Abstract: Provided is an audio therapy system designed for use with incubated infants. The system includes an audio playback device configured to store and play back recordings of soothing music, a mother's heartbeat, a mother's voice, or nature sounds. This audio playback device electrically and operatively couples to one or more speaker units, which are removably secured to the interior of an incubation unit. In this manner, audio playback from the audio is played within the interior of an incubation unit to calm and soothe an infant contained therein. The audio playback device is stored within a cradle that removably secures to the exterior of an incubation unit, to reduce the likelihood that audio therapy will be abruptly initiated or discontinued.