Patents by Inventor Graham Arthur William Rook

Graham Arthur William Rook has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Monoclonal antibodies and their production and use
    Patent number: 6391634
    Abstract: Monoclonal antibodies raised against cell walls of Group A Streptococci are specific to biological materials, e.g. immunoglobulins, having terminal N-acetylglucosamine residues and can be used in their detection, e.g. in the diagnosis of diseases characterized by their presence, e.g. rheumatoid arthritis and Crohn's disease.
    Type: Grant
    Filed: March 10, 1993
    Date of Patent: May 21, 2002
    Assignee: G. D. Searle & Co.
    Inventors: Graham Arthur William Rook, Jennifer Jane Edge
  • Method for delaying the onset of AIDS
    Patent number: 6210684
    Abstract: Antigenic and/or immunoregulatory material derived from Mycobacterium vaccae is useful for delaying the onset of AIDS with or without associated tuberculosis.
    Type: Grant
    Filed: May 16, 1995
    Date of Patent: April 3, 2001
    Assignee: Stranford Rock Limited
    Inventors: John Lawson Stanford, Graham Arthur William Rook
  • Immunotherapeutic agent and its use
    Patent number: 6056964
    Abstract: A method for delaying or preventing the growth or spread of a malignant neoplasm by administering to a subject in need material which comprises killed cells of Mycobacterium vaccae in an amount sufficient at least to delay or prevent the growth or spread of the neoplasm.
    Type: Grant
    Filed: October 25, 1996
    Date of Patent: May 2, 2000
    Assignee: Stanford Rook Limited
    Inventors: Graham Arthur William Rook, John Lawson Stanford
  • Use of estrone derivatives as steroid sulphatase inhibitors
    Patent number: 6013642
    Abstract: This invention relates to the use of stroid sulphate sulphatase inhibitors which prevent the normal physiological effect of DHEA or related steroids on inflammatory responses.
    Type: Grant
    Filed: April 14, 1997
    Date of Patent: January 11, 2000
    Inventors: Roland Foulkes, John Spencer Emtage, Mark William Bodmer, Martin Rae Wales, Graham Arthur William Rook
  • Mycobacterium vaccae for treatment of long term autoimmune conditions
    Patent number: 5885588
    Abstract: Antigenic and/or immunoregulatry material derived from Mycobacterium vaccae is useful in the treatment of mental diseases associated with an autoimmune reaction initiated by an infection and/or the auto immunologically mediated consequences (other than uveitis) of chronic infection.
    Type: Grant
    Filed: February 14, 1995
    Date of Patent: March 23, 1999
    Assignee: University College London
    Inventors: John Lawson Stanford, Graham Arthur William Rook
  • Treatment of psoriasis using dead cells of Mycobacterium vaccae
    Patent number: 5833996
    Abstract: Immunoregulatory material derived from Mycobacterium vaccae, especially dead cells of M. vaccae, are useful for the treatment of pathological conditions (other than mycobacterial disease and arthritic disease) in a patient in which the patient's IgG shows an abnormally high proportion of agalactosyl IgG and for the treatment of chronic inflammatory disorders (other than an arthritic disease) caused or accompanied by an abnormally high release from macrophages of interleukin-6 and/or tumor necrosis factor.
    Type: Grant
    Filed: May 16, 1995
    Date of Patent: November 10, 1998
    Assignee: University College London
    Inventors: John Lawson Stanford, Graham Arthur William Rook