Patents by Inventor Gopadi M Venkatesh

Gopadi M Venkatesh has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Eprosartan arginyl charge-neutralization-complex and a process for its preparation and formulation
    Patent number: 6630498
    Abstract: This invention relates to (E)-&agr;-[2-n-butyl-1-[(4-carboxyphenyl)methyl]-1H-imidazol-5-yl]methylene-2-thiophenepropionic acid arginyl charge-neutralization-complex, a process for its production, compositions containing the compound and methods of using the compound to block angiotensin II receptors and to treat hypertension, congestive heart failure and renal failure.
    Type: Grant
    Filed: December 12, 2001
    Date of Patent: October 7, 2003
    Assignee: SmithKline Beecham Corporation
    Inventors: Manga R Gudipati, John M Jushchyshyn, Nageswara R Palepu, Gopadi M Venkatesh
  • High drug load immediate and modified release oral dosage formulations and processes for their manufacture
    Patent number: 6558699
    Abstract: This invention relates to high drug load granulation of (E)-&agr;-[2-n-butyl-1-[(4-carboxyphenyl)methyl]-1H-imidazol-5-yl]methylene-2-thiophenepropionic acid in the anhydrous form, a process for its production, compositions containing the compound and methods of using the compound to block angiotensin II receptors and to treat hypertension, congestive heart failure and renal failure.
    Type: Grant
    Filed: December 12, 2001
    Date of Patent: May 6, 2003
    Assignee: SmithKline Beecham Corporation
    Inventor: Gopadi M. Venkatesh
  • Bioenhanced formulations comprising eprosartan in oral solid dosage form
    Patent number: 6517871
    Abstract: This invention relates to bioenhanced formulations comprising eprosartan or eprosartan mesylate in the amorphous form, a process for its production, compositions containing the compound and methods of using the compound to block angiotensin II receptors and to treat hypertension, congestive heart failure and renal failure.
    Type: Grant
    Filed: May 23, 2001
    Date of Patent: February 11, 2003
    Assignee: SmithKline Beecham Corporation
    Inventors: Gopadi M. Venkatesh, Manga R. Gudipati
  • Carvedilol methanesulfonate
    Patent number: 6515010
    Abstract: This invention relates to carvedilol methanesulfonate, compositions containing this compound and methods of using carvedilol methanesulfonate to treat hypertension, congestive heart failure and angina.
    Type: Grant
    Filed: May 15, 2002
    Date of Patent: February 4, 2003
    Assignee: SmithKline Beecham Corporation
    Inventors: Miriam Franchini, Gopadi M. Venkatesh
  • Novel compositions of eprosartan
    Publication number: 20030022928
    Abstract: This invention relates to a novel composition comprising eprosartan, or a salt, solvate, or hydrate thereof, in particulate form, a process for its production and methods of using the composition to block angiotensin II receptors and to treat hypertension, congestive heart failure and renal failure.
    Type: Application
    Filed: August 6, 2002
    Publication date: January 30, 2003
    Applicant: SmithKline Beecham Corporation
    Inventor: Gopadi M. Venkatesh
  • Process for manufacturing bite-dispersion tablets
    Patent number: 6475510
    Abstract: This invention relates to a method for the manufacture of Bite-dispersion tablets which disperse easily and quickly in the oral cavity, after a gentle bite, without the aid of water, and if necessary includes masking the bitter taste of medicaments. The process comprises preparing a dry granulation of one or more of medicaments blended with suitable excipients, flavors and a combination of a waxy material and phospholipid (BMI-60) or an intense sweetener derived from fruit flavonoids (Neohesperidine) for taste-masking and compressing into tablets which can be packaged in bottles or blisters using conventional equipment.
    Type: Grant
    Filed: June 8, 2000
    Date of Patent: November 5, 2002
    Assignee: SmithKline Beecham Corporation
    Inventors: Gopadi M. Venkatesh, Nageswara R. Palepu
  • Eprosartan arginyl charge-neutralization-complex and a process for its preparation and formulation
    Publication number: 20020137943
    Abstract: This invention relates to (E)-&agr;-[2-n-butyl-1-[(4-carboxyphenyl)methyl]-1H-imidazol-5-yl]methylene-2-thiophenepropionic acid arginyl charge-neutralization-complex, a process for its production, compositions containing the compound and methods of using the compound to block angiotensin II receptors and to treat hypertension, congestive heart failure and renal failure.
