Patents by Inventor Graciela Pavon-Djavid

Graciela Pavon-Djavid has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Biomimetic prosthetic ligament and production method thereof
    Patent number: 7700147
    Abstract: Biomimetic artificial prostheses which are made from polyester, such as polyethylene terephthalate, and a method for the biomimetic functionalization of such prostheses. The method includes a step involving the grafting of biologically-active polymers or copolymers to the polyester surface of the prostheses, the grafting step consisting of the peroxidation of the surface by ozonation followed by a step including the radical polymerization of a solution of at least one monomer. The method also includes an optional step consisting in impregnating the prostheses with type I and/or II collagen and/or fibronectins. The prostheses thus obtained enable a normal and uniform regrowth of the fibroblasts, thereby significantly improving the biological integration of such polyester prostheses.
    Type: Grant
    Filed: January 19, 2004
    Date of Patent: April 20, 2010
    Assignee: LARS- Laboratoire d'Application et de Recherche Scientifique
    Inventors: Bernard Brulez, Jacques-Philippe Laboureau, Veronique Migonney, Mihaela Ciobanu, Graciela Pavon-Djavid, Alain Siove
  • Biomimetic prosthetic ligament and production method thereof
    Publication number: 20060136057
    Abstract: Biomimetic artificial prostheses which are made from polyester, such as polyethylene terephthalate, and a method for the biomimetic functionalization of such prostheses. The method includes a step involving the grafting of biologically-active polymers or copolymers to the polyester surface of the prostheses, the grafting step consisting of the peroxidation of the surface by ozonation followed by a step including the radical polymerization of a solution of at least one monomer. The method also includes an optional step consisting in impregnating the prostheses with type I and/or II collagen and/or fibronectins. The prostheses thus obtained enable a normal and uniform regrowth of the fibroblasts, thereby significantly improving the biological integration of such polyester prostheses.
    Type: Application
    Filed: January 19, 2004
    Publication date: June 22, 2006
    Applicant: LARS LABORATOIRE D'APPLICATION ET DE RECHERCHE SCI
    Inventors: Bernard Brulez, Jacques-Philippe Laboreau, Veronique Migonney, Mihaela Ciobanu, Graciela Pavon-Djavid, Alain Siove