Abstract: A processing device has a plurality of interfaces and a plurality of processors. During different phases of execution of a computer program, different processors are associated with different interfaces, such that the connectivity between processors and interfaces for the sending of egress data and the receiving of ingress data may change during execution of that computer program. The change in this connectivity is directed by the compiled code running on the processors. The compiled code selects which buses associated with which interfaces, given processors are to connect to for receipt of ingress data. Furthermore, the compiled code causes control messages to be sent to circuitry associated with the interfaces, so as to control which buses associated with which processors, given interfaces are to connect to.

Abstract: An assembly and method for deploying, retrieving, and storing a cable having a minimum bend radius onto a drum. The assembly may comprise a frame, a rotatable drum carried by the frame, a levelwind carried by the frame, and a powertrain. The levelwind may comprise a rail spanning at least the width of the drum, and a traversable carriage carried by the rail. The levelwind may also comprise a cable guide carried by the carriage, where the cable guide comprises an elongated chute having contoured walls. The contoured walls of the chute include no bends having a radius less than the minimum bend radius of the cable. The powertrain may be operatively connected to rotate the drum about the drum axis and traverse the carriage along the rail. In some examples, the contoured walls of the chute are coated with a supplmentary coating.

Abstract: An assembly and method for deploying, retrieving, and storing a cable having a minimum bend radius onto a drum. The assembly may comprise a frame, a rotatable drum carried by the frame, a levelwind carried by the frame, and a powertrain. The levelwind may comprise a rail spanning at least the width of the drum, and a traversable carriage carried by the rail. The levelwind may also comprise a cable guide carried by the carriage, where the cable guide comprises an elongated chute having contoured walls. The contoured walls of the chute include no bends having a radius less than the minimum bend radius of the cable. The powertrain may be operatively connected to rotate the drum about the drum axis and traverse the carriage along the rail. In some examples, the contoured walls of the chute are coated with a supplmentary coating.

Abstract: A building component having first and second high density foam panels and improved bridging members for connecting the panels that extend between and may be molded into the panels. The bridging members include a pair of elongated end plates oriented in a top to bottom direction of the panels, a pair of substantially identical web members joining the end plates and being substantially symmetrically disposed above and below a central horizontal axis of the bridging member, and a pair of strip members oriented in the top to bottom direction of the panels intersecting the web members. The web members have a unique configuration that maximizes load bearing capacity with a minimum amount of material. The strip members may abut against and be substantially flush with respective inner surfaces of the foam panels to assist in positioning and forming the panels during molding. Seating areas for positioning horizontally and/or vertically disposed rebar in predetermined positions are also provided.

Abstract: The invention relates to a compound of formula (I) or a salt thereof: wherein: R1 is C1-4alkyl, C1-3fluoroalkyl, —CH2CH2OH or —CH2CH2CO2C1-2alkyl; R2 is a hydrogen atom (H), methyl or C1fluoroalkyl; R3 is optionally substituted C3-8cycloalkyl or optionally substituted mono-unsaturated-C5-7cycloalkenyl or an optionally substituted heterocyclic group of sub-formula (aa), (bb) or (cc); in which n1 and n2 independently are 1 or 2; and in which Y is O, S, SO2, or NR10; or R3 is a bicyclic group (dd) or (ee): and wherein X is NR4R5 or OR5a. The compounds are phosphodiesterase (PDE) inhibitors, in particular PDE4 inhibitors. Also provided is the use of a compound of formula (I), or a pharmaceutically acceptable salt thereof, in the manufacture of a medicament for the treatment and/or prophylaxis of an inflammatory and/or allergic disease in a mammal such as a human, for example chronic obstructive pulmonary disease (COPD), asthma, or allergic rhinitis.

Abstract: Combination of one or more CB2 modulators and one or more PDE4 inhibitors, and method of treating conditions which are mediated by the activity of CB2 receptors or conditions which are mediated by PDE4.

Abstract: A building component having first and second high density foam panels and improved bridging members for connecting the panels that extend between and may be molded into the panels. The bridging members include a pair of elongated end plates oriented in a top to bottom direction of the panels, a pair of substantially identical web members joining the end plates and being substantially symmetrically disposed above and below a central horizontal axis of the bridging member, and a pair of strip members oriented in the top to bottom direction of the panels intersecting the web members. The web members have a unique configuration that maximizes load bearing capacity with a minimum amount of material. The strip members may abut against and be substantially flush with respective inner surfaces of the foam panels to assist in positioning and forming the panels during molding. Seating areas for positioning horizontally and/or vertically disposed rebar in predetermined positions are also provided.

Abstract: A building component having first and second high density foam panels and improved bridging members for connecting the panels that extend between and may be molded into the panels. The bridging members include a pair of elongated end plates oriented in a top to bottom direction of the panels, a pair of substantially identical web members joining the end plates and being substantially symmetrically disposed above and below a central horizontal axis of the bridging member, and a pair of strip members oriented in the top to bottom direction of the panels intersecting the web members. The web members have a unique configuration that maximizes load bearing capacity with a minimum amount of material. The strip members may abut against and be substantially flush with respective inner surfaces of the foam panels to assist in positioning and forming the panels during molding. Seating areas for positioning horizontally and/or vertically disposed rebar in predetermined positions are also provided.

