Patents by Inventor Goran KRILOV

Goran KRILOV has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Anti-malarial agents
    Patent number: 11903936
    Abstract: The present invention is related to new pyrrole derivatives in the manufacture of a medicament for preventing or treating malaria. Specifically, the present invention is related to pyrrole derivatives useful for the preparation of a pharmaceutical formulation for the inhibition of malaria parasite proliferation.
    Type: Grant
    Filed: December 18, 2020
    Date of Patent: February 20, 2024
    Assignees: THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM, MMV MEDICINES FOR MALARIA VENTURE
    Inventors: Margaret Phillips, Michael Palmer, Susan A. Charman, Karl Shawn Watts, Aleksey I. Gerasyuto, Goran Krilov
  • CYCLIC COMPOUNDS AND METHODS OF USING SAME
    Publication number: 20240018157
    Abstract: The present application relates to compounds of Formula (I), as defined herein, and pharmaceutically acceptable salts thereof which are MALT1 inhibitors. The present application also describes pharmaceutical composition comprising a compound of Formula (I), and pharmaceutically acceptable salts thereof, and methods of using the compounds and compositions for treating diseases, such as cancer, autoimmune disorders, and inflammatory disorders.
    Type: Application
    Filed: December 24, 2020
    Publication date: January 18, 2024
    Inventors: Shulu Feng, Morgan Lawrenz, Goran Krilov, Andrew Placzek, Zhe Nie, Lynnie Trzoss, Michael Trzoss, Haifeng Tang, H. Rachel Lagiakos
  • COMPOUND HAVING KDM5 INHIBITORY ACTIVITY AND PHARMACEUTICAL USE THEREOF
    Publication number: 20230271952
    Abstract: Disclosed are compounds of following formula (I): in which all symbols have the same meanings as the definitions described in the specification; or a salt thereof. The compounds or a salt thereof are useful as a prophylactic and/or therapeutic agent for cancer, Huntington's disease, Alzheimer's disease and the like.
    Type: Application
    Filed: May 5, 2023
    Publication date: August 31, 2023
    Applicant: ONO PHARMACEUTICAL CO., LTD.
    Inventors: Akito KAKUUCHI, Shuhei UMEMURA, Masaki ASADA, Anatoly RUVINSKY, Yan ZHANG, Hidenori TAKAHASHI, Goran KRILOV, Daigo INOYAMA, Kyle KONZE, Mats SVENSSON
  • Compound having KDM5 inhibitory activity and pharmaceutical use thereof
    Patent number: 11691968
    Abstract: Disclosed are compounds of following formula (I): in which all symbols have the same meanings as the definitions described in the specification; or a salt thereof. The compounds or a salt thereof are useful as a prophylactic and/or therapeutic agent for cancer, Huntington's disease, Alzheimer's disease and the like.
    Type: Grant
    Filed: October 24, 2022
    Date of Patent: July 4, 2023
    Assignee: ONO PHARMACEUTICAL CO., LTD.
    Inventors: Akito Kakuuchi, Shuhei Umemura, Masaki Asada, Anatoly Ruvinsky, Yan Zhang, Hidenori Takahashi, Goran Krilov, Daigo Inoyama, Kyle Konze, Mats Svensson
  • COMPOUND HAVING KDM5 INHIBITORY ACTIVITY AND PHARMACEUTICAL USE THEREOF
    Publication number: 20230109293
    Abstract: Disclosed are compounds of following formula (I): in which all symbols have the same meanings as the definitions described in the specification; or a salt thereof. The compounds or a salt thereof are useful as a prophylactic and/or therapeutic agent for cancer, Huntington's disease, Alzheimer's disease and the like.
    Type: Application
    Filed: October 24, 2022
    Publication date: April 6, 2023
    Applicant: ONO PHARMACEUTICAL CO., LTD.
    Inventors: Akito KAKUUCHI, Shuhei UMEMURA, Masaki ASADA, Anatoly RUVINSKY, Yan ZHANG, Hidenori TAKAHASHI, Goran KRILOV, Daigo INOYAMA, Kyle KONZE, Mats SVENSSON
  • ANTI-MALARIAL AGENTS
    Publication number: 20230056202
    Abstract: The present invention is related to new pyrrole derivatives in the manufacture of a medicament for preventing or treating malaria. Specifically, the present invention is related to pyrrole derivatives useful for the preparation of a pharmaceutical formulation for the inhibition of malaria parasite proliferation.
    Type: Application
    Filed: December 18, 2020
    Publication date: February 23, 2023
    Inventors: MARGARET PHILLIPS, MICHAEL PALMER, SUSAN A. CHARMAN, KARL SHAWN WATTS, ALEKSEY I. GERASYUTO, GORAN KRILOV
  • COMPOUND HAVING KDM5 INHIBITORY ACTIVITY AND PHARMACEUTICAL USE THEREOF
    Publication number: 20220289751
    Abstract: The compound disclosed is a KDM5 inhibitor represented by the general formula (Z): wherein all symbols have the same meanings as the definitions described in the specification, or a salt thereof, and is useful as a prophylactic and/or therapeutic agent for cancer, Huntington's disease, or Alzheimer's disease and the like.
    Type: Application
    Filed: July 16, 2020
    Publication date: September 15, 2022
    Applicant: ONO PHARMACEUTICAL CO., LTD.
    Inventors: Akito KAKUUCHI, Shuhei UMEMURA, Mats SVENSSON, Anatoly RUVINSKY, Daigo INOYAMA, Goran KRILOV, Hidenori TAKAHASHI, Kyle KONZE, Andreas VERRAS, Simon CRUMPLER, Maelle VALLADE, Calum MACLEOD, James N. SANDERSON, Richard J. BULL, Simon GAINES