Patents by Inventor Graeme I. Sevenson

Graeme I. Sevenson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Dioxo-tetrahydroquinoline derivatives
    Patent number: 5268378
    Abstract: A class of 2,4-dioxo-1,2,3,4-tetrahydroquinoline derivatives, substituted at the 3-position by a range of carbonyl-containing substituents or by a five- or six-membered heteroaromatic moiety, are selective non-competitive antagonists of NMDA receptors and/or are antagonists of AMPA receptors, and are therefore of utility in the treatment of conditions, such as neurodegenerative disorders, convulsions or schizophrenia, which require the administration of an NMDA and/or AMPA antagonist.
    Type: Grant
    Filed: January 22, 1992
    Date of Patent: December 7, 1993
    Assignee: Merck Sharp & Dohme, Limited
    Inventors: Raymond Baker, Paul D. Leeson, Michael Rowley, Graeme I. Sevenson