Patents by Inventor Gossett Augustus Campbell
Gossett Augustus Campbell has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10596263Abstract: A granulation formulation of 5-[[4-[(2,3-dimethyl-2H-indazol-6-yl)methylamino]-2-pyrimidinyl]amino]-2-methylbenzenesulfonamide or pharmaceutically acceptable salt thereof, which is adapted for reconstitution with an aqueous vehicle, and associated oral suspension.Type: GrantFiled: August 22, 2018Date of Patent: March 24, 2020Assignee: Novartis AGInventors: Gossett Augustus Campbell, Helen Richardson, Peter A. Williams
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Publication number: 20190389870Abstract: The present invention relates to a salt form of a benzodiazepine derivative, in particular crystalline solid state forms, to pharmaceutical compositions comprising the same and to its use in therapy.Type: ApplicationFiled: September 5, 2019Publication date: December 26, 2019Inventors: Gossett Augustus CAMPBELL, Asa Elisabeth GLADWIN
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Patent number: 10450319Abstract: The present invention relates to a salt form of a benzodiazepine derivative, in particular crystalline solid state forms, to pharmaceutical compositions comprising the same and to its use in therapy.Type: GrantFiled: April 18, 2018Date of Patent: October 22, 2019Assignee: GlaxoSmithKline Intellectual Property (No.2) LimitedInventors: Gossett Augustus Campbell, Asa Elisabeth Gladwin
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Publication number: 20180360971Abstract: A granulation formulation of 5-[[4-[(2,3-dimethyl-2H-indazol-6-yl)methylamino]-2-pyrimidinyl]amino]-2-methylbenzenesulfonamide or pharmaceutically acceptable salt thereof, which is adapted for reconstitution with an aqueous vehicle, and associated oral suspension.Type: ApplicationFiled: August 22, 2018Publication date: December 20, 2018Inventors: Gossett Augustus Campbell, Helen Richardson, Peter A. Williams
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Publication number: 20180305365Abstract: The present invention relates to a salt form of a benzodiazepine derivative, in particular crystalline solid state forms, to pharmaceutical compositions comprising the same and to its use in therapy.Type: ApplicationFiled: April 18, 2018Publication date: October 25, 2018Inventors: Gossett Augustus CAMPBELL, Asa Elisabeth Gladwin
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Patent number: 10080802Abstract: A granulation formulation of 5-[[4-[(2,3-dimethyl-2H-indazol-6-yl)methylamino]-2-pyrimidinyl]amino]-2-methylbenzenesulfonamide or pharmaceutically acceptable salt thereof, which is adapted for reconstitution with an aqueous vehicle, and associated oral suspension.Type: GrantFiled: January 13, 2016Date of Patent: September 25, 2018Assignee: Novartis AGInventors: Gossett Augustus Campbell, Helen Richardson, Peter A. Williams
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Patent number: 9975901Abstract: The present invention relates to a salt form of a benzodiazepine derivative, in particular crystalline solid state forms, to pharmaceutical compositions comprising the same and to its use in therapy.Type: GrantFiled: September 30, 2015Date of Patent: May 22, 2018Assignee: GlaxoSmithKline Intellectual Property (No. 2) LimitedInventors: Gossett Augustus Campbell, Asa Elisabeth Gladwin
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Publication number: 20170298071Abstract: The present invention relates to a salt form of a benzodiazepine derivative, in particular crystalline solid state forms, to pharmaceutical compositions comprising the same and to its use in therapy.Type: ApplicationFiled: September 30, 2015Publication date: October 19, 2017Inventors: Gossett Augustus CAMPBELL, Asa Elisabeth GLADWIN
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Publication number: 20160120988Abstract: A granulation formulation of 5-[[4-[(2,3-dimethyl-2H-indazol-6-yl)methylamino]-2-pyrimidinyl]amino]-2-methylbenzenesulfonamide or pharmaceutically acceptable salt thereof, which is adapted for reconstitution with an aqueous vehicle, and associated oral suspension.Type: ApplicationFiled: January 13, 2016Publication date: May 5, 2016Inventors: Gossett Augustus Campbell, Helen Richardson, Peter A. Williams
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Patent number: 9278099Abstract: A granulation formulation of 5-[[4-[(2,3-dimethyl-2H-indazol-6-yl)methylamino]-2-pyrimidinyl]amino]-2-methylbenzenesulfonamide or pharmaceutically acceptable salt thereof, which is adapted for reconstitution with an aqueous vehicle, and associated oral suspension.Type: GrantFiled: October 16, 2012Date of Patent: March 8, 2016Assignee: Novartis AGInventors: Gossett Augustus Campbell, Helen Richardson, Peter A. Williams
