Patents by Inventor Gordon T. Rogers

Gordon T. Rogers has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for the treatment of tumors with conjugated antibody A5B7 and a prodrug
    Patent number: 5683694
    Abstract: A method for treatment of tumors to which antibody A5B7 binds is disclosed. A5B7 is a monoclonal antibody which binds to carcinoembryonic antigen. The method comprises administering to a host in need of such treatment an effective amount of a system which comprises a conjugate comprising: antibody A5B7 or a humanized version of A5B7 linked to an enzyme selected from the group consisting of carboxypeptidase G2 (CPG2), nitroreductase, a human enzyme, a non-human enzyme rendered non-immunogenic in man and a humanized catalytic antibody; and a prodrug convertible under the influence of the conjugate into a cytotoxic drug.
    Type: Grant
    Filed: June 5, 1995
    Date of Patent: November 4, 1997
    Assignee: Cancer Research Campaign Tech. Ltd. & Zeneca Ltd.
    Inventors: Kenneth D. Bagshawe, Gordon T. Rogers, Surinder K. Sharma
  • Treatment for tumors comprising conjugated antibody A5B7 and a prodrug
    Patent number: 5632990
    Abstract: A treatment for tumors to which antibody A5B7 binds is disclosed. A5B7 is a monoclonal antibody which binds to carcinoembryonic antigen. The treatment comprises administering to a host in need of such treatment an effective amount of a system which comprises: a conjugate comprising antibody A5B7 or a humanized version of A5B7 linked to an enzyme selected from the group consisting of carboxypeptidase G2 (CPG2), nitroreductase, a human enzyme, a non-human enzyme rendered non-immunogenic in man and a humanized catalytic antibody; and a prodrug convertible under the influence of the conjugate into a cytotoxic drug.
    Type: Grant
    Filed: September 28, 1994
    Date of Patent: May 27, 1997
    Assignees: Cancer Research Campaign Tech. Ltd., Zeneca Ltd.
    Inventors: Kenneth D. Bagshawe, Gordon T. Rogers, Surinder K. Sharma