such as the oxidation of aromatic hydrocarbons, for example, toluene, benzene, or nitrobenzene, into industrially desirable products. The systems and processes of the present invention are especially useful for the coupled synthesis and recovery of catechols, methylcatechols, resorcinols, methylresorcinols, hydroquinones, methylhydroquinones, hydroxybenzenes, cresols, nitrobenzenes, and nitrohydroxyquinones.
    Type: Application
    Filed: June 3, 2005
    Publication date: March 9, 2006
    Inventors: Thomas Wood, Gonul Vardar