Abstract: There is provided a method for distinguishing between sepsis and systemic inflammatory response syndrome (SIRS) in a patient, comprising: (i) determining the amount of one or more biomarker for sepsis, and one or more biomarker for SIRS in a sample obtained from a patient, wherein the one or more biomarker for sepsis is selected from the group consisting of: ITGB3, ITGA2B, MYL9, LCN2, TREML1, LCN15, CMTM5, PPBP, and PF4; and the one or more biomarker for SIRS is selected from the group consisting of: PLA2G7, ARHGEF10L, MYCL, TGFBI, and GPR124, (ii) comparing the amount of the one or more biomarker for sepsis determined in said sample in (i) to a corresponding reference value representative of a healthy individual, (iii) comparing the amount of the one or more biomarker for SIRS determined in said sample in (i) to a corresponding reference value representative of a healthy individual; wherein the patient is diagnosed as having sepsis, when an increase is observed in the one or more biomarker for sepsis, and no

Abstract: The present invention relates to a transcription factor gene that plays a key role in Solanaceae fruit ripening. Plants overexpressing the gene have fruits with deeper pigmentation and ripen more rapidly than controls. The invention also relates to transgenic plants comprising said gene, and methods of making said plants.

Abstract: A liquid cryogenic vaporizer and method of use are disclosed. The vaporizer includes a main tube, a cryogenic fluid inlet positioned proximate a first end of the main tube for receiving cryogenic fluid, and a second tube having a diameter smaller than the main tube, the second tube being in fluid communication with the main tube at a second end of the main tube opposite the cryogenic fluid inlet. The vaporizer further includes an outlet extending from the inner tube for expelling vaporized fluid. The second tube can be positioned within the main tube, and one or more velocity limiters are optionally included within the main tube along a fluid path.

Abstract: There is provided a method for distinguishing between sepsis and systemic inflammatory response syndrome (SIRS) in a patient, comprising: (i) determining the amount of one or more biomarker for sepsis, and one or more biomarker for SIRS in a sample obtained from a patient, wherein the one or more biomarker for sepsis is selected from the group consisting of: ITGB3, ITGA2B, MYL9, LCN2, TREML1, LCN15, CMTMS, PPBP, and PF4; and the one or more biomarker for SIRS is selected from the group consisting of: PLA2G7, ARHGEF10L, MYCL, TGFBI, and GPR124, (ii) comparing the amount of the one or more biomarker for sepsis determined in said sample in (i) to a corresponding reference value representative of a healthy individual, (iii) comparing the amount of the one or more biomarker for SIRS determined in said sample in (i) to a corresponding reference value representative of a healthy individual; wherein the patient is diagnosed as having sepsis, when an increase is observed in the one or more biomarker for sepsis, and no

Abstract: A liquid cryogenic vaporizer and method of use are disclosed. The vaporizer includes a main tube, a cryogenic fluid inlet positioned proximate a first end of the main tube for receiving cryogenic fluid, and a second tube having a diameter smaller than the main tube, the second tube being in fluid communication with the main tube at a second end of the main tube opposite the cryogenic fluid inlet. The vaporizer further includes an outlet extending from the inner tube for expelling vaporized fluid. The second tube can be positioned within the main tube, and one or more velocity limiters are optionally included within the main tube along a fluid path.

Abstract: Systems and Methods for Collaborative Vehicle Mission Operations are provided.

Abstract: Systems and Methods for Collaborative Vehicle Mission Operations are provided.

Abstract: Systems and Methods for Collaborative Vehicle Mission Operations are provided.

Abstract: Systems and methods for automated wiring and configuration verification are disclosed. A plurality of data buses may be tested utilizing a verification method disclosed herein. The verification method may include: transmitting a unique data sequence on each particular data bus of the plurality of data buses from a transmitting unit to a receiving unit, wherein the transmitting unit and the receiving unit are connected at least in part utilizing the particular data bus; analyzing a data sequence received at the receiving unit to determine a connection correctness for the particular data bus; and reporting the connection correctness for each particular data bus of the plurality of data buses to a user. The verification method is capable of not only detecting the presence of each bus, but also verifying the integrity of the connection provided by each bus. Various types of wiring faults may be detected effectively and efficiently.

Abstract: Embodiments are generally directed to a feedthrough for an implantable medical device. The feedthrough comprises an insulator having one or more conductors extending therethrough that is hermetically connected (joined) to a housing of the implantable medical device. More specifically, the housing includes an aperture and the insulator is configured be positioned in the aperture. Braze material is configured to be positioned in one or more indentations in at least one of the housing or the insulator such that the braze material is disposed in the indentations between the insulator and the housing.

