Patents by Inventor Gordon A. Vehar

Gordon A. Vehar has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Preparation of functional human factor VIII in mammalian cells using methotrexate based selection
    Patent number: 4965199
    Abstract: A method for producing factor VIII in recombinant mammalian host cells utilizing an expression vector containing a selectable marker DNA and an amplifiable marker DNA. The initial selection is based upon the selectable marker and subsequent amplification of factor VIII DNA and amplifiable marker DNA is conducted in cells not deficient in the amplifiable marker.
    Type: Grant
    Filed: August 7, 1987
    Date of Patent: October 23, 1990
    Assignee: Genentech, Inc.
    Inventors: Daniel J. Capon, Richard M. Lawn, Arthur D. Levinson, Gordon A. Vehar, William I. Wood
  • Human tissue plasminogen activator
    Patent number: 4853330
    Abstract: Human tissue plasminogen activator (t-PA) is produced in useful quantities using recombinant DNA techniques. The invention disclosed thus enables the production of t-PA free of contaminants with which it is ordinarily associated in its native cellular environment. Methods, expression vehicles and various host cells useful in its production are also disclosed.
    Type: Grant
    Filed: April 21, 1988
    Date of Patent: August 1, 1989
    Assignee: Genentech, Inc.
    Inventors: David V. Goeddel, William J. Kohr, Diane Pennica, Gordon A. Vehar
  • Human tissue plasminogen activator
    Patent number: 4766075
    Abstract: Human tissue phasminogen activator (t-PA) is produced in useful quantities using recombinant DNA techniques. The invention disclosed thus enables the production of t-PA free of contaminants with which it is ordinarily associated in its native cellular environment. Methods, expression vehicles and various host cells useful in its production are also disclosed.
    Type: Grant
    Filed: April 7, 1983
    Date of Patent: August 23, 1988
    Assignee: Genentech, Inc.
    Inventors: David V. Goeddel, William J. Kohr, Diane Pennica, Gordon A. Vehar