Patents by Inventor Gopi Venkatesh

Gopi Venkatesh has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20140134246
    Abstract: Disclosed herein are pharmaceutically acceptable rapid dissolve vaginal tablet compositions comprising one or more active pharmaceutical ingredients suitable for therapy via topical action or systemic absorption, and methods of making and using such compositions.
    Type: Application
    Filed: November 1, 2013
    Publication date: May 15, 2014
    Applicant: Aptalis Pharmatech, Inc.
    Inventors: Gopi VENKATESH, Vijaya SWAMINATHAN, Jin-Wang LAI
  • Publication number: 20140050797
    Abstract: The present invention is directed to pharmaceutical compositions and dosage forms comprising TPR beads, wherein said TPR beads comprise a solid dispersion of at least one active pharmaceutical ingredient in at least one solubility-enhancing polymer, and a TPR coating comprising a water insoluble polymer and an enteric polymer, wherein the active pharmaceutical ingredient comprises a weakly basic active pharmaceutical ingredient having a solubility of not more than 100 ?g/mL at pH 6.8.
    Type: Application
    Filed: June 6, 2013
    Publication date: February 20, 2014
    Inventors: Gopi VENKATESH, Luigi BOLTRI, Italo COLOMBO, Jin-Wang LAI, Flavio FABIANI, Luigi MAPELLI
  • Publication number: 20120128764
    Abstract: The present invention relates to pharmaceutical compositions, and methods of preparing such compositions, comprising one or more populations of controlled-release particles comprising one or more proton pump inhibitors. The present invention also relates to pharmaceutical dosage forms, including orally disintegrating tablets, tablets, capsules, and methods for their preparation.
    Type: Application
    Filed: February 23, 2010
    Publication date: May 24, 2012
    Applicant: Aptalis Pharmatech, Inc.
    Inventors: Gopi Venkatesh, Michael Gosselin, Jin-Wang Lai, Christian Stollberg, Flavio Fabiani
  • Patent number: 8133506
    Abstract: The present invention is directed to pharmaceutical compositions, and methods of making such compositions, wherein the compositions comprise a plurality of TPR and RR particles, wherein: the TPR particles each comprise a core coated with a TPR layer; the core comprises a weakly basic, poorly soluble drug and a pharmaceutically acceptable organic acid separated from each other by an SR layer; the RR particles each comprise the weakly basic, poorly soluble drug, and release at least about 80 wt. % of the weakly basic, poorly soluble drug in about 5 minutes when dissolution tested using United States Pharmacopoeia (USP) dissolution methodology (Apparatus 2—paddles@50 RPM and a two-stage dissolution medium at 37° C. (first 2 hours in 0.1N HCl followed by testing in a buffer at pH 6.8).
    Type: Grant
    Filed: September 12, 2008
    Date of Patent: March 13, 2012
    Assignee: Aptalis Pharmatech, Inc.
    Inventors: Gopi Venkatesh, Jin-Wang Lai, Nehal H. Vyas, Vivek Purohit
  • Publication number: 20110311626
    Abstract: The present invention provides compositions comprising dicyclomine, or salts, and/or solvates and methods of making and using the compositions to treat intestinal hypermotility or Irritable Bowel Syndrome (IBS). The present invention also provides once-a-day orally disintegrating dosage forms comprising compositions of the present invention.
    Type: Application
    Filed: February 23, 2010
    Publication date: December 22, 2011
    Inventors: Gopi Venkatesh, Vincent Parrino, Paolo Gatti, Flavio Fabiani
  • Publication number: 20110217384
    Abstract: A unit dosage form, such as a capsule or the like, for delivering a skeletal muscle relaxant, such as cyclobenzaprine hydrochloride, into the body in an extended or sustained release fashion comprising one or more populations of drug-containing particles (beads, pellets, granules, etc.) is disclosed. At least one bead population exhibits a pre-designed sustained release profile. Such a drug delivery system is designed for once-daily oral administration to maintain an adequate plasma concentration—time profile, thereby providing relief of muscle spasm associated with painful musculoskeletal conditions over a 24 hour period.
    Type: Application
    Filed: August 31, 2010
    Publication date: September 8, 2011
    Inventors: Gopi Venkatesh, James M. Clevenger
  • Publication number: 20110081411
    Abstract: The present invention is directed to orally administered corticosteroid compositions. The present invention also provides a method for treating a condition associated with inflammation of the gastrointestinal tract in an individual. The method comprises administering to an individual in need thereof a pharmaceutical composition of the present invention.
