Abstract: Provided herein are KRAS G12C inhibitors, composition of the same, and methods of using the same. These inhibitors are useful for treating a number of disorders, including pancreatic, colorectal, and lung cancers.

Abstract: Embodiments included herein are directed towards an apparatus and method for use with an alert management system. Embodiments may include scanning, using an imaging device including radio frequency imaging based on frequency-modulated continuous-wave radar. The imaging device may include ultrasonic imaging capabilities and metal detecting capabilities. Embodiments may include detecting a metallic object associated with an individual and capturing an image of both the individual and the detected metallic object. Embodiments may further include sending a warning signal to a nearest access point which transmits the information to a network and processing the information by the software or application at a local security point.

Abstract: An alert device, a method of using an alert device, and a personnel security system including an alert device. The alert device includes an attachment mechanism and a housing coupled together. The housing is configured to transmit a signal. The method of using an alert device includes releasably attaching an alert device to a human body, activating a sensor on the alert device, generating an alert from the alert device, receiving the alert in a receiver, identifying a location of the alert device based at least in part on a location of the receiver, and providing notification of the alert and the location of the alert device.

Abstract: The present invention relates to RNAi constructs for reducing expression of the ASGR1 gene. Methods of using such RNAi constructs to treat or prevent cardiovascular disease, such as coronary artery disease and myocardial infarction, and to reduce serum non-HDL cholesterol levels are also described.

Abstract: Provided herein are KRAS G12C inhibitors, composition of the same, and methods of using the same. These inhibitors are useful for treating a number of disorders, including pancreatic, colorectal, and lung cancers.

Abstract: The present invention relates to RNAi constructs for reducing expression of the ASGR1 gene. Methods of using such RNAi constructs to treat or prevent cardiovascular disease, such as coronary artery disease and myocardial infarction, and to reduce serum non-HDL cholesterol levels are also described.

Abstract: An alert communication device, an alert activation device, and an alert management system are provided. The alert management system may include one or more alert communication devices communicatively coupled to one or more other alert communication devices and configured to provide one or more of a visual alert and an audio alert and one or more alert activation devices communicatively coupled to at least one alert communication device of the one or more alert communication devices.

Abstract: An alert communication device, an alert activation device, and an alert management system are provided. The alert management system may include one or more alert communication devices communicatively coupled to one or more other alert communication devices and configured to provide one or more of a visual alert and an audio alert and one or more alert activation devices communicatively coupled to at least one alert communication device of the one or more alert communication devices.

Abstract: An alert communication device, an alert activation device, and an alert management system are provided. The alert management system may include one or more alert communication devices communicatively coupled to one or more other alert communication devices and configured to provide one or more of a visual alert and an audio alert and one or more alert activation devices communicatively coupled to at least one alert communication device of the one or more alert communication devices.

Abstract: An alert communication device, an alert activation device, and an alert management system are provided. The alert management system may include one or more alert communication devices communicatively coupled to one or more other alert communication devices and configured to provide one or more of a visual alert and an audio alert and one or more alert activation devices communicatively coupled to at least one alert communication device of the one or more alert communication devices.

Abstract: Provided herein are methods of using KRAS G12C inhibitors and compositions of the same. These inhibitors are useful for treating a number of disorders, including pancreatic, colorectal, and lung cancers.

Abstract: Provided herein are KRAS G12C inhibitors, such as composition of the same, and methods of using the same. These inhibitors are useful for treating a number of disorders, including pancreatic, colorectal, and lung cancers.

Abstract: Provided herein are KRAS G12C inhibitors, composition of the same, and methods of using the same. These inhibitors are useful for treating a number of disorders, including pancreatic, colorectal, and lung cancers.

Abstract: Provided herein are KRAS G12C inhibitors, such as composition of the same, and methods of using the same. These inhibitors are useful for treating a number of disorders, including pancreatic, colorectal, and lung cancers.

Abstract: Provided herein are KRAS G12C inhibitors, composition of the same, and methods of using the same. These inhibitors are useful for treating a number of disorders, including pancreatic, colorectal, and lung cancers.

Abstract: The present invention relates to RNAi constructs for reducing expression of the ASGR1 gene. Methods of using such RNAi constructs to treat or prevent cardiovascular disease, such as coronary artery disease and myocardial infarction, and to reduce serum non-HDL cholesterol levels are also described.

Abstract: An alert communication device, an alert activation device, and an alert management system are provided. The alert management system may include one or more alert communication devices communicatively coupled to one or more other alert communication devices and configured to provide one or more of a visual alert and an audio alert and one or more alert activation devices communicatively coupled to at least one alert communication device of the one or more alert communication devices.

Abstract: An alert communication device, an alert activation device, and an alert management system are provided. The alert management system may include one or more alert communication devices communicatively coupled to one or more other alert communication devices and configured to provide one or more of a visual alert and an audio alert and one or more alert activation devices communicatively coupled to at least one alert communication device of the one or more alert communication devices.

Abstract: Included are embodiments of a system for monitoring device usage. The system may include a handheld device for performing an action, where the handheld device includes an engagement sensor and a computer that includes a processor and a memory component. The memory component stores logic that causes the computer to determine a minimum device engagement time of the handheld device. In some embodiments, the logic causes the computer to receive output data from the engagement sensor, where the output data includes an actual device engagement time, determine if the actual device engagement time is at least as long as the minimum device engagement time, and in response to determining that the actual device engagement time is at least as long as the minimum device engagement time, determine the action taken by the handheld device.

Abstract: Provided herein are KRAS G12C inhibitors, composition of the same, and methods of using the same. These inhibitors are useful for treating a number of disorders, including pancreatic, colorectal, and lung cancers.