Patents by Inventor Gorre Balakishan

Gorre Balakishan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pyrrolo[2,1-C][1,4]benzodiazepine linked imidazo[1,5-A]pyridine conjugates as potential antitumour agents and process for the preparation thereof
    Patent number: 8519123
    Abstract: The present invention provides a compound of general formula 7, useful as potential antitumour agents against five human cancer cell lines. The present invention further provides a process for the preparation of pyrrolo[2,1-c][1,4]benzodiazepine linked imidazo[1,5-a]pyridine conjugates attached through a piperazine moiety and different alkane spacers of general formula 7 wherein R represents H, OCH3, CF3, CN, F or Cl; n=3, 4, 5 or 6.
    Type: Grant
    Filed: March 23, 2011
    Date of Patent: August 27, 2013
    Assignee: Council of Scientific and Industrial Research
    Inventors: Ahmed Kamal, Gadupudi Ramakrishna, Paidakula Raju, Ayinampudi Venkata Subba Rao, Arutla Viswanath, Gorre Balakishan
  • C2-fluoro substituted piperazine linked pyrrolo[2,1-C][1,4] benzodiazepine dimers and a process for the preparation thereof
    Patent number: 8383618
    Abstract: The present invention provides a compounds of general formula IXa-d, useful as potential antitumour agents and pharmaceutical composition comprising these compounds exhibits binding affinity with calf thymus (CT) DNA at a molar ratio of 1:5 in aqueous sodium phosphate buffer at pH of 7.00. The present invention further provides a process for the preparation of C2-Fluoro substituted piperazine linked pyrrolo[2,1c][1-4], benzodiazepine of formula (IX).
    Type: Grant
    Filed: October 31, 2008
    Date of Patent: February 26, 2013
    Assignee: Council of Scientific & Industrial Research
    Inventors: Ahmed Kamal, Rajender, Metuku Kashireddy, Gorre Balakishan
  • PYRROLO[2,1-C][1,4]BENZODIAZEPINE LINKED IMIDAZO[1,5-A]PYRIDINE CONJUGATES AS POTENTIAL ANTITUMOUR AGENTS AND PROCESS FOR THE PREPARATION THEREOF
    Publication number: 20120253034
    Abstract: The present invention provides a compound of general formula 7, useful as potential antitumour agents against five human cancer cell lines. The present invention further provides a process for the preparation of pyrrolo[2,1-c][1,4]benzodiazepine linked imidazo[1,5-a]pyridine conjugates attached through a piperazine moiety and different alkane spacers of general formula 7 wherein R represents H, OCH3, CF3, CN, F or Cl; n=3, 4, 5 or 6.
    Type: Application
    Filed: March 23, 2011
    Publication date: October 4, 2012
    Applicant: COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH
    Inventors: Ahmed Kamal, Gadupudi Ramakrishna, Paidakula Raju, Ayinampudi Venkata Subba Rao, Arutla Viswanath, Gorre Balakishan
  • C2-FLUORO SUBSTITUTED PIPERAZINE LINKED PYRROLO[2,1-C][1,4] BENZODIAZEPINE DIMERS AND A PROCESS FOR THE PREPARATION THEREOF
    Publication number: 20110190275
    Abstract: The present invention provides a compounds of general formula IXa-d, useful as potential antitumour agents and pharmaceutical composition comprising these compounds exhibits binding affinity with calf thymus (CT) DNA at a molar ratio of 1:5 in aqueous sodium phosphate buffer at pH of 7.00. The present invention further provides a process for the preparation of C2-Fluoro substituted piperazine linked pyrrolo[2,1c][1-4], benzodiazepine of formula (IX).
    Type: Application
    Filed: October 31, 2008
    Publication date: August 4, 2011
    Inventors: Ahmed Kamal, Rajender, Metuku Kashireddy, Gorre Balakishan