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Patent number: 8999640Abstract: Detection of miniscule amounts of nucleic acid is accomplished via binding of target nucleic acid to probe material, composed of nucleic acid, which is bound to a sensor configured to sense mass. The sensor is prepared by immobilizing a probe material to a surface of the sensor, wherein the probe material is known to bind to the target nucleic acid. The prepared sensor is exposed to the target nucleic acid. The target nucleic acid binds to the probe material. The mass accumulated on the sensor reflects the amount of target nucleic acid bound to the probe material.Type: GrantFiled: July 31, 2013Date of Patent: April 7, 2015Assignee: Drexel UniversityInventors: Rajakkannu Mutharasan, Kishan Rijal, David R. Maraldo, Gossett Augustus Campbell
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Publication number: 20140255505Abstract: A granulation formulation of 5-[[4-[(2,3-dimethyl-2H-indazol-6-yl)methylamino]-2-pyrimidinyl]amino]-2-methylbenzenesulfonamide or pharmaceutically acceptable salt thereof, which is adapted for reconstitution with an aqueous vehicle, and associated oral suspension.Type: ApplicationFiled: October 16, 2012Publication date: September 11, 2014Inventors: Gossett Augustus Campbell, Helen Richardson, Peter A. Williams
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Patent number: 8778446Abstract: Flow cells configured for piezoelectric millimeter-sized cantilever sensors provide direct, sensitive detection of analytes in fluid media. The flow cells comprise a flow inlet and a flow outlet positioned to cause sample flow past a sensing surface of the cantilever sensor. The flow cell is configured for millimeter-sized cantilever sensors. The geometry of the flow cell influences the sample flow and thus the interaction of the flow with the cantilever sensor.Type: GrantFiled: August 9, 2007Date of Patent: July 15, 2014Assignee: Drexel UniversityInventors: Rajakkannu Mutharasan, Gossett Augustus Campbell
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Publication number: 20140045178Abstract: Detection of miniscule amounts of nucleic acid is accomplished via binding of target nucleic acid to probe material, composed of nucleic acid, which is bound to a sensor configured to sense mass. The sensor is prepared by immobilizing a probe material to a surface of the sensor, wherein the probe material is known to bind to the target nucleic acid. The prepared sensor is exposed to the target nucleic acid. The target nucleic acid binds to the probe material. The mass accumulated on the sensor reflects the amount of target nucleic acid bound to the probe material.Type: ApplicationFiled: July 31, 2013Publication date: February 13, 2014Applicant: Drexel UniversityInventors: Rajakkannu Mutharasan, Kishan Rijal, David R. Maraldo, Gossett Augustus Campbell
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Patent number: 8512947Abstract: Detection of miniscule amounts of nucleic acid is accomplished via binding of target nucleic acid to probe material, composed of nucleic acid, which is bound to a sensor configured to sense mass. The sensor is prepared by immobilizing a probe material to a surface of the sensor, wherein the probe material is known to bind to the target nucleic acid. The prepared sensor is exposed to the target nucleic acid. The target nucleic acid binds to the probe material. The mass accumulated on the sensor reflects the amount of target nucleic acid bound to the probe material.Type: GrantFiled: June 18, 2008Date of Patent: August 20, 2013Assignee: Drexel UniversityInventors: Rajakkannu Mutharasan, Kishan Rijal, David R. Maraldo, Gossett Augustus Campbell
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Patent number: 8511163Abstract: A piezoelectric cantilever sensor includes a piezoelectric layer and a non-piezoelectric layer, a portion of which is attached to the piezoelectric layer. In one embodiment, one end of the non-piezoelectric layer extends beyond the end of piezoelectric layer to provide an overhang. The overhang piezoelectric cantilever sensor enables increased sensitivity allowing application of the device in more viscous environments, such as liquid media, as well as application in liquid media at higher flow rates than conventional piezoelectric cantilevers. In another embodiment, the sensor includes first and second bases and at least one of the piezoelectric layer and the non-piezoelectric layer is affixed to each of the first and second bases to form the piezoelectric cantilever sensor. In this embodiment, the sensor is robust and exhibits excellent sensing characteristics in both gaseous and liquid media, even when subjected to relatively high flow rates.Type: GrantFiled: February 25, 2011Date of Patent: August 20, 2013Assignee: Drexel UniversityInventors: Rajakkannu Mutharasan, David Maraldo, Gossett Augustus Campbell, Kishan Rijal
