Patents by Inventor Grégory Louis Joseph Bar

Grégory Louis Joseph Bar has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Fused pyrazine compounds useful for the treatment of degenerative and inflammatory diseases
    Patent number: 9006237
    Abstract: Novel fused pyrazine compounds are disclosed that have a formula represented by the following: The compounds may be prepared as pharmaceutical compositions, and may be used for the prevention and treatment of a variety of conditions in mammals including humans, including by way of non-limiting example, inflammation, rheumatoid arthritis and others.
    Type: Grant
    Filed: March 2, 2012
    Date of Patent: April 14, 2015
    Assignee: Janssen Pharmaceutica NV
    Inventors: Martin James Inglis Andrews, Mark Stuart Chambers, Wolfgang Schmidt, Giovanni Alessandro Tricarico, Grégory Louis Joseph Bar, Kim Louise Hirst, Olga Raquel Pinto Santos Oliveira Roussel, Juha Andrew Clase
  • Fused Pyrazine Compounds Useful for the Treatment of Degenerative and Inflammatory Diseases
    Publication number: 20120232075
    Abstract: Novel fused pyrazine compounds are disclosed that have a formula represented by the following: The compounds may be prepared as pharmaceutical compositions, and may be used for the prevention and treatment of a variety of conditions in mammals including humans, including by way of non-limiting example, inflammation, rheumatoid arthritis and others.
    Type: Application
    Filed: March 2, 2012
    Publication date: September 13, 2012
    Inventors: Martin James Inglis Andrews, Mark Stuart Chambers, Wolfgang Schmidt, Giovanni Alessandro Tricarico, Grégory Louis Joseph Bar, Kim Louise Hirst, Olga Raquel Pinto Santos Oliveira Roussel, Juha Andrew Clase
  • Fused pyrazine compounds useful for the treatment of degenerative and inflammatory diseases
    Patent number: 8148369
    Abstract: Novel fused pyrazine compounds are disclosed that have a formula represented by the following: The compounds may be prepared as pharmaceutical compositions, and may be used for the prevention and treatment of a variety of conditions in mammals including humans, including by way of non-limiting example, inflammation, rheumatoid arthritis and others.
    Type: Grant
    Filed: May 7, 2008
    Date of Patent: April 3, 2012
    Assignee: Janssen Pharmaceutica NV
    Inventors: Martin James Inglis Andrews, Mark Stuart Chambers, Wolfgang Schmidt, Giovanni Alessandro Tricarico, Grégory Louis Joseph Bar, Kim Louise Hirst, Olga Raquel Pinto Santos Oliveira Roussel, Juha Andrew Clase
  • Fused pyrazine compounds useful for the treatment of degenerative and inflammatory diseases
    Patent number: 8138193
    Abstract: Novel fused pyrazine compounds are disclosed that have a formula represented by the following: with Z, R1, R2, R8 and R9 as defined in the written description. The compounds may be prepared as pharmaceutical compositions, and may be used for the prevention and treatment of a variety of conditions in mammals including humans, including by way of non-limiting example, inflammation, rheumatoid arthritis and others.
    Type: Grant
    Filed: April 2, 2010
    Date of Patent: March 20, 2012
    Assignee: Janssen Pharmaceutica N.V.
    Inventors: Martin James Inglis Andrews, Mark Stuart Chambers, Wolfgang Schmidt, Grégory Louis Joseph Bar
  • Fused pyrazine compounds useful for the treatment of degenerative and inflammatory diseases
    Patent number: 8133895
    Abstract: Novel fused pyrazine compounds are disclosed that have a formula represented by the following: The compounds may be prepared as pharmaceutical compositions, and may be used for the prevention and treatment of a variety of conditions in mammals including humans, including by way of non-limiting example, inflammation, rheumatoid arthritis and others.
    Type: Grant
    Filed: May 7, 2008
    Date of Patent: March 13, 2012
    Assignee: Janssen Pharmaceutica N.V.
    Inventors: Martin James Inglis Andrews, Mark Stuart Chambers, Wolfgang Schmidt, Grégory Louis Joseph Bar
  • IMIDAZOLOPYRIDINE COMPOUNDS USEFUL FOR THE TREATMENT OF DEGENERATIVE AND INFLAMMATORY DISEASES
    Publication number: 20120010206
    Abstract: Novel imidazolopyridine compounds are disclosed that have a formula represented by the following: The compounds may be prepared as pharmaceutical compositions, and may be used for the prevention and treatment of a variety of conditions in mammals including humans, including by way of non-limiting example, ECM degradation, joint degradation and/or inflammation, and others.
    Type: Application
    Filed: May 25, 2011
    Publication date: January 12, 2012
    Inventors: Paul John EDWARDS, Sébastien Laurent Xavier MARTINA, Martin James Inglis ANDREWS, Grégory Louis Joseph BAR, Brigitte ALLART, Andrew BURRITT, Xueliang TAO, Friedrich Erich Karl KROLL
  • Substituted triazolopyrazines useful for the treatment of degenerative and inflammatory diseases
    Patent number: 8012983
    Abstract: Novel [1.2.4]triazolo[1,5-a]pyrazine and imidazo[1,2-a]pyrazine compounds are disclosed that have a formula represented by the following: The compounds may be prepared as pharmaceutical compositions, and may be used for the prevention and treatment of a variety of conditions in mammals including humans, including by way of non-limiting example, pain, inflammation, and others.