Abstract: The present invention relates to novel biomarkers for determining the Alzheimer's disease status of a subject, and to uses of novel panels of biomarkers. AD is currently clinically diagnosed using tests of cognitive function. Studies have shown that the accuracy of the clinical diagnosis is between 65 and 90% using cognitive techniques. The present invention provides a method of determining the Alzheimer' s disease status of a subject comprising providing a sample of material obtained from the subject and determining the expression level of one or more genes selected from the group consisting of: TUBB, NEAT1, CENPB, AA482221 and CPSF3 in the sample.

Abstract: Embodiments are generally directed to a feedthrough for an implantable medical device. The feedthrough comprises an insulator having one or more conductors extending therethrough that is hermetically connected (joined) to a housing of the implantable medical device. More specifically, the housing includes an aperture and the insulator is configured be positioned in the aperture. Braze material is configured to be positioned in one or more indentations in at least one of the housing or the insulator such that the braze material is disposed in the indentations between the insulator and the housing.

Abstract: The present invention relates to the analysis of data to identify relationships between the input data and one or more conditions. One method of analyzing such data is by the use of neural networks which are non-linear statistical data modelling tools, the structure of which may be changed based on information that is passed through the network during a training phase. A known problem that affects neural networks is the issue of overtraining which arises in overcomplex or overspecified systems when the capacity of the network significantly exceeds the needed parameters. The present invention provides a method of analyzing data using a neural network with a constrained architecture that mitigates the problems associated with the prior art.

Abstract: The present invention relates to a transcription factor gene that plays a key role in Solanaceae fruit ripening. Plants overexpressing the gene have fruits with deeper pigmentation and ripen more rapidly than controls. The invention also relates to transgenic plants comprising said gene, and methods of making said plants.

Abstract: A time to event data analysis method and system. The present invention relates to the analysis of data to identify relationships between the input data and one or more conditions. One method of analysing such data is by the use of neural networks which are non-linear statistical data modelling tools, the structure of which may be changed based on information that is passed through the network during a training phase. A known problem that affects neural networks is the issue of overtraining which arises in overcomplex or overspecified systems when the capacity of the network significantly exceeds the needed parameters. The present invention provides a method of analysing data, such as bioinformatics or pathology data, using a neural network with a constrained architecture and providing a continuous output that can be used in various contexts and systems including prediction of time to an event, such as a specified clinical event.

Abstract: The present invention relates to the analysis of data to identify relationships between the input data and one or more conditions. One method of analysing such data is by the use of neural networks which are non-linear statistical data modelling tools, the structure of which may be changed based on information that is passed through the network during a training phase. A known problem that affects neural networks is the issue of overtraining which arises in overcomplex or overspecified systems when the capacity of the network significantly exceeds the needed parameters. The present invention provides a method of analysing data using a neural network with a constrained architecture that mitigates the problems associated with the prior art.

Abstract: The present invention relates to a polypeptide in which: (i) the N-terminal sequence includes the polypeptide sequence of the GBSSI (Granule Bound Starch Synthase I) or a derivative or fragment thereof, wherein said polypeptide sequence can bind to starch; and (ii) the C-terminal sequence includes a polypeptide sequence coding for at least one epitope of an antigen from a parasite of the Plasmodium type; the invention also relates to a polynucleotide coding for such polypeptide, a vector containing said polynucleotide, a cell transformed by such vector, a transformed organism including such transformed cell, a pharmaceutical composition containing such polypeptide, and the use of such polypeptide in the preparation of a drug for the prophylactic treatment of a subject suffering from a pathology associated with a Plasmodium-type parasite, preferably malaria.

Abstract: A connector for a plain end pipe comprising a housing (7) for location over the pipe, an annular recess (4) formed in an inner surface of the housing (7), a seal (1) located in the recess (4), a nipple (8) for the supply of grease under pressure, and segmental grippers of L-shaped cross section comprising a leg (6) and a foot (5) having a serrated inner surface for engagement with the pipe. Such connectors have wide tolerance within a certain range of nominal pipe outside diameter.

Abstract: An inflatable mattress for supporting patients comprises two inflatable longitudinal tubes extending along the respective longitudinal edges of the mattress and a plurality of inflatable transverse tubes. Each transverse tube has adjacent its end an aperture, with the longitudinal tube extending through the aligned apertures at one side of the mattress and the longitudinal tube extending through the aligned apertures at the other side of the mattress. The transverse tubes are selectively inflatable in various modes under microprocessor control.

Abstract: A pipe connector for attachment to a plain end pipe includes a housing (2) for location over the pipe end, an annular recess (4) formed in the inner surface of the housing, an inlet (10) for feeding a fluid under pressure into the recess, a sealing ring (6) in the recess, having at least three arcuate gripper elements (14) bonded thereto, the gripper elements having aligned recesses at the radially inward surfaces in which an O-ring seal (16) is mounted. After a pipe end is placed within the housing, fluid is pumped into the annular space (8) between the housing and seal ring (6), which pushes the seal ring and attached gripper elements radially inwardly to engage the pipe, the O-ring seal (16) forming a tight seal against the pipe. The plurality of gripper elements can conform to a pipe which is not perfectly round.