Patents by Inventor Gordon C. Lawrence

Gordon C. Lawrence has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5378617
    Abstract: A process for the production of a compound of formula (I) ##STR1## which comprises cultivating a microorganism of the genus Streptomyces capable of producing the compound of formula (I) in the presence of one or more fatty acids and/or salts, esters and amides of these acids, whereby the compound of formula (I) is produced, and if desired isolating the said compound. The fatty acid increases the yield of the formula (I) compound and is preferably isobutyric or valeric acid.
    Type: Grant
    Filed: August 24, 1992
    Date of Patent: January 3, 1995
    Assignee: American Cyanamid Company
    Inventors: Martin Todd, Mark A. Haxell, Gordon C. Lawrence
  • Patent number: 5116968
    Abstract: Compounds of formula (1) ##STR1## wherein R represents a sugar residue or an acylated derivative thereof;R.sup.1 represents a methyl, ethyl or isopropyl group;Y.sup.1 is --CH.sub.2, Y.sup.2 is --CH-- and X represents ##STR2## [wherein R.sup.2 represents a hydrogen atom or a group OR.sup.6 (where OR.sup.6 is a hydroxyl group or a substituted hydroxyl group having up to 25 carbon atoms) and R.sup.3 represents a hydrogen atom, or R.sup.2 and R.sup.3 together with the carbon atom to which they are attached represent >C.dbd.0, >C.dbd.CH.sub.2 or >C.dbd.NOR.sup.7 (where R.sup.7 represents a hydrogen atom, a C.sub.1-8 alkyl group or a C.sub.3-8 alkenyl group) and the group >C.dbd.NOR.sup.7 is in the E configuration] or --Y.sup.1 --X--Y.sup.2 -- represents --CH.dbd.CH--CH-- or --CH.sub.2 --CH.dbd.C--; andR.sup.4 represents a group OR.sup.6 as defined above and R.sup.5 represents a hydrogen atom, or R.sup.4 and R.sup.5 together with the carbon atom to which the are attached represent >C.dbd.0 or >C.
    Type: Grant
    Filed: December 20, 1990
    Date of Patent: May 26, 1992
    Assignee: American Cyanamid Company
    Inventors: Gordon C. Lawrence, Michael J. Dawson, David Noble, Michael V. J. Ramsay, Richard Bell, Derek R. Sutherland, Edward P. Tiley
  • Patent number: 5108992
    Abstract: Compounds of formula (1) ##STR1## and their salts, wherein R.sup.1 is a methyl, ethyl or isopropyl group each substituted by a hydroxyl group or R.sup.1 is a group --(CH.sub.2).sub.n R7 or a group --CH(CH.sub.3)R.sup.7 (where n is zero or 1 and R.sup.7 l is CHO or CO.sub.2 H);Y.sup.1 is --CH.sub.2 --, Y.sup.2 is --CH-- and X represents ##STR2## [where R.sup.2 is a hydrogen atom or a group OR.sup.8 is a hydroxyl group or a substituted hydroxyl group having up to 25 carbon atoms) and R.sup.3 is a hydrogen atom, or R.sup.2 and R.sup.3 together with the carbon atom to which they are attached represent >.dbd.O, >C.dbd.CH.sub.2 or >C.dbd.NOR.sup.9 (where R.sup.9 is a hydrogen atom or a C.sub.1-8 alkyl or C.sub.3-8 alkenyl group) and the group >C.dbd.NOR.sup.9 is in the E configuration] or --Y.sup.1 --X--Y.sup.2 -- represents --CH.dbd.CH--CH-- or --CH.sub.2 --CH.dbd.C--;R.sup.4 is a group OR.sup.8 as defined above and R.sup.5 is a hydrogen atom, or R.sup.4 and R.sup.
    Type: Grant
    Filed: December 20, 1990
    Date of Patent: April 28, 1992
    Assignee: American Cyanamid Company
    Inventors: Gordon C. Lawrence, Michael J. Dawson, David Noble, Richard A. Fletton, Stephen J. Lane
  • Patent number: 5057536
    Abstract: Compounds of formula (1) ##STR1## and salts thereof, wherein R.sup.1 represents a methyl, ethyl or isopropyl group;Y.sup.1 is --CH.sub.2 --, Y.sup.2 is --CH-- and X represents ##STR2## where R.sup.2 represents a hydrogen atom or a group OR.sup.8 (where OR.sup.8 is a hydroxyl group or a substituted hydroxyl group having up to 25 carbon atoms) and R.sup.3 represents a hydrogen atom, or R.sup.2 and R.sup.3 together with the carbon atom to which they are attached represent >C.dbd.O, >C.dbd.CH.sub.2 or >C.dbd.NOR.sup.9 (where R.sup.9 represents a hydrogen atom, a C.sub.1-8 alkyl group or a C.sub.3-8 alkenyl group) and the group >C.dbd.NOR.sup.9 is in the E configuration] or --Y.sup.1 --X--Y.sup.2 -- represents --CH.dbd.CH--CH-- or --CH.sub.2 --CH.dbd.C--;R.sup.4 represents a group OR.sup.8 as defined above and R.sup.5 represents a hydrogen atom, or R.sup.4 and R.sup.5 together with the carbon atom to which they are attached represent >C.dbd.O or >C.dbd.NOR.sup.9a (where R.sup.
    Type: Grant
    Filed: May 9, 1989
    Date of Patent: October 15, 1991
    Assignee: American Cyanamid Company
    Inventors: Michael J. Dawson, David Noble, Gordon C. Lawrence, Richard A. Fletton, Stephen J. Lane, Michael V. J. Ramsay, Oswy Z. Pereira, Derek R. Sutherland, Edward P. Tiley