    Type: Application
    Filed: December 12, 2001
    Publication date: September 26, 2002
    Inventors: Nageswara R. Palepu, Gopadi M. Venkatesh
  • High drug load immediate and modified release oral dosage formulations and processes for their manufacture
    Publication number: 20020098241
    Abstract: This invention relates to high drug load granulation of (E)-&agr;-[2-n-butyl-1-[(4-carboxyphenyl)methyl]-1H-imidazol-5-yl]methylene-2-thiophenepropionic acid in the anhydrous form, a process for its production, compositions containing the compound and methods of using the compound to block angiotensin II receptors and to treat hypertension, congestive heart failure and renal failure.
    Type: Application
    Filed: December 12, 2001
    Publication date: July 25, 2002
    Applicant: SmithKline Beecham Corporation
    Inventor: Gopadi M. Venkatesh
  • Eprosartan dihydate and a process for its production and formulation
    Patent number: 6420412
    Abstract: The invention relates to (E)-&agr;-[2-n-butyl-1-[(4-carboxyphenyl)methyl]-1-H-imidazol-5-yl]methylene-2-thiopheneproprionic acid monomethanesulfonate dihydrate, a process for its production, compositions containing the compound and methods of using the compound to block angiotensin II receptors and to treat hypertension, congestive heart failure and renal failure.
    Type: Grant
    Filed: March 15, 2001
    Date of Patent: July 16, 2002
    Assignee: SmithKline Beecham Corporation
    Inventors: Nageswara R. Palepu, Gopadi M. Venkatesh, Sarma Duddu
  • Controlled release solid dosage forms of lithium carbonate
    Patent number: 6365196
    Abstract: A process for preparing controlled release solid dosage forms of lithium carbonate by using a dissolution rate stabilizer and a hydrophobic waxy material.
    Type: Grant
    Filed: May 18, 2000
    Date of Patent: April 2, 2002
    Assignee: SmithKline Beecham Corporation
    Inventors: Gopadi M. Venkatesh, Nageswara R. Palepu
  • Eprosartan dihydate and a process for its production and formulation
    Publication number: 20010031877
    Abstract: The invention relates to (E)-&agr;-[2-n-butyl-1-[(4-carboxyphenyl)methyl]-1-H-imidazol-5-yl]methylene-2-thiopheneproprionic acid monomethanesulfonate dihydrate, a process for its production, compositions containing the compound and methods of using the compound to block angiotensin II receptors and to treat hypertension, congestive heart failure and renal failure.
    Type: Application
    Filed: March 15, 2001
    Publication date: October 18, 2001
    Applicant: SmithKline Beecham Corporation
    Inventors: Nageswara R. Palepu, Gopadi M. Venkatesh, Sarma Duddu
  • Eprosartan monohydrate
    Patent number: 6262102
    Abstract: This invention relates to (E)-&agr;-[2-n-butyl-1-[(4-carboxyphenyl)methyl]-1) H-imidazol-5-yl]methylene-2-thiophenepropionic acid monomethanfesulfonate monohydrate, compositions containing the compound and methods of using the compound to block angiotensin II receptors and to treat hypertension, congestive heart failure and renal failure.
    Type: Grant
    Filed: December 8, 1999
    Date of Patent: July 17, 2001
    Assignee: SmithKline Beecham Corporation
    Inventors: Sarma Duddu, Nageswara R Palepu, Gopadi M Venkatesh
  • Pharmaceutical thermal infusion process
    Patent number: 5827537
    Abstract: Invented are methods of transporting quantities of potassium clavulanate. Also invented are methods of forming a uniform continuous waxy barrier around medicament particles.
    Type: Grant
    Filed: May 25, 1995
    Date of Patent: October 27, 1998
    Assignee: SmithKline Beecham Corporation
    Inventors: Nageswara R. Palepu, Gopadi M. Venkatesh
  • Pharmaceutical thermal infusion granules
    Patent number: 5824344
    Abstract: Invented are controlled release formulations of medicaments for oral administration comprising a hydrophobic waxy material and prepared by thermal infusion.
    Type: Grant
    Filed: May 25, 1995
    Date of Patent: October 20, 1998
    Assignee: SmithKline Beecham Corporation
    Inventors: Nageswara R. Palepu, Gopadi M. Venkatesh
  • Pharmaceutical thermal infusion process
    Patent number: 5690959
    Abstract: A chewable tablet comprises a medicament dispersed in a chewable base, such as mannitol, together with an effervescent couple, such as citric acid--sodium bicarbonate. The combination of effervescence and chewability with optional flavorings improves the taste characteristics of the medicament in oral administration. A distintegrant such as microcrystalline cellulose may be added to give the patient the option of dispersing the tablet in water.
    Type: Grant
    Filed: May 4, 1995
    Date of Patent: November 25, 1997
    Assignee: SmithKline Beecham Corporation
    Inventors: Nageswara R. Palepu, Gopadi M. Venkatesh