Abstract: A device may (i) at least one electrode associated with an electric generator to generate a pulsed electric field (PEF) in solid tissue, wherein said electrode comprises more than one hole/opening at the end in contact with said solid tissue and an insulating sleeve that can be adjusted to alter the side hole profile. A device may (ii) a cellular-component extraction element by suction through at least one electrode, wherein upon introducing said at least one electrode into said solid tissue, and generating the PEF, the PEF induces a biophysical response from cells in solid tissue or other condition (such as be blood, in vitro etc.) resulting in at least one cellular component to exit to extracellular matrix which is then extracted by said extraction element.

Abstract: Systems, methods and computer-accessible mediums can be provided that can establish particular parameters for electric pulses based on a characteristic(s) of the tissue(s), and control an application of the electric pulses to tissue(s) for a plurality of automatically controlled and separated time periods to ablate the tissue(s) through mediation of membrane potential and through inducing the cells through a plurality of charge-discharge cycles such that an electroporation of a majority of the tissue(s) is prevented or reduced.

Abstract: An exemplary apparatus, can include, for example, a circulating tumor cell (CTC) treatment arrangement, a pump arrangement configured to circulate a fluid through the CTC treatment arrangement, and an electric field generator electrically connected to the CTC treatment arrangement, and configured to apply an electric field to the fluid circulating through the CTC treatment arrangement. The pump arrangement can be a peristaltic pump, which can be configured to continuously circulate the fluid through the CTC treatment arrangement. According to another exemplary embodiment of the present disclosure, method, system and computer-accessible medium can be provided for killing at least one circulating tumor cell (CTC). Using such exemplary embodiment, blood can be pumped from a body of a patient to an electroporation chamber inside of a CTC treatment arrangement. An electric field can be applied to the blood located in the electroporation chamber in order to kill the CTC.

Abstract: Exemplary embodiments of the present disclosure can include for example, an apparatus, which can include a manipulating arrangement configured to cause a medical device to move, where a portion of the manipulating arrangement can be partly composed of a non-magnetic material, and a computer arrangement in a communication with the manipulating arrangement, and configured to remotely operate the manipulating arrangement. The computer arrangement can include a computer. The communication can be a wired or wireless communication. The medical device can include (i) a catheter, (ii) an endoscope, or (iii) a needle. The manipulating arrangement can include a catheter as the medical device that can be attached to a manipulator.

Abstract: Systems, methods and computer-accessible mediums can be provided that can establish particular parameters for electric pulses based on a characteristic(s) of the tissue(s), and control an application of the electric pulses to tissue(s) for a plurality of automatically controlled and separated time periods to ablate the tissue(s) through mediation of membrane potential and through inducing the cells through a plurality of charge-discharge cycles such that an electroporation of a majority of the tissue(s) is prevented or reduced.

Abstract: An exemplary apparatus, can include, for example, a circulating tumor cell (CTC) treatment arrangement, a pump arrangement configured to circulate a fluid through the CTC treatment arrangement, and an electric field generator electrically connected to the CTC treatment arrangement, and configured to apply an electric field to the fluid circulating through the CTC treatment arrangement. The pump arrangement can be a peristaltic pump, which can be configured to continuously circulate the fluid through the CTC treatment arrangement. According to another exemplary embodiment of the present disclosure, method, system and computer-accessible medium can be provided for killing at least one circulating tumor cell (CTC). Using such exemplary embodiment, blood can be pumped from a body of a patient to an electroporation chamber inside of a CTC treatment arrangement. An electric field can be applied to the blood located in the electroporation chamber in order to kill the CTC.

Abstract: Systems, methods and computer-accessible mediums can be provided that can establish particular parameters for electric pulses based on a characteristic(s) of the tissue(s), and control an application of the electric pulses to tissue(s) for a plurality of automatically controlled and separated time periods to ablate the tissue(s) through mediation of membrane potential and through inducing the cells through a plurality of charge-discharge cycles such that an electroporation of a majority of the tissue(s) is prevented or reduced.

Abstract: Exemplary embodiments of the present disclosure can include for example, an apparatus, which can include a manipulating arrangement configured to cause a medical device to move, where a portion of the manipulating arrangement can be partly composed of a non-magnetic material, and a computer arrangement in a communication with the manipulating arrangement, and configured to remotely operate the manipulating arrangement. The computer arrangement can include a computer. The communication can be a wired or wireless communication. The medical device can include (i) a catheter, (ii) an endoscope, or (iii) a needle. The manipulating arrangement can include a catheter as the medical device that can be attached to a manipulator.

Abstract: Systems, methods and computer-accessible mediums can be provided that can establish particular parameters for electric pulses based on a characteristic(s) of the tissue(s), and control an application of the electric pulses to tissue(s) for a plurality of automatically controlled and separated time periods to ablate the tissue(s) through mediation of membrane potential and through inducing the cells through a plurality of charge—discharge cycles such that an electroporation of a majority of the tissue(s) is prevented or reduced.

Abstract: A system for manipulating elongate surgical instruments comprises a console, which comprises an input controller. The input controller may have a haptic feedback mechanism. The system further comprises a slave component, which comprises a first linear actuator, a second linear actuator, and a first rotational actuator. Each actuator is in electrical communication with the input controller. The slave component further comprises a force sensor in electronic communication with the input controller. The force sensor is configured to measure a force acting upon the first elongate member on at least one degree of freedom. The force sensor will send a force signal to the haptic feedback mechanism of the input controller.

Abstract: The present invention may be embodied as a method of minimally-invasive surgery (“MIS”) training wherein a simulator having a display, a computer, and a first input device, is provided. A video of an MIS is displayed on the display, and a first surgical tool is visible in at least a portion of the video. A match zone corresponding to a position on the first surgical tool is determined. A computer-generated virtual surgical tool (“CG tool”) is superimposed on the displayed video. The CG tool is selectively controlled by the first input device. A target position of the CG tool is determined. If the target position is not determined to be within the match zone, further steps may be taken. For example, the video may be paused, a message may be displayed to the operator, or the computer may signal the input device to move to a position such that the target position is within the match zone.

Abstract: A system according to the invention may include a frame, a computer, a display, and two input devices. The frame may be adjustable, may be made from a lightweight material, and may fold for easier portability. The display and the computer may be in communication with each other and each may be attached to the frame. The display may be a binocular display, or may be a touchscreen display. Additional displays may be used. Two input devices may be used to simulate the master console of a surgical robot. The input devices may be articulated armature devices suitable for providing 3D input. The input devices may be attached to the frame in an “upside-down” configuration wherein a base of each input device is affixed to the frame such that a first joint of an arm is below the base. The input devices may be in communication with the computer and may provide positional signals to the computer. The positional signals may correspond to a position of an arm of each input device.