    Type: Application
    Filed: October 1, 2010
    Publication date: April 7, 2011
    Inventors: Stephen Perrett, Fredric Jay Cohen, Gopi Venkatesh
  • Publication number: 20110064799
    Abstract: Compositions of the present invention, comprising the combination of enterically coated and uncoated pancreatic enzyme-containing beads are useful for treating or preventing pancreatitis pain, and optionally disorders associated with digestive enzyme deficiencies.
    Type: Application
    Filed: September 28, 2009
    Publication date: March 17, 2011
    Inventors: Stephen Perrett, Ruth Thieroff-Ekerdt, Gopi Venkatesh, Konstantinos Efthymiopoulos
  • Publication number: 20110003005
    Abstract: Extended release ondansetron compositions of the present invention are useful for treating postoperative nausea and vomiting (PONV) and/or postdischarge nausea and vomiting (PDNV).
    Type: Application
    Filed: January 15, 2010
    Publication date: January 6, 2011
    Inventors: Gopi Venkatesh, Stephen Perrett, Ruth Thieroff-Ekerdt
  • Publication number: 20110003006
    Abstract: The present invention is directed to pharmaceutical compositions comprising a plurality of taste-masked non-opioid analgesic/opioid analgesic drug-containing microparticles, dosage forms comprising such pharmaceutical compositions (such as an orally disintegrating tablet), and methods of making the pharmaceutical compositions and dosage forms of the present invention. Dosage forms comprising the pharmaceutical compositions of the present invention are improved homogeneous blends of non-opioid and opioid analgesics which provide for more convenient and palatable administration of drug combinations, for example for treating pain.
    Type: Application
    Filed: May 3, 2010
    Publication date: January 6, 2011
    Inventors: Gopi Venkatesh, Michael Gosselin, James Clevenger, Jin-Wang Lai
  • Publication number: 20100330150
    Abstract: The present invention is directed to pharmaceutical compositions comprising a plurality of taste-masked high-dose/low-dose drug-containing microparticles, dosage forms comprising such pharmaceutical compositions (such as an orally disintegrating tablet), and methods of making the pharmaceutical compositions and dosage forms of the present invention. Dosage forms comprising the pharmaceutical compositions of the present invention are improved homogeneous blends of high-dose and low-dose drugs which provide for more convenient and palatable administration of drug combinations, for example for treating pain, hyperglycemia, cardiovascular disease, and allergies.
    Type: Application
    Filed: May 3, 2010
    Publication date: December 30, 2010
    Inventors: Gopi Venkatesh, Michael Gosselin, James Clevenger, Jin-Wang Lai
  • Patent number: 7829121
    Abstract: A unit dosage form, such as a capsule or the like, for delivering a skeletal muscle relaxant, such as cyclobenzaprine hydrochloride, into the body in an extended or sustained release fashion comprising one or more populations of drug-containing particles (beads, pellets, granules, etc.) is disclosed. At least one bead population exhibits a pre-designed sustained release profile. Such a drug delivery system is designed for once-daily oral administration to maintain an adequate plasma concentration—time profile, thereby providing relief of muscle spasm associated with painful musculoskeletal conditions over a 24 hour period.
    Type: Grant
    Filed: September 24, 2008
    Date of Patent: November 9, 2010
    Assignee: Eurand Inc.
    Inventors: Gopi Venkatesh, James M. Clevenger
  • Patent number: 7820203
    Abstract: A unit dosage form, such as a capsule or the like, for delivering a skeletal muscle relaxant, such as cyclobenzaprine hydrochloride, into the body in an extended or sustained release fashion comprising one or more populations of drug-containing particles (beads, pellets, granules, etc.) is disclosed. At least one bead population exhibits a pre-designed sustained release profile. Such a drug delivery system is designed for once-daily oral administration to maintain an adequate plasma concentration—time profile, thereby providing relief of muscle spasm associated with painful musculoskeletal conditions over a 24 hour period.
    Type: Grant
    Filed: February 6, 2008
    Date of Patent: October 26, 2010
    Assignee: Eurand, Inc.
    Inventors: Gopi Venkatesh, James M. Clevenger
  • Patent number: 7790199
    Abstract: A unit dosage form, such as a capsule or the like, for delivering a skeletal muscle relaxant, such as cyclobenzaprine hydrochloride, into the body in an extended or sustained release fashion comprising one or more populations of drug-containing particles (beads, pellets, granules, etc.) is disclosed. At least one bead population exhibits a pre-designed sustained release profile. Such a drug delivery system is designed for once-daily oral administration to maintain an adequate plasma concentration—time profile, thereby providing relief of muscle spasm associated with painful musculoskeletal conditions over a 24 hour period.
