Abstract: The invention relates to a micro-nozzle array comprising a plurality of capillaries comprising a first silica-based material and a second silica-based material substantially surrounding the first silica-based material of the plurality of capillaries, and a plurality of nozzles extending beyond a face of the micro-nozzle array, each nozzle corresponding to a single capillary, wherein each nozzle comprises the first silica-based material. The micro-nozzle array may be used in hydrodynamic or electro-osmotic applications. In one embodiment the micro-nozzle array is a multiple electrospray emitter. The invention also relates to methods for preparing and using micro-nozzle arrays.

Abstract: The invention relates to a micro-nozzle array comprising a plurality of capillaries comprising a first silica-based material and a second silica-based material substantially surrounding the first silica-based material of the plurality of capillaries, and a plurality of nozzles extending beyond a face of the micro-nozzle array, each nozzle corresponding to a single capillary, wherein each nozzle comprises the first silica-based material. The micro-nozzle array may be used in hydrodynamic or electro-osmotic applications. In one embodiment the micro-nozzle array is a multiple electrospray emitter. The invention also relates to methods for preparing and using micro-nozzle arrays.

Abstract: Provided is a multi-channel electrospray emitter. The emitter includes a plurality of separate or distinct capillaries, each capillary being one channel and terminating in a nozzle, from which the analyte is sprayed. The nozzles may be raised above a face of the electrospray emitter. The multi-channel electrospray emitter may comprise a microstructured fiber. In one embodiment, the microstructured fiber may be a photonic crystal fiber.

Abstract: Provided is a frit having a body comprising a matrix material, and a plurality of microcapillaries formed within the matrix material, the microcapillaries substantially aligned with a longitudinal axis of the body. The frit may comprise a microstructured fibre, such as a photonic crystal fibre. The fit may be coupled to a fluidic conduit such as a chromatography column and/or a nanoelectrospray emitter. The frit may be used in applications such as solid phase extraction, electrospray ionization mass spectrometry, microreactor systems, and filtering particles in any fluid system where there is a need to retain particles.

Abstract: Provided is a multi-channel electrospray emitter. The emitter includes a plurality of separate or distinct capillaries, each capillary being one channel and terminating in a nozzle, from which the analyte is sprayed. The nozzles may be raised above a face of the electrospray emitter. The multi-channel electrospray emitter may comprise a microstructured fibre. In one embodiment, the microstructured fibre may be a photonic crystal fibre.

Abstract: A vapor atmosphere spray dryer can include a closed-loop circuit having a dryer, a bag house filter system, a fan, and a heater system which are fluidly connected together for circulating a mass of superheated vapor therethrough. A centrifugal atomizer is disposed within the dryer. A feed system delivers a supply of feed slurry to the centrifugal atomizer which discharges a supply of atomized feed slurry in the dryer for combination with the circulated mass of superheated vapor within the dryer. The closed loop circuit is constructed such that the circulated mass of superheated vapor has an operating pressure of at least 1 psi which is generated by the evaporation of the fluid in the atomized feed slurry in the dryer resulting from the combination of the supply of atomized feed slurry and the circulated mass of superheated vapor.