Patents by Inventor Gordon Weng-Kit Cheung

Gordon Weng-Kit Cheung has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10745715
    Abstract: The present invention relates to a producer cell which expresses a tagging protein at the cell surface, such that retroviral vectors produced by the cell are tagged with the tagging protein, wherein the tagging protein comprises: i) a binding domain which binds to a capture moiety ii) a spacer; and iii) a membrane targeting domain such that, when incorporated a retroviral vector, the tagging protein facilitates purification of the retroviral vector from cellular supernatant via binding of the tagging protein to the capture moiety. The present invention also relates to a retroviral vector comprising such a producer cell-derived tagging protein.
    Type: Grant
    Filed: August 28, 2015
    Date of Patent: August 18, 2020
    Assignee: UCL BUSINESS LTD
    Inventors: Martin Pulé, Leila Mekkaoui, Gordon Weng-Kit Cheung
  • Patent number: 10704032
    Abstract: The present invention relates to a retrovirus packaging cell which expresses a temperature sensitive RNA-dependent-RNA polymerase (RdRp).
    Type: Grant
    Filed: February 24, 2017
    Date of Patent: July 7, 2020
    Assignee: UCL BUSINESS LTD
    Inventors: Martin Pulé, Leila Mekkaoui, Gordon Weng-Kit Cheung
  • Publication number: 20190055526
    Abstract: The present invention relates to a retrovirus packaging cell which expresses a temperature sensitive RNA-dependent-RNA polymerase (RdRp).
    Type: Application
    Filed: February 24, 2017
    Publication date: February 21, 2019
    Inventors: Martin Pulé, Leila Mekkaoui, Gordon Weng-Kit Cheung
  • Publication number: 20170240920
    Abstract: The present invention relates to a producer cell which expresses a tagging protein at the cell surface, such that retroviral vectors produced by the cell are tagged with the tagging protein, wherein the tagging protein comprises: i) a binding domain which binds to a capture moiety ii) a spacer; and iii) a membrane targeting domain such that, when incorporated a retroviral vector, the tagging protein facilitates purification of the retroviral vector from cellular supernatant via binding of the tagging protein to the capture moiety. The present invention also relates to a retroviral vector comprising such a producer cell-derived tagging protein.
    Type: Application
    Filed: August 28, 2015
    Publication date: August 24, 2017
    Inventors: Martin Pulé, Leila Mekkaoui, Gordon Weng-Kit Cheung