    Type: Grant
    Filed: September 24, 2008
    Date of Patent: September 7, 2010
    Assignee: Eurand, Inc.
    Inventors: Gopi Venkatesh, James M. Clevenger
  • Patent number: 7632521
    Abstract: A unit dosage form, such as a tablet for delivering potassium into the body in a controlled release fashion, comprises of a multiplicity of microencapsulated potassium chloride crystals, which are further coated with a plasticized polymer to improve compressibility of the microcapsules. The compressible microcapsules are blended with a compression aid, such as microcrystalline cellulose and a glidant, such as colloidal silicon dioxide, to form controlled release potassium chloride tablets. The tablets may optionally include other excipients such as surfactants and disintegrants. The tablets thus produced exhibit not only high crushing strength and low friability but also release potassium in humans in a desired controlled release fashion similar to commercially available potassium chloride tablets.
    Type: Grant
    Filed: July 15, 2003
    Date of Patent: December 15, 2009
    Assignee: Eurand, Inc.
    Inventors: Gopi Venkatesh, Craig Kramer
  • Publication number: 20090258066
    Abstract: The present invention is directed to pharmaceutical compositions, and methods of making such compositions, comprising microparticles containing a weakly basic drug core, a layer of alkaline buffer, and a controlled-release coating. The present invention is also directed to pharmaceutical dosage forms, including orally disintegrating tablets, conventional tablets, and capsules, and methods for their preparation.
    Type: Application
    Filed: April 15, 2009
    Publication date: October 15, 2009
    Inventors: Gopi VENKATESH, Phillip J. Stevens, Jin-Wang Lai
  • Publication number: 20090232885
    Abstract: The present invention is directed to pharmaceutical compositions, and methods of making such compositions, wherein the compositions comprise a plurality of TPR and RR particles, wherein: the TPR particles each comprise a core coated with a TPR layer; the core comprises a weakly basic, poorly soluble drug and a pharmaceutically acceptable organic acid separated from each other by an SR layer; the RR particles each comprise the weakly basic, poorly soluble drug, and release at least about 80 wt.% of the weakly basic, poorly soluble drug in about 5 minutes when dissolution tested using United States Pharmacopoeia (USP) dissolution methodology (Apparatus 2—paddles@ 50 RPM and a two-stage dissolution medium at 37° C., (first 2 hours in 0.1N HCl followed by testing in a buffer at pH 6.8).
    Type: Application
    Filed: September 12, 2008
    Publication date: September 17, 2009
    Inventors: Gopi Venkatesh, Jin-Wang Lai, Nehal H. Vyas, Vivek Purohit
  • Publication number: 20090202630
    Abstract: The present invention is directed to pharmaceutical compositions comprising taste-masked microcapsules comprising ranitidine, orally disintegrating tablets comprising such compositions, and methods of making the pharmaceutical compositions and dosage forms of the present invention. The present invention is also directed to methods of administering the pharmaceutical compositions and orally disintegrating tablets to treat or prevent gastrointestinal disorders.
    Type: Application
    Filed: February 13, 2009
    Publication date: August 13, 2009
    Inventors: Gopi Venkatesh, Craig Kramer, Julius Dave King, JR., Bennie L. Young
  • Patent number: 7544372
    Abstract: A unit dosage form, such as a capsule or the like, for delivering a skeletal muscle relaxant, such as cyclobenzaprine hydrochloride, into the body in an extended or sustained release fashion comprising one or more populations of drug-containing particles (beads, pellets, granules, etc.) is disclosed. At least one bead population exhibits a pre-designed sustained release profile. Such a drug delivery system is designed for once-daily oral administration to maintain an adequate plasma concentration-time profile, thereby providing relief of muscle spasm associated with painful musculoskeletal conditions over a 24 hour period.
    Type: Grant
    Filed: February 6, 2008
    Date of Patent: June 9, 2009
    Assignee: Eurand, Inc.
    Inventors: Gopi Venkatesh, James M. Clevenger
  • Publication number: 20090017126
    Abstract: A unit dosage form, such as a capsule or the like, for delivering a skeletal muscle relaxant, such as cyclobenzaprine hydrochloride, into the body in an extended or sustained release fashion comprising one or more populations of drug-containing particles (beads, pellets, granules, etc.) is disclosed. At least one bead population exhibits a pre-designed sustained release profile. Such a drug delivery system is designed for once-daily oral administration to maintain an adequate plasma concentration—time profile, thereby providing relief of muscle spasm associated with painful musculoskeletal conditions over a 24 hour period.
    Type: Application
    Filed: September 24, 2008
    Publication date: January 15, 2009
    Inventors: Gopi Venkatesh, James M. Clevenger