Abstract: An adhesive oral disc for sustained release of cannabinoids is presented. The disc includes one or more cannabinoids and is composed of at least a mucosal contacting layer having a mucosal contacting surface operable to be fixed to the gingiva of a person in need of alleviation or treatment of a medical condition, where the mucosal contacting layer includes one or more mucoadhesive polymers allowing the adhesive oral disc to adhere to the gingiva for an extended period of time. Further, the disc includes a non-mucoadhesive module fused to the mucosal contacting layer, where the non-mucoadhesive module includes a solid tablet composition allowing the non-mucoadhesive module to dissolve within an extended period of time upon adhesion of the adhesive oral disc to the gingiva. The invention is particularly useful for alleviation or treatment of ulcers.

Abstract: A caged phosphine product is provided which can act as a ligand to form a metal complex. The metal complex can be used as a catalyst.

Abstract: Halogenated phosphines are produced by reacting a secondary phosphine with a quaternary phosphonium halide, in a solvent/carrier for the reactants.

Abstract: Halogenated phosphines are produced by reacting a secondary phosphine with a quaternary phosphonium halide, in a solvent/carrier for the reactants.

Abstract: A method of forming microparticles (especially including a pharmaceutically active agent) comprising incorporating an emulsifier in an aqueous liquid or in a non-aqueous solution (e.g. of dichloromethane) containing a polymer; forming a dispersion of the aqueous liquid in the non-aqueous solution; and agitating and adding a non-solvent (e.g. silicone oil) for the polymer. The presence of the emulsifier allows microparticle production over a wide range of conditions.

Abstract: A process for producing citric acid directly in the free acid form by aerobically fermenting an aqueous hydrocarbon-containing nutrient medium at a low pH with a new strain of the yeast, Candida lipolytica.