Patents by Inventor Gordon Duane Holt

Gordon Duane Holt has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Proteins, genes and their use for diagnosis and treatment of kidney response
    Publication number: 20040053309
    Abstract: The present invention provides methods and compositions for screening, diagnosis and prognosis of kidney response, for monitoring the effectiveness of kidney response treatment, identifying patients most likely to respond to a particular therapeutic treatment and for drug development. In particular, the screening of drug candidates for their ability to induce a kidney response. Kidney Response-Associated Features (KRFs), detectable by two-dimensional electrophoresis of blood, serum, plasma or kidney tissue are described. The invention further provides Kidney Response-Associated Protein Isoforms (KRPIs) detectable in blood, serum, plasma or kidney tissue, preparations comprising isolated KRPIs, antibodies immunospecific for KRPIs, and kits comprising the aforesaid.
    Type: Application
    Filed: June 23, 2003
    Publication date: March 18, 2004
    Inventors: Gordon Duane Holt, Michael Douglas Kelly, Sandra Jane Kennedy, Christopher Moyses
  • Biomarkers of liver response
    Publication number: 20030228583
    Abstract: The present invention provides methods and compositions for screening, diagnosing and prognosing liver response, for monitoring the effectiveness of liver response treatment, and for drug development.
    Type: Application
    Filed: October 31, 2002
    Publication date: December 11, 2003
    Inventors: David E. Amacher, Lisa M. Fasulo, Herath Mudiyanselage Athula Chandrasiri Herath, Gordon Duane Holt, Thomas R. Stiger
  • Proteins, genes and their use for diagnosis and treatment of cardiac response
    Publication number: 20030092197
    Abstract: The present invention provides methods and compositions for screening, diagnosis and prognosis of Cardiac Response, for monitoring the effectiveness of Cardiac Response treatment and for drug development. Cardiac Response-Associated Features (CRFs) detectable by two-dimensional electrophoresis of blood are described. The invention further provides Cardiac Response-Associated Protein Isoforms (CRPIs) detectable in biological sample preparations comprising isolated CRPIs, antibodies specific for CRPIs and kits comprising the aforesaid.
    Type: Application
    Filed: December 27, 2001
    Publication date: May 15, 2003
    Inventors: Eugene Herman, Gordon Duane Holt, Frank Sistare, Jun Zhang
  • Proteins, genes and their use for diagnosis and treatment of vascular response
    Publication number: 20030049640
    Abstract: The present invention provides methods and compositions for screening, diagnosis and prognosis of vascular response, for monitoring the effectiveness of vascular response treatment, identifying patients most likely to respond to a particular therapeutic treatment and for drug development. In particular, the screening of drug candidates for their ability to induce a vascular response. Vascular Response-Associated Features (VRFs), detectable by two-dimensional electrophoresis of blood, serum or plasma are described. The invention further provides Vascular Response-Associated Protein Isoforms (VRPIs) detectable in blood, serum or plasma, preparations comprising isolated VRPIs, antibodies immunospecific for VRPIs, and kits comprising the aforesaid.
    Type: Application
    Filed: December 27, 2001
    Publication date: March 13, 2003
    Inventors: Eugene Herman, Gordon Duane Holt, Frank Sistare, Jun Zhang