Abstract: A building component having first and second high density foam panels and improved bridging members for connecting the panels that extend between and may be molded into the panels. The bridging members include a pair of elongated end plates oriented in a top to bottom direction of the panels, a pair of substantially identical web members joining the end plates and being substantially symmetrically disposed above and below a central horizontal axis of the bridging member, and a pair of strip members oriented in the top to bottom direction of the panels intersecting the web members. The web members have a unique configuration that maximizes load bearing capacity with a minimum amount of material. The strip members may abut against and be substantially flush with respective inner surfaces of the foam panels to assist in positioning and forming the panels during molding. Seating areas for positioning horizontally and/or vertically disposed rebar in predetermined positions are also provided.

Abstract: A building component having first and second high density foam panels and improved bridging members for connecting the panels that extend between and may be molded into the panels. The bridging members include a pair of elongated end plates oriented in a top to bottom direction of the panels, a pair of substantially identical web members joining the end plates and being substantially symmetrically disposed above and below a central horizontal axis of the bridging member, and a pair of strip members oriented in the top to bottom direction of the panels intersecting the web members. The web members have a unique configuration that maximizes load bearing capacity with a minimum amount of material. The strip members may abut against and be substantially flush with respective inner surfaces of the foam panels to assist in positioning and forming the panels during molding. Seating areas for positioning horizontally and/or vertically disposed rebar in predetermined positions are also provided.

Abstract: This invention relates to treating pulmonary diseases such as obstructive pulmonary disease or asthma by administering a phosphodiesterase 4 inhibitor in combination with an anticholinergic agent.

Abstract: This invention relates to treating pulmonary diseases such as chronic obstructive pulmonary disease or asthma by administering a phosphodiesterase 4 inhibitor in combination with an H1-receptor antagonist.

Abstract: The present invention relates to novel amidino compound of formula (I): to a process for their manufacture, to pharmaceutical compositions containing them, and to their use in therapy, in particular their use as selective inhibitors of inducible nitric oxide synthase.

Abstract: A building component having first and second high density foam panels and improved bridging members for connecting the panels that extend between and may be molded into the panels. The bridging members include a pair of elongated end plates oriented in a top to bottom direction of the panels, a pair of substantially identical web members joining the end plates and being substantially symmetrically disposed above and below a central horizontal axis of the bridging member, and a pair of strip members oriented in the top to bottom direction of the panels intersecting the web members. The web members have a unique configuration that maximizes load bearing capacity with a minimum amount of material. The strip members may abut against and be substantially flush with respective inner surfaces of the foam panels to assist in positioning and forming the panels during molding. Seating areas for positioning horizontally and/or vertically disposed rebar in predetermined positions are also provided.

Abstract: The present invention relates to novel amidino compound of formula (I). to a process for their manufacture, to pharmaceutical compositions containing them, and to their use in therapy, in particular their use as selective inhibitors of inducible nitric oxide synthase.

Abstract: The present invention relates to novel amidino compound of formula (I).

Abstract: A compound of formula (I) ##STR1## wherein R.sup.1 is a C.sub.1-6 straight or branched chain alkyl group, a C.sub.2-6 alkenyl group, a C.sub.2-6 alkynyl group, a C.sub.3-6 cycloalkyl group or a C.sub.3-6 cycloalkylC.sub.1-6 alkyl group, each optionally substituted by one to three groups independently selected from: --CN; --NO.sub.2 ; a group --COR.sup.2 wherein R.sup.2 is hydrogen, C.sub.1-6 alkyl, --OR.sup.3 wherein R.sup.3 is hydrogen or C.sub.1-6 alkyl or NR.sup.4 R.sup.5 wherein R.sup.4 and R.sup.5 are independently selected from hydrogen or C.sub.1-6 alkyl; a group --S(O).sub.m R.sup.6 wherein m is 0, 1 or 2, R.sup.6 is hydrogen, C.sub.1-6 alkyl, hydroxy or NR.sup.7 R.sup.8 wherein R.sup.7 and R.sup.8 are independently hydrogen or C.sub.1-6 alkyl; a group PO(OR.sup.9).sub.2 wherein R.sup.9 is hydrogen or C.sub.1-6 alkyl; a group NR.sup.10 R.sup.11 wherein R.sup.10 and R.sup.11 are independently selected from hydrogen, C.sub.1-6 alkyl, --COR.sup.12 wherein R.sup.12 is hydrogen or C.sub.

Abstract: A compound of formula (I) wherein R1 is a C1-6 straight or branched chain alkyl group, a C2-6alkenyl group, a C2-6 alkynyl group, a C3-6cycloalkyl group or a C3-6cycloalkylC1-6alkyl group, each optionally substituted by one to three groups independently selected from: —CN; —NO2; a group —COR2 wherein R2 is hydrogen, C1-6 alkyl, —OR3 wherein R3 is hydrogen or C1-6alkyl or NR4R5 wherein R4 and R5 are independently selected from hydrogen or C1-6 alkyl; a group —S(O)mR6 wherein m is 0, 1 or 2, R6 is hydrogen, C1-6 alkyl, hydroxy or NR7R8 wherein R7 and R8 are independently hydrogen or C1-6 alkyl; a group PO(OR9)2 wherein R9 is hydrogen or C1-6 alkyl; a group NR10R11 wherein R10 and R11 are independently selected from hydrogen, C1-6 alkyl, —COR12 wherein R12 is hydrogen or C1-6 alkyl, or —S(O)m?R13 wherein m? is 0, 1 or 2 and R13 is hydrogen or C1-6 alkyl; halo; or a group —OR14 wherein R14 is hydrogen, C1-6 alkyl optionally substituted by one to three halo atoms, C6-10 aryl or —COR15 wherein R15 is hydroge