Patents by Inventor Gosse Adema

Gosse Adema has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pharmaceutical Compositions Comprising a GPG Oligodeoxynucleotide and Cyclic Di-GMP
    Publication number: 20160136197
    Abstract: The present invention relates to pharmaceutical compositions comprising an immunostimulatory amount of at least two immunopotentiators, wherein a first immunopotentiator is a non-methylated cytidyl guanosyl oligodeoxynucleotide (CpG ODN) and a second immunopotentiator is 3?,5?-cyclic diguanylic acid (c-di-GMP), and a pharmaceutically acceptable carrier. The invention also relates to the use of such pharmaceutical compositions for the induction of an immune response against tumor-specific antigens. Also the invention relates to their use in in situ tumor-destruction therapy and to such pharmaceutical compositions for use in the treatment of a mammal suffering from cancer.
    Type: Application
    Filed: June 13, 2014
    Publication date: May 19, 2016
    Inventors: Carla Christina Schrier, Martijn BROK DEN, Gosse Adema
  • IMMUNOSTIMULATING SAPONINS FOR USE IN SITU TUMOR-DESTRUCTION THERAPY
    Publication number: 20110256167
    Abstract: The present invention relates to pharmaceutical compositions for use in in situ tumor-destruction therapy comprising the steps of tumor destruction and administration of an immunostimulating amount of an immunopotentiator, and to the use of such pharmaceutical compositions in the manufacture of a medicament.
    Type: Application
    Filed: December 22, 2009
    Publication date: October 20, 2011
    Inventors: Carla Christina Schrier, Stefan Nierkens, Gosse Adema, Martijn Den Brok, Theodoor Jaques Marie Ruers
  • Antibodies that specifically bind to FDF03
    Publication number: 20050287582
    Abstract: Nucleic acids encoding various monocyte cell proteins from a primate, reagents related thereto, including specific antibodies, and purified proteins are described. Methods of using said reagents and related diagnostic kits are also provided.
    Type: Application
    Filed: August 4, 2005
    Publication date: December 29, 2005
    Applicant: Schering Corporation
    Inventors: Gosse Adema, Linde Meyaard, Daniel Gorman, Terrill McClanahan, Sandra Zurawski, Gerard Zurawski, Lewis Lanier, Joseph Phillips
  • Mammalian genes; related reagents and methods
    Publication number: 20050142587
    Abstract: Purified genes encoding proteins from a mammal, reagents related thereto including purified proteins, specific antibodies, and nucleic acids encoding these molecules are provided. Methods of using said reagents and diagnostic kits are also provided.
    Type: Application
    Filed: October 6, 2004
    Publication date: June 30, 2005
    Applicant: Schering Corporation
    Inventors: Constance Zlot, Gosse Adema, Carl Figdor, Joseph Phillips
  • Isolated mammalian monocyte cell genes; related reagents
    Publication number: 20050059808
    Abstract: Nucleic acids encoding various monocyte cell proteins from a primate, reagents related thereto, including specific antibodies, and purified proteins are described. Methods of using said reagents and related diagnostic kits are also provided.
    Type: Application
    Filed: February 11, 2004
    Publication date: March 17, 2005
    Inventors: Gosse Adema, Linde Meyaard, Daniel Gorman, Terrill McClanahan, Sandra Zurawski, Gerard Zurawski, Lewis Lanier, Joseph Phillips