Patents by Inventor Gordon E. Olsen

Gordon E. Olsen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Heteroarylamino- and heteroaryloxypyridinamine compounds which have useful utility in treating skin disorders
    Patent number: 4970219
    Abstract: There are described compounds of the formula ##STR1## where n is 0 or 1;X is O or NR.sub.2,R.sub.2 being hydrogen, loweralkyl or loweralkylcarbonyl;R is hydrogen, loweralkyl, arylloweralkyl or loweralkylcarbonyl; and R.sub.1 is ##STR2## wherein R.sub.3 is hydrogen, loweralkyl or loweralkylcarbonyl; which compounds are useful as topical antiinflammatory agents for the treatment of various dermatoses.
    Type: Grant
    Filed: June 28, 1989
    Date of Patent: November 13, 1990
    Assignee: Hoechst-Roussel Pharmaceuticals Inc.
    Inventors: Richard C. Effland, Joseph T. Klein, Gordon E. Olsen, Larry Davis
  • N-(pyridinyl)-1H-indol-1-amines
    Patent number: 4970218
    Abstract: There are disclosed compounds of the formula, ##STR1## where m, n, p, R, R.sub.1, R.sub.2 and R.sub.3 are as defined in the specification; which compounds are useful for enhancing memory and also as analgesic and antidepressant agents.
    Type: Grant
    Filed: September 11, 1989
    Date of Patent: November 13, 1990
    Assignee: Hoechst-Roussel Pharmaceuticals Inc.
    Inventors: Richard C. Effland, Joseph T. Klein, Larry Davis, Gordon E. Olsen
  • Phenoxypyridinamine compounds which are use as a dermatological composition
    Patent number: 4959377
    Abstract: There are described compounds of the formula ##STR1## where n is 0 or 1;X is hydrogen, loweralkyl, loweralkoxy, halogen, formyl, loweralkylcarbonyl, loweralkyoxycarbonyl, loweralkoxycarbonylloweralkyl or hydroxymethyl;Y is hydrogen or halogen;andR is hydrogen, loweralkyl arylloweralkyl or loweralkylcarbonyl,which compounds are useful as topical antiinflammatory agents for the treatment of various dermatoses.
    Type: Grant
    Filed: June 29, 1989
    Date of Patent: September 25, 1990
    Assignee: Hoechst-Roussel Pharmaceuticals Inc.
    Inventors: Richard C. Effland, Joseph T. Klein, Gordon E. Olsen, Larry Davis
  • 4-pentafluorophenoxypiperidines
    Patent number: 4954511
    Abstract: 4-Phenafluorophenoxypiperidines and methods for alleviating pain and treating depression, convulsions, and hypertension utilizing compounds or compositions thereof are disclosed.
    Type: Grant
    Filed: January 24, 1990
    Date of Patent: September 4, 1990
    Assignee: Hoechst-Roussell Pharmaceuticals Inc.
    Inventors: Grover C. Helsley, Larry Davis, Gordon E. Olsen
  • Naphthylamino-and naphthyloxy-pyridinamine comounds useful as topical antiinflammatory agents for the treatment of skin disorders
    Patent number: 4931457
    Abstract: There are described compounds of the formula ##STR1## where R is hydrogen, loweralkyl, arylloweralkyl or loweralkylcarbonyl;X is O or NR.sub.1, R.sub.1 being hydrogen, loweralkyl or loweralkylcarbonyl; andY is hydrogen, loweralkyl, loweralkoxy, halogen or trifluoromethyl;which compounds are useful as topical antiinflammatory agents for the treatment of skin disorders.
    Type: Grant
    Filed: June 28, 1989
    Date of Patent: June 5, 1990
    Assignee: Hoechst-Roussel Pharmaceuticals Inc.
    Inventors: Richard C. Effland, Joseph T. Klein, Gordon E. Olsen, Larry Davis
  • N-heteroaryl-4-quinolinamines
    Patent number: 4916135
    Abstract: There are described compounds of the formula ##STR1## where --R is ##STR2## --R.sub.3 and R.sub.3 being independently --H, loweralkyl, --CHO, --CH.dbd.CH.sub.2, --CH.dbd.CH--loweralkyl, --CH.dbd.CHCO.sub.2 C.sub.2 H.sub.5, --CH.sub.2 N(C.sub.2 H.sub.5).sub.2 or ##STR3## --R.sub.1 when existent is --H, loweralkyl, --CH.sub.2 C.tbd.CH, ##STR4## R.sub.5 being methyl or phenyl optionally mono-substituted with loweralkyl or loweralkoxy;--R.sub.2 when existent is loweralkyl or --CH.sub.2 C.tbd.CH;--X is --H, loweralkyl, loweralkoxy, halogen or trifluoromethyl; and the two --Y groups when existent are both --H, or combine to constitute --(CH.sub.2).sub.4 --;which compounds are useful as analgesic agents, and for treating various memory dysfunctions characterized by decreased cholinergic function such as Alzheimer's disease.
    Type: Grant
    Filed: May 8, 1989
    Date of Patent: April 10, 1990
    Assignee: Hoechst Roussel Pharmaceuticals Inc.
    Inventors: Richard C. Effland, Joseph T. Klein, Larry Davis, Gordon E. Olsen
  • 3-(2,3,4,5,6-pentafluorophenoxy)-8-azabicyclo(3.2.1)octanes
    Patent number: 4916139
    Abstract: 3-(2,3,4,5,6-pentafluorophenoxy)-8-azabicyclo[3.2.1]octanes and methods for treating depression, convulsions, pain, and hypertension utilizing compounds or compositions thereof are disclosed.
