Patents by Inventor Government of the United States of America as Represented by the Secretary of the Department of Veteran

Government of the United States of America as Represented by the Secretary of the Department of Veteran has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Expansion of Interferon-Gamma-Producing T-Cells Using Glypican-3 Peptide Library
    Publication number: 20130217122
    Abstract: The present invention encompasses a method for expanding an antigen specific T cell from a population of cells. The method of the present invention comprises contacting a population of cells with an MHC restricted antigenic glypican-3 peptide. In some instances, the T cell is expanded using monocyte-derived dendritic cells and defined MHC restricted antigenic glypican-3 peptides. In one embodiment, high-affinity antigen-specific T-cell receptors (TCRs) can be cloned from the antigen specific T cell.
    Type: Application
    Filed: February 21, 2013
    Publication date: August 22, 2013
    Applicants: The Trustees of the University of Pennsylvania, Veteran
    Inventors: The Trustees of the University of Pennsylvania, Government of the United States of America as Represented by the Secretary of the Department of Veteran