Patents by Inventor Goran Eric Sundholm

Goran Eric Sundholm has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process
    Patent number: 7829123
    Abstract: A process for preparing particles of a substance, such as a protein or polypeptide, comprising: (a) preparing a first liquid comprising water, the substance and a modulator, wherein the modulator has a solubility in water which decreases with increasing temperature; and (b) contacting the first liquid with a second liquid comprising a fluid gas and an organic solvent using an anti-solvent fluid gas technique under conditions of temperature and pressure which result in the precipitation of particles comprising the substance, wherein the temperature of the first liquid is at or above the cloud point temperature of the first liquid when the first liquid contacts the second liquid. Also claimed are particles obtained according to the process and compositions containing the particles.
    Type: Grant
    Filed: September 15, 2006
    Date of Patent: November 9, 2010
    Assignee: AstraZeneca AB
    Inventors: Goran Eric Sundholm, Mustafa Demirbuker, Saeed Moshashaee
  • Process for preparing particles
    Patent number: 7108867
    Abstract: A process for preparing particles of a substance, such as a protein or polypeptide, comprising: (a) preparing a first liquid comprising water, the substance and a modulator, wherein the modulator has a solubility in water which decreases with increasing temperature; and (b) contacting the first liquid with a second liquid comprising a fluid gas and an organic solvent using an anti-solvent fluid gas technique under conditions of temperature and pressure which result in the precipitation of particles comprising the substance, wherein the temperature of the first liquid is at or above the cloud point temperature of the first liquid when the first liquid contacts the second liquid. Also claimed are particles obtained according to the process and compositions containing the particles.
    Type: Grant
    Filed: January 21, 2002
    Date of Patent: September 19, 2006
    Assignee: Astrazeneca AB
    Inventors: Goran Eric Sundholm, Mustafa Demirbuker, Saeed Moshashaee
  • Process for preparing particles
    Publication number: 20040058007
    Abstract: A process for preparing particles of a substance, such as a protein or polypeptide, comprising: (a) preparing a first liquid comprising water, the substance and a modulator, wherein the modulator has a solubility in water which decreases with increasing temperature; and (b) contacting the first liquid with a second liquid comprising a fluid gas and an organic solvent using an anti-solvent fluid gas technique under conditions of temperature and pressure which result in the precipitation of particles comprising the substance, wherein the temperature of the first liquid is at or above the cloud point temperature of the first liquid when the first liquid contacts the second liquid. Also claimed are particles obtained according to the process and compositions containing the particles.
    Type: Application
    Filed: July 8, 2003
    Publication date: March 25, 2004
    Inventors: Goran Eric Sundholm, Mustafa Demirbuker, Saeed Moshashaee