Patents by Inventor Graham Herbert Coombs

Graham Herbert Coombs has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Leishmania vaccine
    Patent number: 6890542
    Abstract: The present invention relates to the use of a live mutant Leishmania in the preparation of a vaccine and to vaccine formulations for use in immunizing mammals, such as dogs and/or humans. The mutant Leishmania comprises at least one defective cysteine proteinase gene.
    Type: Grant
    Filed: April 24, 2003
    Date of Patent: May 10, 2005
    Assignee: University Court of the University of Glasgow
    Inventors: Jeremy Charles Mottram, Graham Herbert Coombs
  • Leishmania vaccine
    Publication number: 20040005326
    Abstract: The present invention relates to the use of a live mutant Leishmania in the preparation of a vaccine and to vaccine formulations for use in immunising mammals, such as dogs and/or humans. The mutant Leishmania comprises at least one defective cysteine proteinase gene.
    Type: Application
    Filed: April 24, 2003
    Publication date: January 8, 2004
    Inventors: Jeremy Charles Mottram, Graham Herbert Coombs
  • Homocysteine desulphurase from the protozoan trichomonas vaginalis
    Patent number: 6306618
    Abstract: The present invention relates to an assay for determining homocysteine, cysteine, O-acetyl-L-serine and/or methionine levels in a biological sample using an enzyme that catalyzes the degradation of homocysteine, cysteine, O-acetyl-L-serine and methionine. The enzyme being more particularly homocysteine desulphurase, a polynucleotide fragment encoding protozoan homocysteine desulphurase, a recombinant vector comprising a polynucleotide fragment, transformed cells, the protozoan homocysteine desulphurase polypeptide, and pharmaceutical compositions comprising recombinant homocysteine desulphurase for use in medicine or veterinary medicine.
    Type: Grant
    Filed: March 29, 1999
    Date of Patent: October 23, 2001
    Assignee: University of the University of Glasgow
    Inventors: Graham Herbert Coombs, Jeremy Charles Mottram, David John Pritchard, Robert Stewart Campbell