    Type: Grant
    Filed: June 7, 1989
    Date of Patent: April 10, 1990
    Assignee: Hoechst-Roussel Pharmaceuticals, Inc.
    Inventors: Grover C. Helsley, Larry Davis, Gordon E. Olsen
  • Pyrido(3,4-F)pyrrolo(1,2-B)(1,2,5)triazepines
    Patent number: 4914103
    Abstract: Pyrido[3,4-f]pyrrolo[1,2-b][1,2,5]triazepines and methods for treating depression, alleviating pain and inflammation, and enhancing memory utilizing compounds or compositions thereof are disclosed.
    Type: Grant
    Filed: August 24, 1989
    Date of Patent: April 3, 1990
    Assignee: Hoechst-Roussel Pharmaceuticals Inc.
    Inventors: Richard C. Effland, Larry Davis, Kevin J. Kapples, Gordon E. Olsen
  • 4-Pentafluorophenoxypiperidines
    Patent number: 4914204
    Abstract: 4-Pentafluorophenoxypiperidines and methods for alleviating pain and treating depression, convulsions, and hypertension utilizing compounds or compositions thereof are disclosed.
    Type: Grant
    Filed: March 14, 1988
    Date of Patent: April 3, 1990
    Assignee: Hoechst-Roussel Pharmaceuticals Incorporated
    Inventors: Grover C. Helsley, Larry Davis, Gordon E. Olsen
  • Pyrido(3,4-f)pyrrolo(1,2-b)(1,2,5)triazepines
    Patent number: 4879382
    Abstract: Pyrido[3,4-f]pyrrolo[1,2-b][1,2]triazepines and methods for treating depression, alleviating pain and inflammation, and enhancing memory utilizing compounds or compositions thereof are disclosed.
    Type: Grant
    Filed: July 25, 1988
    Date of Patent: November 7, 1989
    Assignee: Hoechst-Roussel Pharmaceuticals, Inc.
    Inventors: Richard C. Effland, Larry Davis, Kevin J. Kapples, Gordon E. Olsen
  • N-pyridinyl-9H-carbazol-9-amines
    Patent number: 4868190
    Abstract: There are described compounds of the formula: ##STR1## where, X is hydrogen, loweralkyl, loweralkoxy or halogen;Y is hydrogen, loweralkyl or halogen;Z is hydrogen, loweralkyl or halogen;R is hydrogen, loweralkyl, loweralkenyl, loweralkylcarbonyl, dimethylaminoloweralkyl or ##STR2## m being an integer of 1 to 6, with the proviso that when R is loweralkenyl the double bond is not alpha to the nitrogen atom;which compounds are useful analgesic, anticonvulsant and antidepressant agents, and for treating various memory dysfunctions characterized by decreased cholinergic function such as Alzheimer's disease.
    Type: Grant
    Filed: December 27, 1988
    Date of Patent: September 19, 1989
    Assignee: Hoechst-Roussel Pharmaceuticals, Inc.
    Inventors: Richard C. Effland, Joseph T. Klein, Larry Davis, Gordon E. Olsen
  • 3-(2,3,4,5,6-pentafluorophenoxy)-8-azabicyclo[3.2.1]octanes
    Patent number: 4861889
    Abstract: 3-(2,3,4,5,6-pentafluorophenoxy)-8-azabicyclo[3.2.1]octanes and methods for treating depression, convulsions, pain, and hypertension utilizing compounds or compositions thereof are disclosed.
    Type: Grant
    Filed: March 14, 1988
    Date of Patent: August 29, 1989
    Assignee: Hoechst-Roussel Pharmaceuticals, Inc.
    Inventors: Grover C. Helsley, Larry Davis, Gordon E. Olsen
  • 1-carbonyl derivatives of 4-aryl-4-aryloxypiperidines
    Patent number: 4853384
    Abstract: 1-Carbonyl derivatives of 4-aryl-4-aryloxypiperidines and methods for alleviating pain and treating convulsions utilizing compounds or compositions thereof are disclosed.
    Type: Grant
    Filed: March 14, 1988
    Date of Patent: August 1, 1989
    Assignee: Hoechst-Roussel Pharmaceuticals Inc.
    Inventors: Grover C. Helsley, Larry Davis, Gordon E. Olsen
  • 1-((Phenothiazin-10-yl)alkyl)-alpha-phenyl-4-piperidinemethanols and pharmaceutical use
    Patent number: 4822796
    Abstract: 1-[(phenothiazin-10-yl)alkyl]-.alpha.-phenyl-4-piperidinemethanols and methods for treating pain or psychosis utilizing compounds or compositions thereof are disclosed.
    Type: Grant
    Filed: June 1, 1987
    Date of Patent: April 18, 1989
    Inventors: Grover C. Helsley, Larry Davis, Gordon E. Olsen
  • 1-(N-(2-alkylthio-10H-phenothiazin-10-yl)alkyl)-4-benzoylpiperidines and pharmaceutical use
    Patent number: 4812456
    Abstract: This invention relates to 1-[n-(2-alkylthio-10H-phenothiazin-10-yl)alkyl]-4-benzoylpiperidines and methods for treating pain or psychosis utilizing compounds or compositions thereof.
    Type: Grant
    Filed: May 13, 1987
    Date of Patent: March 14, 1989
    Assignee: Hoechst-Roussel Pharmaceuticals Inc.
    Inventors: Grover C. Helsley, Larry Davis, Gordon E. Olsen