Abstract: An efficient therapeutic medicament in a powdery form for thrombosis and related diseases is prepared by the steps of: removing dirty matters on the body surface and fecal mud in the digestive tracts from live earthworms by keeping them in a slightly acidified water bath at a specified temperature; mashing the cleaned earthworms into a mushy paste; and vacuum-drying the mushy paste of the earthworms by the stepwise temperature elevation up to 70.degree. to 80.degree. C. The results of the clinical tests of the medicament are presented.

Abstract: A triterpenyl ester of organic acid other than triterpenyl esters of ferulic acid and of monobasic and dibasic saturated fatty acids. A process for producing a triterpenyl ester of organic acid other than esters of ferulic acid and of monobasic and dibasic saturated fatty acids, which comprises the reaction of a triterpenyl alcohol with an acid halide of the corresponding organic acid. A pharmaceutical composition for treatment of hyperlipidemia comprising a pharmaceutical carrier and an effective amount of a triterpenyl ester of organic acid other than triterpenyl esters of dibasic saturated fatty acids. A pharmaceutical composition for treating hyperlipidemia which comprises a pharmaceutical carrier and an effective amount of cyclobranol as an active ingredient.

Abstract: Glucopyranose-nitrosourea compounds having lower alkyl group and/or 2-chloroethyl group as substituent(s), are produced at high yield by reacting amino-glucopyranose compounds having lower alkoxy group and/or amino group(s) (or an acid-added amino group) as substituent(s), with o-nitro- or o-cyano-phenyl N-substituted-N-nitrosocarbamate compounds having lower alkyl group or 2-chloroethyl group as substituent. 1-(Lower alkyl or 2-chloroethyl)-3-(D-glucopyranos-6-yl)-1-nitrosourea compounds included within the scope of the nitrosourea compounds are novel. The nitrosourea compounds produced by this invention all show antitumor activity, among which the novel compounds exhibit excellent physical and pharmacological properties.

Abstract: Certain alkyl amino-glucopyranoside are disclosed, including alkyl N-carbamyl-N'-(2-chloroethyl)-N'-nitroso-6-amino-6-deoxy-D-glucopyranoside , alkyl N-carbamyl-N'-(2-chloroethyl)-N'-nitroso-2-amino-2-deoxy-D-glucopyranoside , and alkyl di-N,N'-[N-(2-chloroethyl)-N-nitroso-carbamyl]-2,6-di-amino-2,6-di-deoxy-D -glucopyranoside. The alkyl amino-glucopryanoside exhibits marked antitumor activity while not having diabetogenic activity and bone marrow toxicity. The alkyl amino-glucopryanoside is further water soluble and free from antibacterial activity.