Patents by Inventor Gopalan Raghunathan

Gopalan Raghunathan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Differentiation of Pluripotent Stem Cells
    Publication number: 20110091971
    Abstract: The present invention is directed to methods to differentiate pluripotent stem cells. In particular, the present invention is directed to methods and compositions to differentiate pluripotent stem cells into cells expressing markers characteristic of the definitive endoderm lineage. The present invention also provides methods to generate and purify agents capable of differentiating pluripotent stem cells into cells expressing markers characteristic of the definitive endoderm lineage.
    Type: Application
    Filed: June 29, 2009
    Publication date: April 21, 2011
    Inventors: Janet Davis, Jiajian Liu, Gopalan Raghunathan, Michael Joseph Hunter, Jose Pardinas, Judith Ann Connor, Ronald Vernon Swanson, Ellen Chi
  • Methods of Affinity Maturing Antibodies
    Publication number: 20110092372
    Abstract: The invention relates to methods of affinity maturing antibodies.
    Type: Application
    Filed: October 14, 2010
    Publication date: April 21, 2011
    Inventors: JUAN CARLOS ALMAGRO, JOHAN FRANSSON, GOPALAN RAGHUNATHAN
  • Anti-Respiratory Syncytial Virus Antibodies, Antigens and Uses Thereof
    Publication number: 20110027294
    Abstract: Anti-Respiratory Syncytial Virus (RSV) monoclonal antibodies, RSV F protein antigens and their uses are disclosed.
    Type: Application
    Filed: October 8, 2010
    Publication date: February 3, 2011
    Inventors: Alfred Delvecchio, Ping Tsui, Patrick Branigan, Leslee Conrad, Nicole Day, Changbao Liu, Raymond Sweet, Sheng-Jiun Wu, Jose Melero, Jinquan Luo, Gabriela Canziani, Mark Tornetta, Gopalan Raghunathan, Venkata Chalapathi Koka
  • Anti-TNF? antibodies and methods of use
    Patent number: 7790871
    Abstract: Novel TNF? antibody polypeptides and nucleic acids are disclosed. Methods of utilizing the polypeptides to treat TNF?-related diseases are also disclosed.
    Type: Grant
    Filed: August 11, 2008
    Date of Patent: September 7, 2010
    Inventors: Glen A. Evans, Katya McLane, Gopalan Raghunathan
  • ENGINEERED ANTI-IL-13 ANTIBODIES, COMPOSITIONS, METHODS AND USES
    Publication number: 20100111959
    Abstract: The present invention relates to engineered antibodies immunospecific for human interleukin-13 (IL-13) protein or fragment thereof, as well as methods of making and using thereof, including therapeutic indications.
    Type: Application
    Filed: August 12, 2009
    Publication date: May 6, 2010
    Inventors: Ronald V. Swanson, Ellen Chi, Gopalan Raghunathan, Shanrong Zhao, Johan Fransson, Wendy Cordier, Hong Mimi Zhou, Juan C. Almagro, Linus Hyun, Jill Giles-Komar, Karyn T. O'Neil, Jill M. Carton, Alexey V. Teplyakov
  • HUMAN ANTI-AMYLOID ANTIBODIES, COMPOSITIONS, METHODS AND USES
    Publication number: 20100074901
    Abstract: The present invention relates to at least one novel human anti-amyloid antibody, including isolated nucleic acids that encode at least one anti-amyloid antibody, amyloid, vectors, host cells, transgenic animals or plants, and methods of making and using thereof, including therapeutic compositions, methods and devices.
    Type: Application
    Filed: October 15, 2008
    Publication date: March 25, 2010
    Inventors: Marc Hubert Mercken, Jacqueline M. Benson, Sun-Yung S. Jung, Haiyan Jiang, Gopalan Raghunathan, Lionella Borozdina-Birch
  • Anti-TNF? antibodies
    Patent number: 7560108
    Abstract: Novel TNF? antibody polypeptides and nucleic acids are disclosed. Methods of utilizing the polypeptides to treat TNF?-related diseases are also disclosed.
    Type: Grant
    Filed: July 31, 2006
    Date of Patent: July 14, 2009
    Inventors: Glen A. Evans, Katya McLane, Gopalan Raghunathan
  • Methods for Use in Human-Adapting Monoclonal Antibodies
    Publication number: 20090118127
    Abstract: Methods useful for human adapting non-human monoclonal antibodies are disclosed. The methods select candidate human antibody framework sequences from a database of human germline genes or human sequences with somatic mutations.
    Type: Application
    Filed: October 19, 2007
    Publication date: May 7, 2009
    Inventor: Gopalan Raghunathan
  • Anti-TNFalpha Antibodies and Methods of Use
    Publication number: 20090012266
    Abstract: Novel TNF? antibody polypeptides and nucleic acids are disclosed. Methods of utilizing the polypeptides to treat TNF?-related diseases are also disclosed.
    Type: Application
    Filed: August 11, 2008
    Publication date: January 8, 2009
    Inventors: Glen A. Evans, Katya McLane, Gopalan Raghunathan
  • Anti-TNFalpha antibodies and methods of use
    Publication number: 20070092518
    Abstract: Novel TNF? antibody polypeptides and nucleic acids are disclosed. Methods of utilizing the polypeptides to treat TNF?-related diseases are also disclosed.
    Type: Application
    Filed: July 31, 2006
    Publication date: April 26, 2007
    Inventors: Glen Evans, Katya McLane, Gopalan Raghunathan
  • Anti-respiratory syncytial virus antibodies, antigens and uses thereof
    Publication number: 20060159695
    Abstract: Anti-Respiratory Syncytial Virus (RSV) monoclonal antibodies, RSV F protein antigens and their uses are disclosed.
    Type: Application
    Filed: October 28, 2005
    Publication date: July 20, 2006
    Inventors: Alfred Delvecchio, Ping Tsui, Patrick Branigan, Leslee Conrad, Nicole Day, Changbao Liu, Raymond Sweet, Sheng-Jiun Wu, Jose Melero, Jinquan Luo, Gabriela Canziani, Mark Tornetta, Gopalan Raghunathan, Venkata Koka
  • Toll like receptor 3 antagonists, methods and uses
    Publication number: 20060115475
    Abstract: Toll Like Receptor 3 (TLR3) antagonists, polynucleotides encoding TLR3 antagonists or fragments thereof, and methods of making and using the foregoing are disclosed.
    Type: Application
    Filed: November 30, 2005
    Publication date: June 1, 2006
    Inventors: Jill Carton, Shizhong Chen, Mark Cunningham, Anuk Das, Karen Duffy, Jill Giles-Komar, Theresa Goletz, David Knight, Roberta Lamb, Mouhamadou Mbow, Kristen Picha, Gopalan Raghunathan, Lani San Mateo, Robert Sarisky, Vedrana Stojanovic-Susulic, Nicole Stowell, Raymond Sweet, Shanrong Zhao