    Type: Grant
    Filed: May 6, 2009
    Date of Patent: September 6, 2011
    Assignee: Galapagos NV
    Inventors: Martin James Inglis Andrews, Mark Stuart Chambers, Hervé Van De Poël, Grégory Louis Joseph Bar
  • Imidazolopyridine compounds useful for the treatment of degenerative and inflammatory diseases
    Patent number: 7951818
    Abstract: Novel imidazolopyridine compounds are disclosed that have a formula represented by the following: The compounds may be prepared as pharmaceutical compositions, and may be used for the prevention and treatment of a variety of conditions in mammals including humans, including by way of non-limiting example, ECM degradation, joint degradation and/or inflammation, and others.
    Type: Grant
    Filed: November 30, 2007
    Date of Patent: May 31, 2011
    Assignee: Galapagos NV
    Inventors: Paul John Edwards, Sébastien Laurent Xavier Martina, Martin James Inglis Andrews, Grégory Louis Joseph Bar, Brigitte Allart, Andrew Burritt, Xueliang Tao, Friedrich Erich Karl Kroll
  • FUSED PYRAZINE COMPOUNDS USEFUL FOR THE TREATMENT OF DEGENERATIVE AND INFLAMMATORY DISEASES
    Publication number: 20100240666
    Abstract: Novel fused pyrazine compounds are disclosed that have a formula represented by the following: with Z, R1, R2, R8 and R9 as defined in the written description. The compounds may be prepared as pharmaceutical compositions, and may be used for the prevention and treatment of a variety of conditions in mammals including humans, including by way of non-limiting example, inflammation, rheumatoid arthritis and others.
    Type: Application
    Filed: April 2, 2010
    Publication date: September 23, 2010
    Inventors: Martin James Inglis ANDREWS, Mark Stuart Chambers, Wolfgang Schmidt, Grégory Louis Joseph Bar
  • FUSED PYRAZINE COMPOUNDS USEFUL FOR THE TREATMENT OF DEGENERATIVE AND INFLAMMATORY DISEASES
    Publication number: 20090286798
    Abstract: Novel[1.2.4]triazolo[1,5-a]pyrazine and imidazo[1,2-a]pyrazine compounds are disclosed that have a formula represented by the following: The compounds may be prepared as pharmaceutical compositions, and may be used for the prevention and treatment of a variety of conditions in mammals including humans, including by way of non-limiting example, pain, inflammation, and others.
    Type: Application
    Filed: May 6, 2009
    Publication date: November 19, 2009
    Inventors: Martin James Inglis Andrews, Mark Stuart Chambers, Hervé Van De Poël, Grégory Louis Joseph Bar
  • Fused pyrazine compounds useful for the treatment of degenerative and inflmmatory diseases
    Publication number: 20090131446
    Abstract: Novel fused pyrazine compounds are disclosed that have a formula represented by the following: The compounds may be prepared as pharmaceutical compositions, and may be used for the prevention and treatment of a variety of conditions in mammals including humans, including by way of non-limiting example, inflammation, rheumatoid arthritis and others.
    Type: Application
    Filed: May 7, 2008
    Publication date: May 21, 2009
    Inventors: Martin James Inglis Andrews, Mark Stuart Chambers, Wolfgang Schmidt, Gregory Louis Joseph Bar
  • Imidazolopyridine compounds useful for the treatment of degenerative and inflammatory diseases
    Publication number: 20090048245
    Abstract: Novel imidazolopyridine compounds are disclosed that have a formula represented by the following: The compounds may be prepared as pharmaceutical compositions, and may be used for the prevention and treatment of a variety of conditions in mammals including humans, including by way of non-limiting example, ECM degradation, joint degradation and/or inflammation, and others.
    Type: Application
    Filed: November 30, 2007
    Publication date: February 19, 2009
    Inventors: Paul John Edwards, Sebastien Laurent Xavier Martina, Martin James Inglis Andrews, Gregory Louis Joseph Bar, Brigitte Allart, Andrew Burritt, Xueliang Tao, Friedrich Erich Karl Kroll
  • Fused pyrazine compounds useful for the treatment of degenerative and inflammatory diseases
    Publication number: 20090012078
    Abstract: Novel fused pyrazine compounds are disclosed that have a formula represented by the following: The compounds may be prepared as pharmaceutical compositions, and may be used for the prevention and treatment of a variety of conditions in mammals including humans, including by way of non-limiting example, inflammation, rheumatoid arthritis and others.
    Type: Application
    Filed: May 7, 2008
    Publication date: January 8, 2009
    Inventors: Martin James Inglis Andrews, Mark Stuart Chambers, Wolfgang Schmidt, Giovanni Alessandro Tricarico, Gregory Louis Joseph Bar, Kim Louise Hirst, Olga Raquel Pinto Santos Oliveira Roussel, Juha Andrew Clase