Patents by Inventor GOPI C. MOHAN

GOPI C. MOHAN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Composition and method for treatment of diseases associated with central nervous system inflammation
    Patent number: 11110078
    Abstract: The invention discloses compositions, methods and kits for use in treatment of diseases associated with CNS inflammation such as multiple sclerosis. The composition includes therapeutically effective amount of (1-H indazole-4yl-)methanol. Further, a method of inhibiting glial maturation factor beta (GMF-?) phosphorylation activity in cells is disclosed. The method of treating subjects includes administering a therapeutic effective amount of the composition. The administered composition suppresses the activity of the overexpressed GMF-? either by binding or blocking its phosphorylating sites and ameliorating the inflammatory condition. The disclosed compositions, methods and kits may be used in the treatment of diseases like multiple sclerosis, Alzheimer's disease, Parkinson's disease or cancer.
    Type: Grant
    Filed: March 25, 2019
    Date of Patent: September 7, 2021
    Assignee: AMRITA VISHWA VIDYAPEETHAM
    Inventors: Gopi C Mohan, Krishnakumar N Menon, Jane Jose
  • COMPOSITION AND METHOD FOR TREATMENT OF DISEASES ASSOCIATED WITH CENTRAL NERVOUS SYSTEM INFLAMMATION
    Publication number: 20190298695
    Abstract: The invention discloses compositions, methods and kits for use in treatment of diseases associated with CNS inflammation such as multiple sclerosis. The composition includes therapeutically effective amount of (1-H indazole-4yl-)methanol. Further, a method of inhibiting glial maturation factor beta (GMF-?) phosphorylation activity in cells is disclosed. The method of treating subjects includes administering a therapeutic effective amount of the composition. The administered composition suppresses the activity of the overexpressed GMF-? either by binding or blocking its phosphorylating sites and ameliorating the inflammatory condition. The disclosed compositions, methods and kits may be used in the treatment of diseases like multiple sclerosis, Alzheimer's disease, Parkinson's disease or cancer.
    Type: Application
    Filed: March 25, 2019
    Publication date: October 3, 2019
    Inventors: GOPI C. MOHAN, KRISHNAKUMAR N. MENON, JANE JOSE