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Patent number: 8474319Abstract: A piezoelectric cantilever sensor includes a piezoelectric layer and a non-piezoelectric layer, a portion of which is attached to the piezoelectric layer. In one embodiment, one end of the non-piezoelectric layer extends beyond the end of piezoelectric layer to provide an overhang. The overhang piezoelectric cantilever sensor enables increased sensitivity allowing application of the device in more viscous environments, such as liquid media, as well as application in liquid media at higher flow rates than conventional piezoelectric cantilevers. In another embodiment, the sensor includes first and second bases and at least one of the piezoelectric layer and the non-piezoelectric layer is affixed to each of the first and second bases to form the piezoelectric cantilever sensor. In this embodiment, the sensor is robust and exhibits excellent sensing characteristics in both gaseous and liquid media, even when subjected to relatively high flow rates.Type: GrantFiled: February 25, 2011Date of Patent: July 2, 2013Assignee: Drexel UniversityInventors: Rajakkannu Mutharasan, David Maraldo, Gossett Augustus Campbell, Kishan Rijal
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Patent number: 8171795Abstract: A method for detection of airborne biological agent using a piezoelectric cantilever sensor that includes a piezoelectric layer and a non-piezoelectric layer. A recognition entity is placed on one or both of the two layers. The antibody that recognizes and binds to the airborne species may be chemically immobilized on the cantilever sensor surface. In one embodiment, the cantilever sensor is attached to a base at only one end. In another embodiment, the sensor includes first and second bases and at least one of the piezoelectric layer and the non-piezoelectric layer is affixed to each of the first and second bases to form a piezoelectric cantilever beam sensor. In this embodiment, resonance is measured via stress on the piezoelectric layer and it has been demonstrated that such sensors are robust and exhibit excellent sensing characteristics in gaseous media with sufficient sensitivity to detect airborne species at relatively low concentrations.Type: GrantFiled: May 10, 2007Date of Patent: May 8, 2012Assignee: Drexel UniversityInventors: Rajakkannu Mutharasan, David L. deLesdernier, Gossett Augustus Campbell, David R. Maraldo, Peter A. Nagy
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Publication number: 20120094270Abstract: A method for detection of airborne biological agent using a piezoelectric cantilever sensor that includes a piezoelectric layer and a non-piezoelectric layer. A recognition entity is placed on one or both of the two layers. The antibody that recognizes and binds to the airborne species may be chemically immobilized on the cantilever sensor surface. In one embodiment, the cantilever sensor is attached to a base at only one end. In another embodiment, the sensor includes first and second bases and at least one of the piezoelectric layer and the non-piezoelectric layer is affixed to each of the first and second bases to form a piezoelectric cantilever beam sensor. In this embodiment, resonance is measured via stress on the piezoelectric layer and it has been demonstrated that such sensors are robust and exhibit excellent sensing characteristics in gaseous media with sufficient sensitivity to detect airborne species at relatively low concentrations.Type: ApplicationFiled: May 10, 2007Publication date: April 19, 2012Inventors: Rajakkannu Mutharasan, David L. de Lesdernier, Gossett Augustus Campbell, David R. Maraldo, Peter A. Nagy
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Publication number: 20110138915Abstract: A piezoelectric cantilever sensor includes a piezoelectric layer and a non-piezoelectric layer, a portion of which is attached to the piezoelectric layer. In one embodiment, one end of the non-piezoelectric layer extends beyond the end of piezoelectric layer to provide an overhang. The overhang piezoelectric cantilever sensor enables increased sensitivity allowing application of the device in more viscous environments, such as liquid media, as well as application in liquid media at higher flow rates than conventional piezoelectric cantilevers. In another embodiment, the sensor includes first and second bases and at least one of the piezoelectric layer and the non-piezoelectric layer is affixed to each of the first and second bases to form the piezoelectric cantilever sensor. In this embodiment, the sensor is robust and exhibits excellent sensing characteristics in both gaseous and liquid media, even when subjected to relatively high flow rates.Type: ApplicationFiled: February 25, 2011Publication date: June 16, 2011Applicant: DREXEL UNIVERSITYInventors: Rajakkannu Mutharasan, David Maraldo, Gossett Augustus Campbell, Kishan Rijal